Genetic Analysis: An Integrated Approach
Mark Sanders, & John Bowman
3rd Edition
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,Table of Contents
Chapter 01 The Molecular Basis of Heredity, Variation, and Evolution 1
Chapter 02 Transmission Genetics 21
Chapter 03 Cell Division and Chromosome Heredity 41
Chapter 04 Gene Interaction 59
Chapter 05 Genetic Linkage and Mapping in Eukaryotes 81
Chapter 06 Genetic Analysis and Mapping in Bacteria and Bacteriophages 102
Chapter 07 DNA Structure and Replication 122
Chapter 08 Molecular Biology and Transcription and RNA Processing 138
Chapter 09 The Molecular Biology of Translation 156
Chapter 10 Eukaryotic Chromosome Abnormalities and Molecular Organization 172
Chapter 11 Gene Mutation, DNA Repair, and Homologous Recombination 190
Chapter 12 Regulation of Gene Expression in Bacteria and Bacteriophages 203
Chapter 13 Regulation of Gene Expression in Eukaryotes 227
Chapter 14 Forward Genetics and Recombinant DNA Technology 241
Chapter 15 Recombinant DNA Technology and Its Applications 254
Chapter 16 Genomics-Genetics from a Whole-Genome Perspective 270
Chapter 17 Cytoplasmic Inheritance and the Evolution of Organelle Genomes 284
Chapter 18 Developmental Genetics 298
Chapter 19 Genetic Analysis of Quantitative Traits 313
Chapter 20 Population Genetics and Evolution at the Population, Species, and Molecular
Levels 328
Application A Human Hereditary Disease and Genetic Counseling 346
Application B Human Genetic Screening 352
Application C The Genetics of Cancer 358
Application D Human Evolutionary Genetics 364
Application E Forensic Genetics 370
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Test Bank - Genetic Analysis: An Integrated Approach, 3rd Edition (Sanders, 2019)
Genetic Analysis: An Integrated Approach, 3e (Sanders)
Chapter 1 The Molecular Basis of Heredity, Variation, and Evolution
1.1 Multiple-Choice Questions
1) Sexual reproduction uses ________ to generate ________ gametes, which join at fertilization.
A) meiosis; haploid
B) mitosis; haploid
C) meiosis; diploid
D) mitosis; diploid
E) mitosis; identical
Answer: A
Section: 1.1
Skill: Remembering/Understanding
2) When a diploid cell divides by mitosis, the result is ________.
A) identical haploid cells
B) identical diploid cells
C) unique diploid cells
D) unique haploid cells
E) a zygote
Answer: B
Section: 1.1
Skill: Remembering/Understanding
3) Modern genetics consists of three major branches. Which of these branches, also known as
"transmission genetics," involves the study of the transmission of traits and characteristics in
successive generations?
A) evolutionary
B) Mendelian
C) molecular
D) population
E) reproductive
Answer: B
Section: 1.1
Skill: Remembering/Understanding
4) You identify a new unicellular organism with multiple chromosomes organized by proteins
within the cell's nucleus. Into which of the three domains of life might this organism fit?
A) Archaea
B) Bacteria
C) Eukarya
D) Archaea or Bacteria
E) Archaea or Eukarya
Answer: C
Section: 1.1
Skill: Applying/Analyzing
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Test Bank - Genetic Analysis: An Integrated Approach, 3rd Edition (Sanders, 2019)
5) Watson and Crick used evidence from several studies to determine the structure of DNA.
What conclusion were they able to draw from Rosalind Franklin's X-ray diffraction data,
specifically?
A) DNA consists of four types of nucleotide bases: A, T, C, and G.
B) DNA nucleotides form complementary base pairs.
C) Adenine pairs with thymine and cytosine pairs with guanine when they are on opposite DNA
strands.
D) DNA is a duplex, with two strands forming a double helix.
E) The DNA strands are antiparallel, and the strands are held together by hydrogen bonds.
Answer: D
Section: 1.2
Skill: Remembering/Understanding
LO: S1.2
6) What kind of bond is formed between the 5′ phosphate group of one nucleotide and the 3′
hydroxyl (OH) group of the adjacent nucleotide?
A) ionic bond
B) phosphodiester bond
C) hydrogen bond
D) disulfide bond
E) hydroxyl bond
Answer: B
Section: 1.2
Skill: Remembering/Understanding
LO: S1.2
7) What kind of bond is formed between complementary base pairs to join the two DNA strands
into a double helix?
A) ionic bond
B) phosphodiester bond
C) hydrogen bond
D) disulfide bond
E) peptide bond
Answer: C
Section: 1.2
Skill: Remembering/Understanding
LO: S1.2
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