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Chapter 05 Gene Therapy and Pharmacogenomics

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Chapter 05 Gene Therapy and Pharmacogenomics

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Chapter 05: Gene Therapy and Pharmacogenomics



MULTIPLE CHOICE




1. Which is the most important compound that transfers genes from parents to offspring?

a. Chromatin

b. Deoxyribonucleic acid (DNA)

c. Alleles

d. Ribonucleic acid



ANS: B

It is now recognized that DNA is the most important body compound that serves to transfer genes

from parents to offspring.




DIF: Cognitive Level: Knowledge




2. Which is manufactured as a result of indirect gene therapy?

a. Vitamin K

b. epoetin (Eprex) c. Human insulin d. Heparin



ANS: C

A recombinant form of human insulin is one of the most widespread uses of indirect gene

therapy. DIF: Cognitive Level: Comprehension

3. Eugenics is defined as

a. the use of gene therapy to prevent disease.

, b. the development of new drugs based on gene therapy.

c. the intentional selection, before birth, of genotypes that are considered more desirable

than others.

d. the determination of genetic factors that influence a person’s response

to medications.

ANS: C

Eugenics is the intentional selection, before birth, of genotypes that are considered more desirable

than others. Eugenics is a major ethical issue related to gene therapy.

DIF: Cognitive Level: Knowledge




4. What is the main purpose of the Human Genome Project?

a. To study genetic diseases

b. To study genetic traits in humans

c. To discover new genetic diseases

d. To describe the entire genome of a human being




ANS: D

The Human Genome Project was undertaken to describe in detail the entire genome of a human being.

DIF: Cognitive Level: Knowledge

5. Genotyping for the presence of cytochrome P-450 2D6 (CYP2D6) enzymes and alleles will be helpful

in which area of medicine?

a. Cardiology

b. Psychiatry

c. Respirology

d. Oncology

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