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NR 565 ADVANCED PHARMACOLOGY
MIDTERM EXAM 2025-
CHAMBERLAIN BRAND NEW ACTUAL
EXAM WITH ANSWERS.
Alendronate patient education - correct answer -minimize risk of
esophagitis by swallowing the pill whole with a full glass of water,
then sit up for at least 30 min but 60 min preferred. intake of food
prevents absorption, take this med 30 min prior to other intake
Which dietary supplement interferes with Ibandronate absorption?
- correct answer -calcium, magnesium, iron
1st line treatment of osteoporosis - correct answer -alendronate
Is allopurinol safe to use in a patient with renal dysfunction? -
correct answer -yes - drug of choice for patients with renal
dysfunction or who over produce uric acid
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Baseline diagnostics for DMARDS - correct answer -CBC with
WBC differential
s/s of infection (TB and hepatitis)
malignancies
rule out pregnancy
ALT, AST, serum creatinine
comprehensive history and physical exam
assess risk for immunocompetence and liver and renal status
Baseline data for Methotrexate (DMARD) - correct answer -chest
x-ray, emphasis on pulm and GI status
which DMARD needs ophthalmologic and cardiac exam? - correct
answer -hydroxychloroquine
black box warning for Raloxifene - correct answer -risk for venous
thromboembolic events (DVT, PE, stroke)
Behaviors that should predict controlled substance addiction -
correct answer -reinforcing properties of drugs - pleasurable
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(euphoria) or reduce unpleasant experience (reduce anxiety and
stress
physical dependence
physiological dependence (well-being depends on drug)
social factors (peer pressure)
drug availability (Drugs in hospitals - reason for nurses or
pharmacist abuse)
vulnerability of individual
impulsive
low tolerance for frustration
rebellious against social norms
depressive, anxiety, and anti-social personality disorders
abuse other drugs
Treatment of chronic pain with pregabalin - correct answer -
adjuvant analgesic for neuropathic pain
Effective in diabetic neuropathy, seizures, central neuropathy,
postherpetic neuralgia, and fibromyalgia
adverse effects of pregabalin - correct answer -Sedation/drowsy,
dizziness, and ataxia, blurred vision, difficulty thinking
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GI bleeding is linked to - correct answer -COX-2 inhibitors and
NSAID
patient education with colchicine - correct answer -only when
needed to relieve an attack: Start taking this medicine at the first
sign of the attack for best results. Stop taking this medicine as
soon as the pain is relieved or at the first sign of nausea,
vomiting, stomach pain, or diarrhea.
longer you wait to start with attack, less effective it might be
Which drugs are high risk in pregnancy with RA? - correct answer
-methotrexate
leflunomide
biologics: anti-TNF agents, rituximab and abatacept (end in -
mab)
Which drugs are safe for pregnancy with RA ? - correct answer -
NSAIDs, corticosteroids, plus several DMARDs, including
sulfasalazine and hydroxychloroquine
NR 565 ADVANCED PHARMACOLOGY
MIDTERM EXAM 2025-
CHAMBERLAIN BRAND NEW ACTUAL
EXAM WITH ANSWERS.
Alendronate patient education - correct answer -minimize risk of
esophagitis by swallowing the pill whole with a full glass of water,
then sit up for at least 30 min but 60 min preferred. intake of food
prevents absorption, take this med 30 min prior to other intake
Which dietary supplement interferes with Ibandronate absorption?
- correct answer -calcium, magnesium, iron
1st line treatment of osteoporosis - correct answer -alendronate
Is allopurinol safe to use in a patient with renal dysfunction? -
correct answer -yes - drug of choice for patients with renal
dysfunction or who over produce uric acid
, Page | 2
Baseline diagnostics for DMARDS - correct answer -CBC with
WBC differential
s/s of infection (TB and hepatitis)
malignancies
rule out pregnancy
ALT, AST, serum creatinine
comprehensive history and physical exam
assess risk for immunocompetence and liver and renal status
Baseline data for Methotrexate (DMARD) - correct answer -chest
x-ray, emphasis on pulm and GI status
which DMARD needs ophthalmologic and cardiac exam? - correct
answer -hydroxychloroquine
black box warning for Raloxifene - correct answer -risk for venous
thromboembolic events (DVT, PE, stroke)
Behaviors that should predict controlled substance addiction -
correct answer -reinforcing properties of drugs - pleasurable
, Page | 3
(euphoria) or reduce unpleasant experience (reduce anxiety and
stress
physical dependence
physiological dependence (well-being depends on drug)
social factors (peer pressure)
drug availability (Drugs in hospitals - reason for nurses or
pharmacist abuse)
vulnerability of individual
impulsive
low tolerance for frustration
rebellious against social norms
depressive, anxiety, and anti-social personality disorders
abuse other drugs
Treatment of chronic pain with pregabalin - correct answer -
adjuvant analgesic for neuropathic pain
Effective in diabetic neuropathy, seizures, central neuropathy,
postherpetic neuralgia, and fibromyalgia
adverse effects of pregabalin - correct answer -Sedation/drowsy,
dizziness, and ataxia, blurred vision, difficulty thinking
, Page | 4
GI bleeding is linked to - correct answer -COX-2 inhibitors and
NSAID
patient education with colchicine - correct answer -only when
needed to relieve an attack: Start taking this medicine at the first
sign of the attack for best results. Stop taking this medicine as
soon as the pain is relieved or at the first sign of nausea,
vomiting, stomach pain, or diarrhea.
longer you wait to start with attack, less effective it might be
Which drugs are high risk in pregnancy with RA? - correct answer
-methotrexate
leflunomide
biologics: anti-TNF agents, rituximab and abatacept (end in -
mab)
Which drugs are safe for pregnancy with RA ? - correct answer -
NSAIDs, corticosteroids, plus several DMARDs, including
sulfasalazine and hydroxychloroquine
