Page 1 of 822
t5 t5 t5
TEST BANK t5
Katzung's Basic and Clinical Pharmacol
t5 t5 t5 t5t5
ogy, 16th Edition
t5 t5 t 5
by Todd W. Vanderah, Chapters 1 - 66
t5 t5 t5 t5 t5 t5 t5 t 5
Katzung's Basic and Clinical Pharmacology
t5 t5 t5 t5
, Page 2 of 822 t5 t5 t5
Table of Contents t5 t5
1. Introduction: The Nature of Drugs & Drug Development & Regulation
t5 t5 t5 t5 t5 t5 t5 t5 t5
2. Drug Receptors & Pharmacodynamics
t5 t5 t5
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
4. Drug Biotransformation
t5
5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology
t5 t5 t5
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs t5 t5 t5
8. Cholinoceptor-Blocking Drugs t5
9. Adrenoceptor Agonists & Sympathomimetic Drugs
t5 t5 t5 t5
10. Adrenoceptor Antagonist Drugs t5 t5
11. Antihypertensive Agents t5
12. Vasodilators & the Treatment of Angina Pectoris
t5 t5 t5 t5 t5 t5
13. Drugs Used in Heart Failure
t5 t5 t5 t5
14. Agents Used in Cardiac Arrhythmias
t5 t5 t5 t5
15. Diuretic Agents t5
16. Histamine, Serotonin, & the Ergot Alkaloids
t5 t5 t5 t5 t5
17. Vasoactive Peptides t5
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
t5 t5 t5 t5 t5 t5 t5
19. Nitric Oxide
t5
20. Drugs Used in Asthma
t5 t5 t5
21. Introduction to the Pharmacology of CNS Drugs
t5 t5 t5 t5 t5 t5
22. Sedative-Hypnotic Drugs t5
23. The Alcohols
t5
24. Antiseizure Drugs t5
25. General Anesthetics t5
26. Local Anesthetics
t5
27. Skeletal Muscle Relaxants
t5 t5
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
t5 t5 t5 t5 t5 t5 t5
29. Antipsychotic Agents & Lithium t5 t5 t5
30. Antidepressant Agents t5
31. Opioid Agonists & Antagonists
t5 t5 t5
32. Drugs of Abuse
t5 t5
33. Agents Used in Cytopenias; Hematopoietic Growth Factors
t5 t5 t5 t5 t5 t5
34. Drugs Used in Disorders of Coagulation
t5 t5 t5 t5 t5
35. Agents Used in Dyslipidemia
t5 t5 t5
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-
t5 t5 t5
Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
t5 t5 t5 t5 t5 t5 t5 t5 t5
37. Hypothalamic & Pituitary Hormones t5 t5 t5
Katzung's Basic and Clinical Pharmacology t5 t5 t5 t5
, Page 3 of 822 t5 t5 t5
38. Thyroid & Antithyroid Drugs
t5 t5 t5
39. Adrenocorticosteroids & Adrenocortical Antagonists t5 t5 t5
40. The Gonadal Hormones & Inhibitors
t5 t5 t5 t5
41. Pancreatic Hormones & Antidiabetic Drugs
t5 t5 t5 t5
42. Agents That Affect Bone Mineral Homeostasis
t5 t5 t5 t5 t5
43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
t5 t5 t5 t5 t5 t5 t5
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones
t5 t5 t5 t5 t5 t5
45. Aminoglycosides & Spectinomycin t5 t5
46. Sulfonamides, Trimethoprim, & Quinolones t5 t5 t5
47. Antimycobacterial Drugs t5
48. Antifungal Agents t5
49. Antiviral Agents t5
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
t5 t5 t5 t5 t5 t5
51. Clinical Use of Antimicrobial Agents
t5 t5 t5 t5
52. Antiprotozoal Drugs t5
53. Clinical Pharmacology of the Antihelminthic Drugs
t5 t5 t5 t5 t5
54. Cancer Chemotherapy
t5
55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
t5 t5 t5 t5 t5
57. Heavy Metal Intoxication & Chelators
t5 t5 t5 t5
58. Management of the Poisoned Patient t5 t5 t5 t5
59. Special Aspects of Perinatal & Pediatric Pharmacology
t5 t5 t5 t5 t5 t5
60. Special Aspects of Geriatric Pharmacology
t5 t5 t5 t5
61. Dermatologic Pharmacology t5
62. Drugs Used in the Treatment of Gastrointestinal Diseases
t5 t5 t5 t5 t5 t5 t5
63. Therapeutic & Toxic Potential of Over-the-Counter Agents
t5 t5 t5 t5 t5 t5
64. Dietary Supplements & Herbal Medications
t5 t5 t5 t5
65. Rational Prescribing & Prescription Writing
t5 t5 t5 t5
66. Important Drug Interactions & Their Mechanisms
t5 t5 t5 t5 t5
Katzung's Basic and Clinical Pharmacology t5 t5 t5 t5
, Page 4 of 822 t5 t5 t5
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
1.
A nurse working in radiology administers iodine to a patient who is havin
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
g a computed tomography (CT) scan. The nurse working on the oncology un
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
it administers chemotherapy to patients who have cancer. At the Public Healt
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
h Department, a nurse administers a measles-mumps-
t5 t5 t5 t5 t5 t5
rubella (MMR) vaccine to a 14-month- t5 t5 t5 t5 t5
old child as a routine immunization. Which branch of pharmacology best des
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
cribes the actions of all three nurses?
t5 t5 t5 t5 t5 t 5
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are in
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
volved with clinical pharmacology or pharmacotherapeutics, which is a bran
t5 t5 t5 t5 t5 t5 t5 t5 t5
ch of pharmacology that deals with the uses of drugs to treat, prevent, and di
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
agnose disease. The radiology nurse is administering a drug to help diagnose
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
a disease. The oncology nurse is administering a drug to help treat a disease.
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
Pharmacoeconomics includes any costs involved in drug therapy. t5 t5 t5 t5 t5 t5 t5
Pharmacodynamics involves how a drug affects the body and pharmacokineti t5 t5 t5 t5 t5 t5 t5 t5 t5
cs is how the body acts on the body.
t5 t5 t5 t5 t5 t5 t5 t5
2.
A physician has ordered intramuscular (IM) injections of morphine, a nar
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
cotic, every 4 hours as needed for pain in a motor vehicle accident victim. Th
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
e nurse is aware this drug has a high abuse potential. Under what category w
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
ould morphine be classified?
t5 t5 t5
A) Schedule I t5
B) Schedule II t5
Katzung's Basic and Clinical Pharmacology t5 t5 t5 t5
t5 t5 t5
TEST BANK t5
Katzung's Basic and Clinical Pharmacol
t5 t5 t5 t5t5
ogy, 16th Edition
t5 t5 t 5
by Todd W. Vanderah, Chapters 1 - 66
t5 t5 t5 t5 t5 t5 t5 t 5
Katzung's Basic and Clinical Pharmacology
t5 t5 t5 t5
, Page 2 of 822 t5 t5 t5
Table of Contents t5 t5
1. Introduction: The Nature of Drugs & Drug Development & Regulation
t5 t5 t5 t5 t5 t5 t5 t5 t5
2. Drug Receptors & Pharmacodynamics
t5 t5 t5
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
4. Drug Biotransformation
t5
5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology
t5 t5 t5
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs t5 t5 t5
8. Cholinoceptor-Blocking Drugs t5
9. Adrenoceptor Agonists & Sympathomimetic Drugs
t5 t5 t5 t5
10. Adrenoceptor Antagonist Drugs t5 t5
11. Antihypertensive Agents t5
12. Vasodilators & the Treatment of Angina Pectoris
t5 t5 t5 t5 t5 t5
13. Drugs Used in Heart Failure
t5 t5 t5 t5
14. Agents Used in Cardiac Arrhythmias
t5 t5 t5 t5
15. Diuretic Agents t5
16. Histamine, Serotonin, & the Ergot Alkaloids
t5 t5 t5 t5 t5
17. Vasoactive Peptides t5
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
t5 t5 t5 t5 t5 t5 t5
19. Nitric Oxide
t5
20. Drugs Used in Asthma
t5 t5 t5
21. Introduction to the Pharmacology of CNS Drugs
t5 t5 t5 t5 t5 t5
22. Sedative-Hypnotic Drugs t5
23. The Alcohols
t5
24. Antiseizure Drugs t5
25. General Anesthetics t5
26. Local Anesthetics
t5
27. Skeletal Muscle Relaxants
t5 t5
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
t5 t5 t5 t5 t5 t5 t5
29. Antipsychotic Agents & Lithium t5 t5 t5
30. Antidepressant Agents t5
31. Opioid Agonists & Antagonists
t5 t5 t5
32. Drugs of Abuse
t5 t5
33. Agents Used in Cytopenias; Hematopoietic Growth Factors
t5 t5 t5 t5 t5 t5
34. Drugs Used in Disorders of Coagulation
t5 t5 t5 t5 t5
35. Agents Used in Dyslipidemia
t5 t5 t5
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-
t5 t5 t5
Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
t5 t5 t5 t5 t5 t5 t5 t5 t5
37. Hypothalamic & Pituitary Hormones t5 t5 t5
Katzung's Basic and Clinical Pharmacology t5 t5 t5 t5
, Page 3 of 822 t5 t5 t5
38. Thyroid & Antithyroid Drugs
t5 t5 t5
39. Adrenocorticosteroids & Adrenocortical Antagonists t5 t5 t5
40. The Gonadal Hormones & Inhibitors
t5 t5 t5 t5
41. Pancreatic Hormones & Antidiabetic Drugs
t5 t5 t5 t5
42. Agents That Affect Bone Mineral Homeostasis
t5 t5 t5 t5 t5
43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
t5 t5 t5 t5 t5 t5 t5
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones
t5 t5 t5 t5 t5 t5
45. Aminoglycosides & Spectinomycin t5 t5
46. Sulfonamides, Trimethoprim, & Quinolones t5 t5 t5
47. Antimycobacterial Drugs t5
48. Antifungal Agents t5
49. Antiviral Agents t5
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
t5 t5 t5 t5 t5 t5
51. Clinical Use of Antimicrobial Agents
t5 t5 t5 t5
52. Antiprotozoal Drugs t5
53. Clinical Pharmacology of the Antihelminthic Drugs
t5 t5 t5 t5 t5
54. Cancer Chemotherapy
t5
55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
t5 t5 t5 t5 t5
57. Heavy Metal Intoxication & Chelators
t5 t5 t5 t5
58. Management of the Poisoned Patient t5 t5 t5 t5
59. Special Aspects of Perinatal & Pediatric Pharmacology
t5 t5 t5 t5 t5 t5
60. Special Aspects of Geriatric Pharmacology
t5 t5 t5 t5
61. Dermatologic Pharmacology t5
62. Drugs Used in the Treatment of Gastrointestinal Diseases
t5 t5 t5 t5 t5 t5 t5
63. Therapeutic & Toxic Potential of Over-the-Counter Agents
t5 t5 t5 t5 t5 t5
64. Dietary Supplements & Herbal Medications
t5 t5 t5 t5
65. Rational Prescribing & Prescription Writing
t5 t5 t5 t5
66. Important Drug Interactions & Their Mechanisms
t5 t5 t5 t5 t5
Katzung's Basic and Clinical Pharmacology t5 t5 t5 t5
, Page 4 of 822 t5 t5 t5
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
1.
A nurse working in radiology administers iodine to a patient who is havin
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
g a computed tomography (CT) scan. The nurse working on the oncology un
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
it administers chemotherapy to patients who have cancer. At the Public Healt
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
h Department, a nurse administers a measles-mumps-
t5 t5 t5 t5 t5 t5
rubella (MMR) vaccine to a 14-month- t5 t5 t5 t5 t5
old child as a routine immunization. Which branch of pharmacology best des
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
cribes the actions of all three nurses?
t5 t5 t5 t5 t5 t 5
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are in
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
volved with clinical pharmacology or pharmacotherapeutics, which is a bran
t5 t5 t5 t5 t5 t5 t5 t5 t5
ch of pharmacology that deals with the uses of drugs to treat, prevent, and di
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
agnose disease. The radiology nurse is administering a drug to help diagnose
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
a disease. The oncology nurse is administering a drug to help treat a disease.
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
Pharmacoeconomics includes any costs involved in drug therapy. t5 t5 t5 t5 t5 t5 t5
Pharmacodynamics involves how a drug affects the body and pharmacokineti t5 t5 t5 t5 t5 t5 t5 t5 t5
cs is how the body acts on the body.
t5 t5 t5 t5 t5 t5 t5 t5
2.
A physician has ordered intramuscular (IM) injections of morphine, a nar
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
cotic, every 4 hours as needed for pain in a motor vehicle accident victim. Th
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
e nurse is aware this drug has a high abuse potential. Under what category w
t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5 t5
ould morphine be classified?
t5 t5 t5
A) Schedule I t5
B) Schedule II t5
Katzung's Basic and Clinical Pharmacology t5 t5 t5 t5