BIO 373 SPECIFICATION EXAM
QUESTIONS AND ANSWERS
Differentiation - Correct Answers -Generation of specialized cells during development
Last stage in generation of a new cell - Correct Answers -Differentiation: A cell first has
to commit to a certain fate
Specification - Correct Answers -First step in two part commitment process- Labile
stage, can be reversed, cell can differentiate autonomously in a neutral environment
Transcription Factors - Correct Answers -Morphogenic determinants- cell has all the
information to drive its fate, no need for any interaction
Blastomere Development - Correct Answers -Each blastomere will develop and form its
different cell type even after separation from the other blastomeres
Determination - Correct Answers -Second step in two part commitment process- cells
can differentiate autonomously regardless of the environment
Autonomous (strategy of specification) - Correct Answers -Blastomere (cell originating
from early cleavage of embryo) acquires a set of transcription factors from egg
cytoplasm
Conditional (strategy for specification) - Correct Answers -Fate is achieved through
interaction with other cells. Neighboring cells influence development (paracrine factors)
Syncytial (strategy for specification) - Correct Answers -Insects: Early development of
insects- nuclei divide, not cells --> one cytoplasm, several nuclei= syncytium
QUESTIONS AND ANSWERS
Differentiation - Correct Answers -Generation of specialized cells during development
Last stage in generation of a new cell - Correct Answers -Differentiation: A cell first has
to commit to a certain fate
Specification - Correct Answers -First step in two part commitment process- Labile
stage, can be reversed, cell can differentiate autonomously in a neutral environment
Transcription Factors - Correct Answers -Morphogenic determinants- cell has all the
information to drive its fate, no need for any interaction
Blastomere Development - Correct Answers -Each blastomere will develop and form its
different cell type even after separation from the other blastomeres
Determination - Correct Answers -Second step in two part commitment process- cells
can differentiate autonomously regardless of the environment
Autonomous (strategy of specification) - Correct Answers -Blastomere (cell originating
from early cleavage of embryo) acquires a set of transcription factors from egg
cytoplasm
Conditional (strategy for specification) - Correct Answers -Fate is achieved through
interaction with other cells. Neighboring cells influence development (paracrine factors)
Syncytial (strategy for specification) - Correct Answers -Insects: Early development of
insects- nuclei divide, not cells --> one cytoplasm, several nuclei= syncytium