Radiation Therapy || with Complete Solution.
roentgen correct answers who defined radiation oncology in 1928 - the key to modern radiation
oncology?
radiation oncology correct answers _____ ______: The utilization of ionizing radiation in the
treatment of disease
cell mitosis, oxygenated correct answers ionization is most effective during ___ _____ and in
well ______ conditions
DNA correct answers Then it appears oxygen fixes the lesion and the target molecule is _____
direct correct answers ______ effect: the target molecule is ionized and it is most likely DNA
considering sensitivity during mitosis
indirect correct answers ______ effect: another molecule is ionized and the energy is chemically
transferred to the target molecule (DNA). H2O is thought to be the primary source of unstable
chemical elements which result from combination with free O2
indirect correct answers Due to the prevalence of H2O and the importance of O2 in cell kill we
believe most damage results from _____ effect.
oxygen enhancement ratio correct answers ______ _____ _____: dose hypoxic / dose
oxygenated This ratio is 3 to 1 for the clinical range of x-radiation
reproductive death correct answers _______ _____: the major effect of radiation on dividing
cells. Cells fail to produce viable progeny
, interphase death correct answers ______ ______: seen in non-dividing cells such as mature
nervous system or muscle tissues. Cells simply lose the ability to function and die...typically at
high doses of radiation.
fractionation correct answers ______: A tumor tends to outgrow its blood supply. By dividing the
total dose into a number of relatively small daily doses (fractions) the tumor is allowed to
reoxygenate. This also allows normal cells to repair PLD (potentially lethal damage)
therapeutic ratio correct answers _____ _____: Typically this determines the curability of a
lesion and the decision to treat. Defined as the Normal Tissue Tolerance / Tumor Control Dose.
Practically, the tumor control dose depends on the tissue of origin and the size of the tumor
Seminoma
Hodgkins Disease
Neuroblastoma
Wilms Tumor
Larynx
Squamous Cell less than 4cm correct answers what are some different types of radiocurable
tumors?
3500-6000 rads correct answers what exposure dose is typically used for radiocurable tumors?
6000-7500 correct answers Size typically greater than 2cm but less than 4cm with cureative
doses of ____-______rads
Oral Cavity
Pharynx
Bladder
Cervix & Uterus
Ovary
roentgen correct answers who defined radiation oncology in 1928 - the key to modern radiation
oncology?
radiation oncology correct answers _____ ______: The utilization of ionizing radiation in the
treatment of disease
cell mitosis, oxygenated correct answers ionization is most effective during ___ _____ and in
well ______ conditions
DNA correct answers Then it appears oxygen fixes the lesion and the target molecule is _____
direct correct answers ______ effect: the target molecule is ionized and it is most likely DNA
considering sensitivity during mitosis
indirect correct answers ______ effect: another molecule is ionized and the energy is chemically
transferred to the target molecule (DNA). H2O is thought to be the primary source of unstable
chemical elements which result from combination with free O2
indirect correct answers Due to the prevalence of H2O and the importance of O2 in cell kill we
believe most damage results from _____ effect.
oxygen enhancement ratio correct answers ______ _____ _____: dose hypoxic / dose
oxygenated This ratio is 3 to 1 for the clinical range of x-radiation
reproductive death correct answers _______ _____: the major effect of radiation on dividing
cells. Cells fail to produce viable progeny
, interphase death correct answers ______ ______: seen in non-dividing cells such as mature
nervous system or muscle tissues. Cells simply lose the ability to function and die...typically at
high doses of radiation.
fractionation correct answers ______: A tumor tends to outgrow its blood supply. By dividing the
total dose into a number of relatively small daily doses (fractions) the tumor is allowed to
reoxygenate. This also allows normal cells to repair PLD (potentially lethal damage)
therapeutic ratio correct answers _____ _____: Typically this determines the curability of a
lesion and the decision to treat. Defined as the Normal Tissue Tolerance / Tumor Control Dose.
Practically, the tumor control dose depends on the tissue of origin and the size of the tumor
Seminoma
Hodgkins Disease
Neuroblastoma
Wilms Tumor
Larynx
Squamous Cell less than 4cm correct answers what are some different types of radiocurable
tumors?
3500-6000 rads correct answers what exposure dose is typically used for radiocurable tumors?
6000-7500 correct answers Size typically greater than 2cm but less than 4cm with cureative
doses of ____-______rads
Oral Cavity
Pharynx
Bladder
Cervix & Uterus
Ovary
