WGU: D027:
ADVANCED
N
PATHOPHAR
U
R
MACOLOGICA
SI
N
L
G
FOUNDATIONS
WGU: D027: Advanced Pathopharmacological Foundations
,What is the difference between ulcerative colitis and
Crohn's disease in terms of symptoms and body impacts?
- ANSWER-- Crohn's is inflammation and scarring in the
intestine (bowel) disease lining of all of the digestive
tract and worsens after eating
- Ulcerative colitis is inflammation of the bowel/digestive
tract and is only in the innermost lining of the large
intestines (colon) and rectum
N
U
What is the difference between Fragile X-Associated
Tremor/Ataxia Syndrome (FXTAS) and Fragile X
R
Syndrome (FXS)? - ANSWER-- Both caused by mutations
SI
on the FMR1 gene, but they are caused by different
changes in this gene
N
- FXS is caused by a full mutation
G
- FXTAS is a premutation
- FXS is present at birth, but display these features in
early life
- FXTAS develops in adulthood (usually after age 50) and
the symptoms may appear slowly and develop over the
years
WGU: D027: Advanced Pathopharmacological Foundations
,- FXTAS individuals are usually healthy with normal
cognitive skills prior to the onset
How is Alzheimer's treated? - ANSWER-- There is no cure,
but there are pharmacological and non-pharmacological
treatments
- Cholinesterase inhibitors
N
- Memantine (namenda)
U
What are cholinesterase inhibitors prescribed for? -
R
ANSWER-- To treat symptoms related to memory,
SI
thinking, language, judgment, and other processes
- Helps delay or slow the worsening of symptoms
N
G
What does cholinesterase inhibitors do? - ANSWER--
Prevent the breakdown of acetylcholine, a chemical
messenger that is important for learning and memory
- Supports communication among nerve cells by keeping
the acetylcholine high
WGU: D027: Advanced Pathopharmacological Foundations
, What are some commonly prescribed cholinesterase
inhibitors? - ANSWER-- Donepezil (aricept)
- Galantamine (razadyne)
- Rivastigmine (exeleon)
Which cholinesterase inhibitor can be used for all stages
of Alzheimer's? - ANSWER-- Donepezil (aricept)
N
U
Which cholinesterase inhibitor can be used for mild-to-
moderate stages of Alzheimer's? - ANSWER--
R
Galantamine (razadyne)
SI
- Rivastigmine (exeleon)
N
What medication combination is used to treat moderate-
G
to-severe Alzheimer's? - ANSWER-- Memantine
(namenda) and donepezil (aricept)
What is memantine (namenda) used for? - ANSWER--
Prescribed to improve memory, attention, reason,
language, and the ability to perform simple tasks
WGU: D027: Advanced Pathopharmacological Foundations
ADVANCED
N
PATHOPHAR
U
R
MACOLOGICA
SI
N
L
G
FOUNDATIONS
WGU: D027: Advanced Pathopharmacological Foundations
,What is the difference between ulcerative colitis and
Crohn's disease in terms of symptoms and body impacts?
- ANSWER-- Crohn's is inflammation and scarring in the
intestine (bowel) disease lining of all of the digestive
tract and worsens after eating
- Ulcerative colitis is inflammation of the bowel/digestive
tract and is only in the innermost lining of the large
intestines (colon) and rectum
N
U
What is the difference between Fragile X-Associated
Tremor/Ataxia Syndrome (FXTAS) and Fragile X
R
Syndrome (FXS)? - ANSWER-- Both caused by mutations
SI
on the FMR1 gene, but they are caused by different
changes in this gene
N
- FXS is caused by a full mutation
G
- FXTAS is a premutation
- FXS is present at birth, but display these features in
early life
- FXTAS develops in adulthood (usually after age 50) and
the symptoms may appear slowly and develop over the
years
WGU: D027: Advanced Pathopharmacological Foundations
,- FXTAS individuals are usually healthy with normal
cognitive skills prior to the onset
How is Alzheimer's treated? - ANSWER-- There is no cure,
but there are pharmacological and non-pharmacological
treatments
- Cholinesterase inhibitors
N
- Memantine (namenda)
U
What are cholinesterase inhibitors prescribed for? -
R
ANSWER-- To treat symptoms related to memory,
SI
thinking, language, judgment, and other processes
- Helps delay or slow the worsening of symptoms
N
G
What does cholinesterase inhibitors do? - ANSWER--
Prevent the breakdown of acetylcholine, a chemical
messenger that is important for learning and memory
- Supports communication among nerve cells by keeping
the acetylcholine high
WGU: D027: Advanced Pathopharmacological Foundations
, What are some commonly prescribed cholinesterase
inhibitors? - ANSWER-- Donepezil (aricept)
- Galantamine (razadyne)
- Rivastigmine (exeleon)
Which cholinesterase inhibitor can be used for all stages
of Alzheimer's? - ANSWER-- Donepezil (aricept)
N
U
Which cholinesterase inhibitor can be used for mild-to-
moderate stages of Alzheimer's? - ANSWER--
R
Galantamine (razadyne)
SI
- Rivastigmine (exeleon)
N
What medication combination is used to treat moderate-
G
to-severe Alzheimer's? - ANSWER-- Memantine
(namenda) and donepezil (aricept)
What is memantine (namenda) used for? - ANSWER--
Prescribed to improve memory, attention, reason,
language, and the ability to perform simple tasks
WGU: D027: Advanced Pathopharmacological Foundations
