NSG 535 Exam 1 (Coagulation) LATEST
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UPDATE
hemostasis - CORRECT ANSWERS ✔✔process that stops bleeding
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that follows vessel injury, and stops clotting when it isn't needed
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1. constrict vessel in area of damage
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2. form platelet plug (temporary)
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3. seal it with fibrin
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platelets - CORRECT ANSWERS ✔✔have receptors on them to
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bind Von Willebrand
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primary hemostasis - CORRECT ANSWERS ✔✔forming a platelet
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plug
platelets - CORRECT ANSWERS ✔✔non-nucleated
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1/3 ____ volume stored in spleen
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lifespan 8-12 days |\ |\
platelet count - CORRECT ANSWERS ✔✔general indicator of bone
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marrow health |\
,collagen - CORRECT ANSWERS ✔✔endothelial damage exposes
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_____ and other subendothelial substances that call out to
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platelets to show up in that area
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platelet plug - CORRECT ANSWERS ✔✔platelets adhere to sub
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endothelium (von willebrand aids in this process) |\ |\ |\ |\ |\ |\
once adherence occurs, platelets are activated by many
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substances and change shape to form ________ |\ |\ |\ |\ |\ |\
unstable - CORRECT ANSWERS ✔✔platelet plug is _______
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but its formation activates the clotting cascade to make a more
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stable clot |\
secondary hemostasis - CORRECT ANSWERS ✔✔making fibrin
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coagulation cascade makes fibrin to seal platelet plug
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coagulation cascade - CORRECT ANSWERS ✔✔________ (intrinsic
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and extrinsic) works to do 1 thing:
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fibrinogen -> fibrin |\ |\
make fibrin to stabilize clot
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, coagulation cascade - CORRECT ANSWERS ✔✔generates fibrin to
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stabilize the platelet plug
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intrinsic pathway - CORRECT ANSWERS ✔✔components all
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present in blood in inactive forms
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coagulation cascade |\
extrinsic pathway - CORRECT ANSWERS ✔✔activated by tissue
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damage (tissue factor) |\ |\
coagulation cascade |\
common pathway - CORRECT ANSWERS ✔✔final pathway that
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results in stable fibrin plug
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coagulation cascade |\
calcium - CORRECT ANSWERS ✔✔necessary co-factor in the
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intrinsic and extrinsic pathway
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factor X - CORRECT ANSWERS ✔✔common pathway starts with:
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Vitamin K dependent factors - CORRECT ANSWERS ✔✔Factor 2, 7,
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9, 10
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UPDATE
hemostasis - CORRECT ANSWERS ✔✔process that stops bleeding
|\ |\ |\ |\ |\ |\ |\ |\
that follows vessel injury, and stops clotting when it isn't needed
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
1. constrict vessel in area of damage
|\ |\ |\ |\ |\ |\
2. form platelet plug (temporary)
|\ |\ |\ |\
3. seal it with fibrin
|\ |\ |\ |\
platelets - CORRECT ANSWERS ✔✔have receptors on them to
|\ |\ |\ |\ |\ |\ |\ |\ |\
bind Von Willebrand
|\ |\
primary hemostasis - CORRECT ANSWERS ✔✔forming a platelet
|\ |\ |\ |\ |\ |\ |\ |\
plug
platelets - CORRECT ANSWERS ✔✔non-nucleated
|\ |\ |\ |\
1/3 ____ volume stored in spleen
|\ |\ |\ |\ |\
lifespan 8-12 days |\ |\
platelet count - CORRECT ANSWERS ✔✔general indicator of bone
|\ |\ |\ |\ |\ |\ |\ |\ |\
marrow health |\
,collagen - CORRECT ANSWERS ✔✔endothelial damage exposes
|\ |\ |\ |\ |\ |\ |\
_____ and other subendothelial substances that call out to
|\ |\ |\ |\ |\ |\ |\ |\ |\
platelets to show up in that area
|\ |\ |\ |\ |\ |\
platelet plug - CORRECT ANSWERS ✔✔platelets adhere to sub
|\ |\ |\ |\ |\ |\ |\ |\ |\
endothelium (von willebrand aids in this process) |\ |\ |\ |\ |\ |\
once adherence occurs, platelets are activated by many
|\ |\ |\ |\ |\ |\ |\ |\
substances and change shape to form ________ |\ |\ |\ |\ |\ |\
unstable - CORRECT ANSWERS ✔✔platelet plug is _______
|\ |\ |\ |\ |\ |\ |\
but its formation activates the clotting cascade to make a more
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
stable clot |\
secondary hemostasis - CORRECT ANSWERS ✔✔making fibrin
|\ |\ |\ |\ |\ |\
coagulation cascade makes fibrin to seal platelet plug
|\ |\ |\ |\ |\ |\ |\
coagulation cascade - CORRECT ANSWERS ✔✔________ (intrinsic
|\ |\ |\ |\ |\ |\ |\
and extrinsic) works to do 1 thing:
|\ |\ |\ |\ |\ |\
fibrinogen -> fibrin |\ |\
make fibrin to stabilize clot
|\ |\ |\ |\
, coagulation cascade - CORRECT ANSWERS ✔✔generates fibrin to
|\ |\ |\ |\ |\ |\ |\ |\
stabilize the platelet plug
|\ |\ |\
intrinsic pathway - CORRECT ANSWERS ✔✔components all
|\ |\ |\ |\ |\ |\ |\
present in blood in inactive forms
|\ |\ |\ |\ |\
coagulation cascade |\
extrinsic pathway - CORRECT ANSWERS ✔✔activated by tissue
|\ |\ |\ |\ |\ |\ |\ |\
damage (tissue factor) |\ |\
coagulation cascade |\
common pathway - CORRECT ANSWERS ✔✔final pathway that
|\ |\ |\ |\ |\ |\ |\ |\
results in stable fibrin plug
|\ |\ |\ |\
coagulation cascade |\
calcium - CORRECT ANSWERS ✔✔necessary co-factor in the
|\ |\ |\ |\ |\ |\ |\ |\
intrinsic and extrinsic pathway
|\ |\ |\
factor X - CORRECT ANSWERS ✔✔common pathway starts with:
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Vitamin K dependent factors - CORRECT ANSWERS ✔✔Factor 2, 7,
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9, 10
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