8/22/25, 5:54 PM HESI PN Practice Questions
HESI PN practice study guide exam \complete
questions and accurate detailed answers latest
update 2025-2026
What are the final a) heart rate
parameters that produce b) stroke volume
blood pressure? (SATA) c) peripheral resistance
a) heart rate
b) stroke volume
c) peripheral resistance
d) neuroendocrine hormones
e) muscle tone
A client begins taking an b) mood
antidepressant drug
during the second day of
hospitalization. Which
assessment is most
important for the nurse to
include in this client's plan
of care while the client is
taking the
antidepressant?
a) appetite
b) mood
c) withdrawal
d) energy level
\ 1/140
,8/22/25, 5:54 PM HESI PN Practice Questions
Based on the documentation a) give the rubella vaccine subcutaneously
in the medical record,
which action should the
nurse implement next?
1. vital signs every 4 hours
2. hydrocodone bitartrate 5
milligrams
(mg)/acetaminophen 500
mg (Vicodin) 2 tablet every
6 hours as need for pain
3. hydrocodone bitartrate 5
mg/acetaminophen 600 mg
(Vicodin) 2 tablets every 6
hours as needed for pain
4. hemoglobin &
hematocrit (H&H) on
admission
5. administer rubella vaccine if
indicated
6) administer Rho(D)
immune globulin
(RhoGAM) if indicated
a) give the rubella vaccine
subcutaneously
b) observe the mother
breastfeeding her infant
c) call the surgery for the
infant's blood type result
d) administer Vicodin one
tablet for pain
A client is admitted to the a) encourage mobilization and ambulation
hospital with a diagnosis
of pneumonia. Which
intervention should the
nurse implement to prevent
complications associated
with pneumonia?
a) encourage mobilization and
\ 2/140
,8/22/25, 5:54 PM HESI PN Practice Questions
ambulation
b) encourage energy
conservation with
complete bed rest
c) provide humidified
oxygen per nasal
cannula
d) restrict PO and intravenous
fluids
The practical nurse is 1000/2.5 = 400
preparing to administer a
prescription for cefazolin
(Kefzol) 600 mg IM every
six hours. The available vial
is labeled, "Cefazolin
(Kefzol) 1gram," and the
instructions for
reconstitution state, "For IM
use add 2mL sterile water
for injection. Total volume
after reconstitution =
2.5mL." When reconstituted,
how many milligrams are in
each mil of solution?
The nurse is planning to 1. intravenous
evaluate the effectiveness 2. sublingual
of several drugs 3. intramuscular
4. subcutaneous
administered by different
5, oral
routes. Arrange the routes
of administration in the
order from fastest to
slowest rate of absorption.
- subcutaneous
- intravenous
- intramuscluar
- sublingual
- oral
\ 3/140
, 8/22/25, 5:54 PM HESI PN Practice Questions
Which nursing activity is c) observe a client rotate the subcutaneous site for an insulin
within the scope of practice pump
for the practical nurse>
a) complete an admission
assessment in the normal
newborn nursery
b) discontinue a central
venous catheter that has
become dislodge
c) observe a client rotate the
subcutaneous site for an
insulin pump
d) monitor a continuous
narcotic epidural for a
postoperative client
After morning dressing b) provide perianal care and collect clean linens for the dressing
changes are completed, a change
male client who has
paraplegia contaminates his
ischial decubiti dressing with
a diarrhea stool. What
activity is best for the
nurse to assign to the
unlicensed assistive
personnel?
a) identify the need for
additional supplies to
provide an extra dressing
change
b) provide perianal care
and collect clean linens
for the dressing change
c) document the diarrhea
that necessitates an
additional dressing
\ 4/140
HESI PN practice study guide exam \complete
questions and accurate detailed answers latest
update 2025-2026
What are the final a) heart rate
parameters that produce b) stroke volume
blood pressure? (SATA) c) peripheral resistance
a) heart rate
b) stroke volume
c) peripheral resistance
d) neuroendocrine hormones
e) muscle tone
A client begins taking an b) mood
antidepressant drug
during the second day of
hospitalization. Which
assessment is most
important for the nurse to
include in this client's plan
of care while the client is
taking the
antidepressant?
a) appetite
b) mood
c) withdrawal
d) energy level
\ 1/140
,8/22/25, 5:54 PM HESI PN Practice Questions
Based on the documentation a) give the rubella vaccine subcutaneously
in the medical record,
which action should the
nurse implement next?
1. vital signs every 4 hours
2. hydrocodone bitartrate 5
milligrams
(mg)/acetaminophen 500
mg (Vicodin) 2 tablet every
6 hours as need for pain
3. hydrocodone bitartrate 5
mg/acetaminophen 600 mg
(Vicodin) 2 tablets every 6
hours as needed for pain
4. hemoglobin &
hematocrit (H&H) on
admission
5. administer rubella vaccine if
indicated
6) administer Rho(D)
immune globulin
(RhoGAM) if indicated
a) give the rubella vaccine
subcutaneously
b) observe the mother
breastfeeding her infant
c) call the surgery for the
infant's blood type result
d) administer Vicodin one
tablet for pain
A client is admitted to the a) encourage mobilization and ambulation
hospital with a diagnosis
of pneumonia. Which
intervention should the
nurse implement to prevent
complications associated
with pneumonia?
a) encourage mobilization and
\ 2/140
,8/22/25, 5:54 PM HESI PN Practice Questions
ambulation
b) encourage energy
conservation with
complete bed rest
c) provide humidified
oxygen per nasal
cannula
d) restrict PO and intravenous
fluids
The practical nurse is 1000/2.5 = 400
preparing to administer a
prescription for cefazolin
(Kefzol) 600 mg IM every
six hours. The available vial
is labeled, "Cefazolin
(Kefzol) 1gram," and the
instructions for
reconstitution state, "For IM
use add 2mL sterile water
for injection. Total volume
after reconstitution =
2.5mL." When reconstituted,
how many milligrams are in
each mil of solution?
The nurse is planning to 1. intravenous
evaluate the effectiveness 2. sublingual
of several drugs 3. intramuscular
4. subcutaneous
administered by different
5, oral
routes. Arrange the routes
of administration in the
order from fastest to
slowest rate of absorption.
- subcutaneous
- intravenous
- intramuscluar
- sublingual
- oral
\ 3/140
, 8/22/25, 5:54 PM HESI PN Practice Questions
Which nursing activity is c) observe a client rotate the subcutaneous site for an insulin
within the scope of practice pump
for the practical nurse>
a) complete an admission
assessment in the normal
newborn nursery
b) discontinue a central
venous catheter that has
become dislodge
c) observe a client rotate the
subcutaneous site for an
insulin pump
d) monitor a continuous
narcotic epidural for a
postoperative client
After morning dressing b) provide perianal care and collect clean linens for the dressing
changes are completed, a change
male client who has
paraplegia contaminates his
ischial decubiti dressing with
a diarrhea stool. What
activity is best for the
nurse to assign to the
unlicensed assistive
personnel?
a) identify the need for
additional supplies to
provide an extra dressing
change
b) provide perianal care
and collect clean linens
for the dressing change
c) document the diarrhea
that necessitates an
additional dressing
\ 4/140
