NRSG 3420 Exam 1 With Correct
Answers A+Graded.
medical management of sickle cell anemia - CORRECT ANSWER✔✔hematopoietic stem cell transplant
j j j j j j j j j j j
(HSCT) - may cure SCD but is not readily available due to lack of compatible donors or due to severe organ
j j j j j j j j j j j j j j j j j j j j j
damage that may be already present in patient
j j j j j j j j
pharmacologic therapy: j
- hydroxyurea (increases levels of fetal hemoglobin decreasing formation of sickled cells)
j j j j j j j j j j j
- folic acid supplements (maintain the amount needed for increased erythropoiesis to counteract the effects
j j j j j j j j j j j j j j
of hemolysis)
j j
- infections are common and can lead to crisis: immunization
j j j j j j j j j
- transfusion therapy (caution with repeat blood transfusions - pt can develop antibodies to donor blood,
j j j j j j j j j j j j j j j
hemolytic transfusion reactions may mimic the s/sx of sickle cell crisis
j j j j j j j j j j j
- supportive therapy (pain management, aspirin, NSAIDS, PCA, hydration, oxygen therapy)
j j j j j j j j j j
,cancer & thrombocytopenia - CORRECT ANSWER✔✔many chemotherapy agents cause some degree of
j j j j j j j j j j j
myelosuppression (depression of bone marrow function), resulting in:
j j j j j j j j j
- leukopenia
j
- neutropenia
j
- anemia
j
- thrombocytopenia
j
- increased r/o infection and bleeding
j j j j j
is predictable:
j
- pts usually reach point at which blood counts are lowest 7 to 14 days after chemo
j j j j j j j j j j j j j j j j
- during 2 weeks, nurses anticipate associated toxicities, especially a fever associated with neutrophil count
j j j j j j j j j j j j j j
less than 1500 cells/mm3
j j j j
- frequent monitoring of CBC is essential
j j j j j j
- pts are educated on strategies to protect against infection, injury, and blood loss
j j j j j j j j j j j j j
- erythropoetin (EPO) stimulated RBC production, decreasing the symptoms of treatment-induced chronic
j j j j j j j j j j j
anemia and reducing the need for blood transfusions
j j j j j j j j
- interleukin 11 (IL-11) (oprelvekin) stimulates the production of megakaryocytes (precursors to platelets)
j j j j j j j j j j j j
and can be used to prevent and treat severe thrombocytopenia but has had limited use because of toxicities
j j j j j j j j j j j j j j j j j j
thrombocytopenia - CORRECT ANSWER✔✔abnormally low platelet levels j j j j j j j
<20,000 - petechiae, gingival bleeding, excessive menstrual bleeding, excessive bleeding after
j j j j j j j j j j
surgery/dental extractions
j j
<5,000 - fatal CNS, or GI hemorrhage
j j j j j j
, management of thrombocytopenia - CORRECT ANSWER✔✔treat underlying condition j j j j j j j
monitor for factors increasing risk of bleeding (elevated INR/PT/aPTT, decreased fibrinogen, use of
j j j j j j j j j j j j
medications)
j
assess for and instruct patient/family on s/sx of bleeding (petechiae, bleeding, decrease HgB/HcT, frank or
j j j j j j j j j j j j j j
occult blood in body fluids, altered mental status, tachycardia)
j j j j j j j j j
minimize risk of bleeding: j j j
- use soft toothbrush, electric razor for shaving, keep lips moisturized, maintain fluid intake of at least 3 L q24
j j j j j j j j j j j j j j j j j j j
hrs
j
- avoid rectal temp, avoid IM injections (use smallest needle possible)
j j j j j j j j j j
- apply direst pressure to venipuncture site for at least 5 min
j j j j j j j j j j j
- avoid aspirin
j j
- caution against forceful nose blowing
j j j j j
preventing hemorrhage post-op - CORRECT ANSWER✔✔hemorrhage is an uncommon yet serious
j j j j j j j j j j
complication of surgery that can result in hypovolemic shock and death.
j j j j j j j j j j j
patient presents with hypotension; rapid, thready pulse; disorientation; restlessness, oliguria; and cold, pale
j j j j j j j j j j j j
skin; concentrated urine; air hunger (looking to catch breath)
j j j j j j j j j
assessment and identification of at-risk individuals, monitoring
j j j j j j
nursing management of transfusion reactions - CORRECT ANSWER✔✔- stop the transfusion, maintain the IV
j j j j j j j j j j j j j
line with NS through new IV tubing (given at slow rate)
j j j j j j j j j j j
Answers A+Graded.
medical management of sickle cell anemia - CORRECT ANSWER✔✔hematopoietic stem cell transplant
j j j j j j j j j j j
(HSCT) - may cure SCD but is not readily available due to lack of compatible donors or due to severe organ
j j j j j j j j j j j j j j j j j j j j j
damage that may be already present in patient
j j j j j j j j
pharmacologic therapy: j
- hydroxyurea (increases levels of fetal hemoglobin decreasing formation of sickled cells)
j j j j j j j j j j j
- folic acid supplements (maintain the amount needed for increased erythropoiesis to counteract the effects
j j j j j j j j j j j j j j
of hemolysis)
j j
- infections are common and can lead to crisis: immunization
j j j j j j j j j
- transfusion therapy (caution with repeat blood transfusions - pt can develop antibodies to donor blood,
j j j j j j j j j j j j j j j
hemolytic transfusion reactions may mimic the s/sx of sickle cell crisis
j j j j j j j j j j j
- supportive therapy (pain management, aspirin, NSAIDS, PCA, hydration, oxygen therapy)
j j j j j j j j j j
,cancer & thrombocytopenia - CORRECT ANSWER✔✔many chemotherapy agents cause some degree of
j j j j j j j j j j j
myelosuppression (depression of bone marrow function), resulting in:
j j j j j j j j j
- leukopenia
j
- neutropenia
j
- anemia
j
- thrombocytopenia
j
- increased r/o infection and bleeding
j j j j j
is predictable:
j
- pts usually reach point at which blood counts are lowest 7 to 14 days after chemo
j j j j j j j j j j j j j j j j
- during 2 weeks, nurses anticipate associated toxicities, especially a fever associated with neutrophil count
j j j j j j j j j j j j j j
less than 1500 cells/mm3
j j j j
- frequent monitoring of CBC is essential
j j j j j j
- pts are educated on strategies to protect against infection, injury, and blood loss
j j j j j j j j j j j j j
- erythropoetin (EPO) stimulated RBC production, decreasing the symptoms of treatment-induced chronic
j j j j j j j j j j j
anemia and reducing the need for blood transfusions
j j j j j j j j
- interleukin 11 (IL-11) (oprelvekin) stimulates the production of megakaryocytes (precursors to platelets)
j j j j j j j j j j j j
and can be used to prevent and treat severe thrombocytopenia but has had limited use because of toxicities
j j j j j j j j j j j j j j j j j j
thrombocytopenia - CORRECT ANSWER✔✔abnormally low platelet levels j j j j j j j
<20,000 - petechiae, gingival bleeding, excessive menstrual bleeding, excessive bleeding after
j j j j j j j j j j
surgery/dental extractions
j j
<5,000 - fatal CNS, or GI hemorrhage
j j j j j j
, management of thrombocytopenia - CORRECT ANSWER✔✔treat underlying condition j j j j j j j
monitor for factors increasing risk of bleeding (elevated INR/PT/aPTT, decreased fibrinogen, use of
j j j j j j j j j j j j
medications)
j
assess for and instruct patient/family on s/sx of bleeding (petechiae, bleeding, decrease HgB/HcT, frank or
j j j j j j j j j j j j j j
occult blood in body fluids, altered mental status, tachycardia)
j j j j j j j j j
minimize risk of bleeding: j j j
- use soft toothbrush, electric razor for shaving, keep lips moisturized, maintain fluid intake of at least 3 L q24
j j j j j j j j j j j j j j j j j j j
hrs
j
- avoid rectal temp, avoid IM injections (use smallest needle possible)
j j j j j j j j j j
- apply direst pressure to venipuncture site for at least 5 min
j j j j j j j j j j j
- avoid aspirin
j j
- caution against forceful nose blowing
j j j j j
preventing hemorrhage post-op - CORRECT ANSWER✔✔hemorrhage is an uncommon yet serious
j j j j j j j j j j
complication of surgery that can result in hypovolemic shock and death.
j j j j j j j j j j j
patient presents with hypotension; rapid, thready pulse; disorientation; restlessness, oliguria; and cold, pale
j j j j j j j j j j j j
skin; concentrated urine; air hunger (looking to catch breath)
j j j j j j j j j
assessment and identification of at-risk individuals, monitoring
j j j j j j
nursing management of transfusion reactions - CORRECT ANSWER✔✔- stop the transfusion, maintain the IV
j j j j j j j j j j j j j
line with NS through new IV tubing (given at slow rate)
j j j j j j j j j j j