Chapter 41 Antiemetic and Antinausea Drugs
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. The nurse has just completed the intravenous administration of a drug to a patient for the
prevention of chemotherapy-induced nausea and vomiting. What antiemetic drug has the patient
received?
a. granisetron
b. lorazepam
c. dexamethasone
d. prochlorperazine
ANS A
Granisetron hydrochloride (Kytril®), palonosetron (Aloxi®), and ondansetron (Zofran®) are beneficial in
preventing nausea and vomiting caused by chemotherapy. Lorazepam is an anxiolytic, and
dexamethasone is a corticosteroid. Prochlorperazine is an antidopaminergic medication.
DIF Cognitive Level Comprehension
2. Which primary anticholinergic medication is used as an antiemetic?
a. Meclizine hydrochloride
b. Prochlorperazine
c. Scopolamine hydrobromide
d. Metoclopramide hydrochloride
ANS C
Scopolamine hydrobromide injection is the primary anticholinergic drug used as an antiemetic. It has
potent effects on the vestibular nuclei, which are within the area of the brain that controls balance.
DIF Cognitive Level Comprehension
, 3. A patient receiving chemotherapy is prescribed ondansetron (Zofran) for treatment of nausea.
Which is an adverse effect of this antiemetic drug?
a. Dizziness
b. Headache
c. Dry mouth
d. Blurred vision
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. The nurse has just completed the intravenous administration of a drug to a patient for the
prevention of chemotherapy-induced nausea and vomiting. What antiemetic drug has the patient
received?
a. granisetron
b. lorazepam
c. dexamethasone
d. prochlorperazine
ANS A
Granisetron hydrochloride (Kytril®), palonosetron (Aloxi®), and ondansetron (Zofran®) are beneficial in
preventing nausea and vomiting caused by chemotherapy. Lorazepam is an anxiolytic, and
dexamethasone is a corticosteroid. Prochlorperazine is an antidopaminergic medication.
DIF Cognitive Level Comprehension
2. Which primary anticholinergic medication is used as an antiemetic?
a. Meclizine hydrochloride
b. Prochlorperazine
c. Scopolamine hydrobromide
d. Metoclopramide hydrochloride
ANS C
Scopolamine hydrobromide injection is the primary anticholinergic drug used as an antiemetic. It has
potent effects on the vestibular nuclei, which are within the area of the brain that controls balance.
DIF Cognitive Level Comprehension
, 3. A patient receiving chemotherapy is prescribed ondansetron (Zofran) for treatment of nausea.
Which is an adverse effect of this antiemetic drug?
a. Dizziness
b. Headache
c. Dry mouth
d. Blurred vision
