NR565- Advance Pharmacology Exam
2025-2026 Questions And Answers
CDC Guiding principles for prescribing opioids - ANSWER>>Opioids are not first-line
therapy
Establish goals for pain and function
Discuss risks and benefits
Use immediate-release opioids when starting
Use the lowest effective dose
Prescribe short durations for acute pain
Evaluate benefits and harms frequently
Use strategies to migrate risk
Review PDMP data
Use urine drug testing
Avoid concurrent opioid and benzo prescribing
Offer treatment for opioid use disorder
Examples of pure opioid agonists - ANSWER>>morphine methadone
fentanyl heroin oxycodone hydrocodone
opium
What is used to calculate a patient's overdose risk? - ANSWER>>total morphine
milligram equivalent (MME) per day to help assess the patient's overdose risk. If it is
high (≥50 MME/day and especially ≥90 MME/day)
How would you know when to refer someone to a pain specialist for pain management?
>>required for patients who take 120 mme per day of morphine milligram
ANSWER
equivalents
-
Prescription Drug Monitoring Program (PDMP)
o What is it?
o Why is it important? - >>Electronic databases enable providers to access
ANSWER
information regarding a patient's prescription history of controlled substances.
identify those at risk for overdose
, How renal and hepatic function impact medication levels in the body -
ANSWER>>Patients with renal or hepatic insufficiency can experience greater peak
effects and longer duration of action for medications, thereby reducing the dose at
which respiratory depression and overdose may occur. Similarly, for patients ages 65
years and older, reduced renal function and medication clearance due to age can result
in a smaller therapeutic window between safe dosages and dosages associated with
respiratory depression and overdose.
How to assess someone for possible drug diversion - >>Urine test at
ANSWERleast
yearly
PDMP routinely
When
should >>wit
naloxone ANSWER h
be every
prescribed opioid
for a
patient? -
prescriptio
n
Behaviors that predict controlled substance addiction - >>chronic
pain
ANSWER
family history
other substance abuse
prescribed for long-term use
Schedule II drugs
o Rules around prescribing
>> Substances or chemicals are defined as drugs with a
high
2025-2026 Questions And Answers
CDC Guiding principles for prescribing opioids - ANSWER>>Opioids are not first-line
therapy
Establish goals for pain and function
Discuss risks and benefits
Use immediate-release opioids when starting
Use the lowest effective dose
Prescribe short durations for acute pain
Evaluate benefits and harms frequently
Use strategies to migrate risk
Review PDMP data
Use urine drug testing
Avoid concurrent opioid and benzo prescribing
Offer treatment for opioid use disorder
Examples of pure opioid agonists - ANSWER>>morphine methadone
fentanyl heroin oxycodone hydrocodone
opium
What is used to calculate a patient's overdose risk? - ANSWER>>total morphine
milligram equivalent (MME) per day to help assess the patient's overdose risk. If it is
high (≥50 MME/day and especially ≥90 MME/day)
How would you know when to refer someone to a pain specialist for pain management?
>>required for patients who take 120 mme per day of morphine milligram
ANSWER
equivalents
-
Prescription Drug Monitoring Program (PDMP)
o What is it?
o Why is it important? - >>Electronic databases enable providers to access
ANSWER
information regarding a patient's prescription history of controlled substances.
identify those at risk for overdose
, How renal and hepatic function impact medication levels in the body -
ANSWER>>Patients with renal or hepatic insufficiency can experience greater peak
effects and longer duration of action for medications, thereby reducing the dose at
which respiratory depression and overdose may occur. Similarly, for patients ages 65
years and older, reduced renal function and medication clearance due to age can result
in a smaller therapeutic window between safe dosages and dosages associated with
respiratory depression and overdose.
How to assess someone for possible drug diversion - >>Urine test at
ANSWERleast
yearly
PDMP routinely
When
should >>wit
naloxone ANSWER h
be every
prescribed opioid
for a
patient? -
prescriptio
n
Behaviors that predict controlled substance addiction - >>chronic
pain
ANSWER
family history
other substance abuse
prescribed for long-term use
Schedule II drugs
o Rules around prescribing
>> Substances or chemicals are defined as drugs with a
high
