Exam 3 NU 641 with correct answers |\ |\ |\ |\ |\ |\
drugs used for parkinson's
|\ |\ |\
dopaminergic
anticholinergic
levodopa - how is it used and why combined with carbidopa
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
how used: as dopamine replacement in parkinsons undergoes
|\ |\ |\ |\ |\ |\ |\ |\
conversion to DA in brain and activates DA receptors. |\ |\ |\ |\ |\ |\ |\ |\
why: blocks destruction of levodopa in periphery to decrease
|\ |\ |\ |\ |\ |\ |\ |\ |\
amount of decarboxylation so more drug can enter CNS and
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
increase dopamine synthesis (ties up vitamin b 6)
|\ |\ |\ |\ |\ |\ |\
patient education levodopa
|\ |\
avoid high protein meals delays drug
|\ |\ |\ |\ |\
can have on/off period - tell MD
|\ |\ |\ |\ |\ |\
N/V common take with fruits/veggies
|\ |\ |\ |\
monitor cardiac s/s and renal/liver function
|\ |\ |\ |\ |\
psychosis see MD |\ |\
what can't you combined levodopa with?
|\ |\ |\ |\ |\
antipsychotics decrease effectiveness |\ |\
MAO increase toxicity
|\ |\
pramipexole - what is it used for? |\ |\ |\ |\ |\ |\
, - parkinsons as dopamine agonist in early stages of PD to
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
improve motor function and combined with levodopa in advance
|\ |\ |\ |\ |\ |\ |\ |\ |\
stages to reduce fluctuations of motor control
|\ |\ |\ |\ |\ |\
- restless leg syndrome
|\ |\ |\
SE pramipexole
|\
nausea, dizziness, somulence, insomnia, constipation,
|\ |\ |\ |\ |\
hallucinations, SLEEP ATTACKS & IMPULSE CONTROL DISORDERS |\ |\ |\ |\ |\ |\ |\
(screen for this) |\ |\
has less sleep attacks than other agents
|\ |\ |\ |\ |\ |\
what drug increases pramipexole levels?
|\ |\ |\ |\
cimetidine
what drug is used to treat n/v in apomorphine
|\ |\ |\ |\ |\ |\ |\ |\
trimethobenzamide (Tigan) 3 days before taking. Cannot combine |\ |\ |\ |\ |\ |\ |\
with other antimetics risk for postural hypotension and decrease
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
effectiveness of drug. |\ |\
what is apomorphine used for?
|\ |\ |\ |\
acute hypomobility during off episodes in advance PD given by
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
injection
apomorphine SE |\
Severe N/V |\
Hypotension
hyper sexuality |\
cholinesterase agents for ALZ |\ |\ |\
donzepil
galantamine
rivastigmine
which alz med is irreversible inhibition?
|\ |\ |\ |\ |\
drugs used for parkinson's
|\ |\ |\
dopaminergic
anticholinergic
levodopa - how is it used and why combined with carbidopa
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
how used: as dopamine replacement in parkinsons undergoes
|\ |\ |\ |\ |\ |\ |\ |\
conversion to DA in brain and activates DA receptors. |\ |\ |\ |\ |\ |\ |\ |\
why: blocks destruction of levodopa in periphery to decrease
|\ |\ |\ |\ |\ |\ |\ |\ |\
amount of decarboxylation so more drug can enter CNS and
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
increase dopamine synthesis (ties up vitamin b 6)
|\ |\ |\ |\ |\ |\ |\
patient education levodopa
|\ |\
avoid high protein meals delays drug
|\ |\ |\ |\ |\
can have on/off period - tell MD
|\ |\ |\ |\ |\ |\
N/V common take with fruits/veggies
|\ |\ |\ |\
monitor cardiac s/s and renal/liver function
|\ |\ |\ |\ |\
psychosis see MD |\ |\
what can't you combined levodopa with?
|\ |\ |\ |\ |\
antipsychotics decrease effectiveness |\ |\
MAO increase toxicity
|\ |\
pramipexole - what is it used for? |\ |\ |\ |\ |\ |\
, - parkinsons as dopamine agonist in early stages of PD to
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
improve motor function and combined with levodopa in advance
|\ |\ |\ |\ |\ |\ |\ |\ |\
stages to reduce fluctuations of motor control
|\ |\ |\ |\ |\ |\
- restless leg syndrome
|\ |\ |\
SE pramipexole
|\
nausea, dizziness, somulence, insomnia, constipation,
|\ |\ |\ |\ |\
hallucinations, SLEEP ATTACKS & IMPULSE CONTROL DISORDERS |\ |\ |\ |\ |\ |\ |\
(screen for this) |\ |\
has less sleep attacks than other agents
|\ |\ |\ |\ |\ |\
what drug increases pramipexole levels?
|\ |\ |\ |\
cimetidine
what drug is used to treat n/v in apomorphine
|\ |\ |\ |\ |\ |\ |\ |\
trimethobenzamide (Tigan) 3 days before taking. Cannot combine |\ |\ |\ |\ |\ |\ |\
with other antimetics risk for postural hypotension and decrease
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
effectiveness of drug. |\ |\
what is apomorphine used for?
|\ |\ |\ |\
acute hypomobility during off episodes in advance PD given by
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
injection
apomorphine SE |\
Severe N/V |\
Hypotension
hyper sexuality |\
cholinesterase agents for ALZ |\ |\ |\
donzepil
galantamine
rivastigmine
which alz med is irreversible inhibition?
|\ |\ |\ |\ |\
