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NURS 676 ADVANCED PHARMACOLOGY FINAL EXAM REVIEW QUESTIONS AND CORRECT ANSWERS latest update GRADED A+

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NURS 676 ADVANCED PHARMACOLOGY FINAL EXAM REVIEW QUESTIONS AND CORRECT ANSWERS latest update GRADED A+.

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NURS 676 ADVANCED PHARMACOLOGY |//\\|| |//\\|| |//\\| |//\\|




FINAL EXAM REVIEW QUESTIONS AND ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




CORRECT ANSWERS latest update GRADED A+. ||//\\|| |//\\| |//\\|| |//\\|| |//\\|




Why are nitrate-free periods every 24 hours necessary for the patient on
|//\\|| ||//\\|| ||//\\|| ||//\\|| |//\\| |//\\|| |//\\|| |//\\| ||//\\|| |//\\|| ||//\\|| ||//\\||




nitroglycerin therapy? - ANSWER : To inhibit the development of tolerance ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




What does a low level of thyroid-stimulating hormone indicate? - ANSWER :
||//\\|| ||//\\|| ||//\\|| |//\\| ||//\\|| ||//\\|| |/\\|| |//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




Hyperthroidism


What would be the best option to treat a newly diagnosed patient with a low TSH
||//\\|| ||//\\|| |/\\|| |//\\| ||//\\|| ||//\\|| |/\\|| |//\\|| |//\\|| |/\\|| ||//\\|| |//\\|| |//\\|| ||//\\|| ||//\\|| ||//\\||




level with? - ANSWER : Propanolol (Inderal)
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Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANSWER |/\\|| |/\\|| |//\\|| |//\\|| |//\\|| |//\\| ||//\\|| |//\\|| ||//\\|| ||//\\||




: Aldosterone antagonist
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Heparin exerts its therapeutic action by what? - ANSWER : Upregulating the
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |//\\|| |/\\||




activity of one of the body's natural anticoagulant molecules, antithrombin III
|//\\|| ||//\\|| |//\\| ||//\\|| |/\\|| ||//\\|| |//\\|| ||//\\|| ||//\\|| ||//\\||




What physiologic action happens when the offending drug is administered during
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |/\\||




an anaphylactic reaction. - ANSWER : Mast cells liberate large doses of
|//\\|| |//\\|| ||//\\|| ||//\\|| |//\\|| |//\\|| |//\\| |/\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




histamine.

,What are two systemic psoriasis medications? - ANSWER : Photo- therapy and
||//\\|| |//\\|| ||//\\|| ||//\\|| |/\\|| ||//\\|| |//\\|| |//\\|| | //\\|| ||//\\|| ||//\\|| ||//\\||




topical corticosteroids ||//\\||




What is the first choice of drug therapy for the majority of patients with
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |//\\| |//\\| |/\\|| ||//\\|| |//\\|| |/\\|| ||//\\|| ||//\\|| ||//\\||




uncomplicated stage I hypertension? - ANSWER : Thiazide diuretics ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




What is the effect of cardiac glycosides? - ANSWER : Digitalis glycosides have
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |//\\||




a negative chronotropic effect on the cardiac muscle cells.
|//\\|| |//\\|| |//\\| ||//\\|| ||//\\|| |//\\|| ||//\\|| |//\\| ||//\\||




Amenorrhea is the most common side effect of which birth control medication? - ||//\\|| |//\\| |/\\|| |//\\|| |//\\|| |/\\|| ||//\\|| |//\\|| |//\\|| |//\\|| ||//\\|| ||//\\|| ||//\\||




ANSWER : Medroxyprogesterone (Depo-Provera) ||//\\|| ||//\\|| ||//\\||




What is an anti-hypertensive agent which competes with epinephrine for available
||//\\|| |//\\|| |/\\|| |//\\| ||//\\|| |//\\| |//\\|| ||//\\|| |//\\| ||//\\|| ||//\\||




beta-receptor sites? - ANSWER : Atenolol (Tenormin) ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




What type of action does nitrates have on the body? - ANSWER :
||//\\|| |//\\| |//\\| |/\\|| |//\\|| |/\\|| |/\\|| ||//\\|| |/\\|| ||//\\ || |//\\|| |//\\||




Reduction in systemic venous tone. |//\\| |/\\|| |//\\| |//\\|




What is the recommended level of low-density lipoprotein cholesterol (LDL)
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |//\\|| ||//\\|| ||//\\|| |//\\||




for patients with known coronary artery disease? - ANSWER : 100mg/dl or
||//\\|| ||//\\|| |/\\|| ||//\\|| |/\\|| |//\\| ||//\\|| |//\\|| |//\\|| ||//\\|| ||//\\|| ||//\\||




less.

,What is the MOA of group IV anti-dysrhythmia drugs? - ANSWER : Depressing
||//\\|| ||//\\|| ||//\\|| |//\\| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




phase 4 depolarization and lengthening phases 1 and 2 repolarization.
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




Which drug therapy should be used to lower the serum concentration of thyroid
||//\\|| ||//\\|| |/\\|| |//\\|| |/\\|| |//\\|| |/\\|| |//\\|| |/\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




hormones and re-establish eumetabolic state in a patient with Graves' disease? - ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




ANSWER : Anti-thyroid drugs. ||//\\|| ||//\\|| ||//\\||




Which type of diuretic would be used for a stage I hypertension in a patient with
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |/\\|| |//\\|| ||//\\|| ||//\\|| |//\\|| |//\\| ||//\\|| |//\\|| ||//\\|| ||//\\|| ||//\\||




renal insufficiency? - ANSWER : Loop diuretic.
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




What drug should be considered as first-line therapy for a client with hypertension
||//\\|| ||//\\|| ||//\\|| |/\\|| ||//\\|| |/\\|| |//\\|| |//\\| |//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




and heart failure? - ANSWER : Enalapril (Vasotec)
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




Which drug is considered safe for hypertension treatment during pregnancy? -
|//\\|| |//\\| |//\\| ||//\\|| |//\\| |/\\|| ||//\\|| |//\\| ||//\\|| ||//\\|| ||//\\||




ANSWER : Methyldopa (Aldomet) ||//\\|| ||//\\|| ||//\\||




What drug will reduce afterload because it is an alpha-adrenergic blocker? -
||//\\|| ||//\\|| ||//\\|| |//\\| ||//\\|| |//\\| |//\\|| ||//\\|| |//\\|| ||//\\|| ||//\\|| ||//\\||




ANSWER : Prazosin (Minipress) ||//\\|| ||//\\|| ||//\\||




What is an expected effect of the use of a beta-adrenergic blocker to control
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |//\\| |//\\| ||//\\|| ||//\\|| |//\\|| ||//\\|| ||//\\|| |//\\|




angina? - ANSWER : Reduced force of cardiac contraction.
|//\\|| |//\\|| |//\\| |//\\|| ||//\\|| |/\\|| |/\\|| |//\\|




What side effect should be monitored closely in the elderly when taking Metformin
||//\\|| |//\\| ||//\\|| |//\\| |/\\|| |/\\|| |/\\|| ||//\\|| |//\\| |//\\|| ||//\\|| ||//\\|| ||//\\||




(Glucophage) for type 2 diabetes? - ANSWER : Lactic acidosis. ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||

, What is the primary role of cytochrome p-450 in the liver? - ANSWER :
||//\\|| ||//\\|| |/\\|| |//\\| |//\\| ||//\\|| |//\\| |//\\|| |//\\|| |//\\| |//\\|| |//\\|| |//\\||




Deactivate and detoxify medications and other substances. |//\\| |/\\|| |/\\|| |/\\|| |//\\| ||//\\||




What is a component of Vitamin K-dependent clotting factors? - ANSWER :
||//\\|| ||//\\|| |//\\|| |//\\| ||//\\|| ||//\\|| |//\\| |//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




Prothrombin


How are IV morphine and nitroglycerin beneficial in acute heart failure?
|//\\|| ||//\\|| |/\\|| |/\\|| |//\\| |/\\|| |//\\| |/\\|| |/\\|| ||//\\||




- ANSWER : Decrease preload.
|//\\|| |//\\| |//\\|| |//\\|




What is the purpose of administering a vasodilating drug to a patient in heart
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |/\\|| ||//\\|| |//\\| |//\\| ||//\\|| |//\\|| |//\\|| ||//\\|| ||//\\||




failure? - ANSWER : Decrease afterload. ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




What are some contrindications for HMG-co A reductase inhibitors (statins)?
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




- ANSWER : They cause myopathies, especially at higher doses or in
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| |//\\|| |//\\||




combination with certain drugs. They should never be used in patients taking ||//\\|| ||//\\|| ||//\\|| ||//\\|| |/\\|| ||//\\|| ||//\\|| |//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




Warfarin (Coumadin). ||//\\||




Which drug can reduce serum LDL the most in patients with hyperlipidemia? -
||//\\|| ||//\\|| ||//\\|| |/\\|| ||//\\|| |//\\| |/\\|| ||//\\|| |//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




ANSWER : Lovastatin (Mevacor) ||//\\|| ||//\\|| ||//\\||




Which drug is contrindicated in a patient with Myasthena Gravis? - ANSWER :
||//\\|| |//\\|| |//\\| |//\\|| |/\\|| |//\\| ||//\\|| |//\\|| |/\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||




Procainamide (Pronestyl). ||//\\||




What action is most effective in decreasing the risk of hyperkalemia associated with
||//\\|| |/\\|| ||//\\|| ||//\\|| |/\\|| ||//\\|| |//\\|| |/\\|| ||//\\|| |//\\|| ||//\\|| |/\\|| |//\\|




the start of angiotensin-converting enzyme inhibitor
|//\\|| |//\\|| |//\\| |/\\|| |/\\||

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