Certified Compounded Sterile Preparation
Technician (CSPT) Exam Guide 2025/2026 |
Practice & Final Exam Questions with 100%
Verified Correct Answers
CSPT Certification Exam | USP <797> & <800> Standards, Sterile Compounding Procedures,
Hazardous Drug Handling, Aseptic Technique, Quality Assurance, and Pharmacy Law |
Expert-Verified Q&A | Certification-Ready
Introduction
This document provides the complete Certified Compounded Sterile Preparation Technician
(CSPT) Exam Guide for the 2025/2026 certification cycle. It covers essential exam domains
including sterile compounding standards, aseptic technique, hazardous and non-hazardous drug
handling, quality assurance, infection control, and regulatory compliance. Each included answer
is confirmed for accuracy, ensuring confidence for both exam success and safe, effective practice
in sterile compounding pharmacy environments.
Answer Format
All correct answers are highlighted in bold and green, with clear rationales that reinforce
understanding of compounding safety, pharmacy law, and best practices in sterile medication
preparation.
CSPT Exam Guide Q&A | Verified 2025/2026 Content | Exam-Aligned | Prepared
for Certification & Professional Practice Excellence
1. What is the primary purpose of USP <797> standards?
a) To regulate hazardous drug handling
b) To ensure sterile compounding safety
c) To manage pharmacy inventory
d) To process insurance claims
b) To ensure sterile compounding safety
Rationale: USP <797> provides standards for sterile compounding to prevent contamination
and ensure patient safety.
2. What is the minimum frequency for cleaning a laminar airflow hood?
a) Daily
b) Weekly
c) Monthly
d) Annually
,a) Daily
Rationale: USP <797> requires daily cleaning of laminar airflow hoods to maintain a sterile
environment.
3. Which personal protective equipment (PPE) is required when handling
hazardous drugs per USP <800>?
a) Single gloves and gown
b) Double gloves, gown, and eye protection
c) Mask and shoe covers only
d) Gown and hair cover only
b) Double gloves, gown, and eye protection
Rationale: USP <800> mandates double gloves, a gown, and eye protection to minimize
exposure to hazardous drugs.
4. What is the beyond-use date (BUD) for a low-risk sterile compound
prepared in a cleanroom with no stability data?
a) 12 hours
b) 24 hours
c) 48 hours
d) 7 days
c) 48 hours
Rationale: USP <797> specifies a 48-hour BUD for low-risk sterile compounds at room
temperature without stability data.
5. What is the purpose of a biological safety cabinet (BSC) in sterile
compounding?
a) To store medications
b) To handle hazardous drugs safely
c) To measure drug quantities
d) To label prescriptions
b) To handle hazardous drugs safely
Rationale: BSCs provide a controlled environment for safe handling of hazardous drugs per USP
<800>.
6. What is the correct order of donning PPE for sterile compounding?
a) Gown, gloves, shoe covers, hair cover
b) Shoe covers, hair cover, gown, gloves
c) Gloves, gown, hair cover, shoe covers
d) Hair cover, gloves, shoe covers, gown
b) Shoe covers, hair cover, gown, gloves
Rationale: USP <797> specifies donning PPE in order of least to most contaminated areas: shoe
covers, hair cover, gown, then gloves.
7. What is the primary purpose of environmental monitoring in a sterile
compounding area?
a) To track medication inventory
, b) To ensure a contamination-free environment
c) To process insurance claims
d) To order controlled substances
b) To ensure a contamination-free environment
Rationale: Environmental monitoring (e.g., air sampling) ensures the cleanroom meets USP
<797> sterility standards.
8. Which solution is commonly used to clean a compounding area?
a) Tap water
b) 70% isopropyl alcohol
c) Bleach solution
d) Soap and water
b) 70% isopropyl alcohol
Rationale: USP <797> recommends 70% isopropyl alcohol for its antimicrobial properties in
cleaning compounding areas.
9. What is the minimum air change per hour (ACPH) requirement for an
ISO Class 7 cleanroom?
a) 10 ACPH
b) 20 ACPH
c) 30 ACPH
d) 40 ACPH
c) 30 ACPH
Rationale: USP <797> requires at least 30 air changes per hour for an ISO Class 7 cleanroom to
maintain air quality.
10. What is the purpose of a media fill test in sterile compounding?
a) To measure drug potency
b) To validate aseptic technique competency
c) To track medication expiration
d) To label compounded preparations
b) To validate aseptic technique competency
Rationale: Media fill tests simulate compounding to verify personnel maintain sterility during
preparation.
11. Which type of syringe is used for precise measurement in sterile
compounding?
a) Oral syringe
b) Luer-lock syringe
c) Insulin syringe
d) Tuberculin syringe
b) Luer-lock syringe
Rationale: Luer-lock syringes ensure secure connections and precise measurements for sterile
compounding.
Technician (CSPT) Exam Guide 2025/2026 |
Practice & Final Exam Questions with 100%
Verified Correct Answers
CSPT Certification Exam | USP <797> & <800> Standards, Sterile Compounding Procedures,
Hazardous Drug Handling, Aseptic Technique, Quality Assurance, and Pharmacy Law |
Expert-Verified Q&A | Certification-Ready
Introduction
This document provides the complete Certified Compounded Sterile Preparation Technician
(CSPT) Exam Guide for the 2025/2026 certification cycle. It covers essential exam domains
including sterile compounding standards, aseptic technique, hazardous and non-hazardous drug
handling, quality assurance, infection control, and regulatory compliance. Each included answer
is confirmed for accuracy, ensuring confidence for both exam success and safe, effective practice
in sterile compounding pharmacy environments.
Answer Format
All correct answers are highlighted in bold and green, with clear rationales that reinforce
understanding of compounding safety, pharmacy law, and best practices in sterile medication
preparation.
CSPT Exam Guide Q&A | Verified 2025/2026 Content | Exam-Aligned | Prepared
for Certification & Professional Practice Excellence
1. What is the primary purpose of USP <797> standards?
a) To regulate hazardous drug handling
b) To ensure sterile compounding safety
c) To manage pharmacy inventory
d) To process insurance claims
b) To ensure sterile compounding safety
Rationale: USP <797> provides standards for sterile compounding to prevent contamination
and ensure patient safety.
2. What is the minimum frequency for cleaning a laminar airflow hood?
a) Daily
b) Weekly
c) Monthly
d) Annually
,a) Daily
Rationale: USP <797> requires daily cleaning of laminar airflow hoods to maintain a sterile
environment.
3. Which personal protective equipment (PPE) is required when handling
hazardous drugs per USP <800>?
a) Single gloves and gown
b) Double gloves, gown, and eye protection
c) Mask and shoe covers only
d) Gown and hair cover only
b) Double gloves, gown, and eye protection
Rationale: USP <800> mandates double gloves, a gown, and eye protection to minimize
exposure to hazardous drugs.
4. What is the beyond-use date (BUD) for a low-risk sterile compound
prepared in a cleanroom with no stability data?
a) 12 hours
b) 24 hours
c) 48 hours
d) 7 days
c) 48 hours
Rationale: USP <797> specifies a 48-hour BUD for low-risk sterile compounds at room
temperature without stability data.
5. What is the purpose of a biological safety cabinet (BSC) in sterile
compounding?
a) To store medications
b) To handle hazardous drugs safely
c) To measure drug quantities
d) To label prescriptions
b) To handle hazardous drugs safely
Rationale: BSCs provide a controlled environment for safe handling of hazardous drugs per USP
<800>.
6. What is the correct order of donning PPE for sterile compounding?
a) Gown, gloves, shoe covers, hair cover
b) Shoe covers, hair cover, gown, gloves
c) Gloves, gown, hair cover, shoe covers
d) Hair cover, gloves, shoe covers, gown
b) Shoe covers, hair cover, gown, gloves
Rationale: USP <797> specifies donning PPE in order of least to most contaminated areas: shoe
covers, hair cover, gown, then gloves.
7. What is the primary purpose of environmental monitoring in a sterile
compounding area?
a) To track medication inventory
, b) To ensure a contamination-free environment
c) To process insurance claims
d) To order controlled substances
b) To ensure a contamination-free environment
Rationale: Environmental monitoring (e.g., air sampling) ensures the cleanroom meets USP
<797> sterility standards.
8. Which solution is commonly used to clean a compounding area?
a) Tap water
b) 70% isopropyl alcohol
c) Bleach solution
d) Soap and water
b) 70% isopropyl alcohol
Rationale: USP <797> recommends 70% isopropyl alcohol for its antimicrobial properties in
cleaning compounding areas.
9. What is the minimum air change per hour (ACPH) requirement for an
ISO Class 7 cleanroom?
a) 10 ACPH
b) 20 ACPH
c) 30 ACPH
d) 40 ACPH
c) 30 ACPH
Rationale: USP <797> requires at least 30 air changes per hour for an ISO Class 7 cleanroom to
maintain air quality.
10. What is the purpose of a media fill test in sterile compounding?
a) To measure drug potency
b) To validate aseptic technique competency
c) To track medication expiration
d) To label compounded preparations
b) To validate aseptic technique competency
Rationale: Media fill tests simulate compounding to verify personnel maintain sterility during
preparation.
11. Which type of syringe is used for precise measurement in sterile
compounding?
a) Oral syringe
b) Luer-lock syringe
c) Insulin syringe
d) Tuberculin syringe
b) Luer-lock syringe
Rationale: Luer-lock syringes ensure secure connections and precise measurements for sterile
compounding.
