8/17/25, 11:28 AM Maryville - Nurs 615 Pharm Exam 1 - EXAM Questions & Answers | 100% Verified solutions |Questions with Correct Answers 2025…
Maryville - Nurs 615 Pharm Exam 1 - EXAM
Questions & Answers | 100% Verified solutions
|Questions with Correct Answers 2025 latest
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Terms in this set (147)
How does Low albumin = more free drug (bc the drug can't bind
hypoalbuminemia affect to albumin aka protein) = increased adverse effects
the process of
prescribing?
What is a Black Box is considered a contraindication to administer that
Warning: drug.
Half-life specifically means the amount of time it takes
What is the drugs half-life? for an administered drug to be halfway cleared from
the system.
the time between drug administration and maximum
Peak of action: concentration of drug in the blood stream. Best
therapeutic effect.
the time between onset of action and metabolism of
Duration of action: drug below the minimum needed for an effect. The
length of time you have the drug in your system.
According to the WHO The first step is to define the patient's problem
what is the first step in the
prescribing process?
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,8/17/25, 11:28 AM Maryville - Nurs 615 Pharm Exam 1 - EXAM Questions & Answers | 100% Verified solutions |Questions with Correct Answers 2025…
The second step is to specify the therapeutic objective
The third step is to choose which drug or treatment is needed.
Step 4 of the WHO Start the treatment
approach:
Step 5 of the WHO Educate the patient
approach:
Step 6 of the WHO Monitor the treatment
approach:
Phase 1 of drug The drug is tested on healthy volunteers
development:
Phase 2 of drug trials with people who have the disease for which the
development: drug is thought to be effective
Large numbers of patients in medical research centers
receive the drug in phase 3. This larger sampling
Phase 3 of drug
provides information about infrequent or rare adverse
development:
effects. The FFA will approve a new drug application if
phase 3 studies are satisfactory.
This phase is voluntary and involves postmarket
surveillance of the drug's therapeutic effects at the
completion of phase 3. The pharmaceutical company
Phase 4 of drug receives reports from doctors and other health care
development: professionals about the therapeutic results and
adverse effects of the drug. Some medications, for
example, have been found to be toxic and have been
removed from the market after their initial release.
much of the drug is lost in the absorption process.
Explain first pass
The liver metabolizes many drugs, thus reduces the
metabolism
bioavailabilty of the drug.
What is the fasted route of The fastest route of absorption is inhalation, and not
absorption: as mistakenly considered the IV administration.
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, 8/17/25, 11:28 AM Maryville - Nurs 615 Pharm Exam 1 - EXAM Questions & Answers | 100% Verified solutions |Questions with Correct Answers 2025…
The GI tract is lined with epithelial cells; drugs must
Why does the GI tract take
permeate through these cells in order to be absorbed
longer to absorb?
into the circulatory system.
the cell membrane. Cell membranes are essentially
What is One particular lipid bilayers which form a semipermeable membrane.
cellular barrier that may Pure lipid bilayers are generally permeable only to
prevent absorption of a small and uncharged solutes, hence whether or not a
given drug? molecule is ionized will affect its absorption, since
ionic molecules are charged.
Solubility favors charged species, permeability favors
neutral species. Some molecules have special
What is solubility?
exchange proteins and channels to facilitate
movement from the lumen into the circulation.
Why does absorption Absorption occurs at a slower rate because the
occur at a slower rate for complex membrane systems of GI mucosal layers,
oral, IM, SQ routes? muscle, and skin delay drug passage.
whether the drug is water or lipid (fat) soluble. Lipid-
The ability of a drug to
soluble drugs easily cross through cell membranes;
cross a cell membrane
water-soluble drugs can't. Lipid-soluble drugs can
depends on:
also cross the blood-brain barrier and enter the brain.
proteins such as the plasma protein albumin. The drug
can remain free or bind to the protein. The portion of
As a drug travels through a drug that's bound to a protein is inactive and can't
the body, it comes in exert a therapeutic effect. Only the free, or unbound,
contact with? portion remains active. A drug is said to be highly
protein-bound if more than 80% of the drug is bound
to protein.
Identify drug metabolism CYPs are the are the major enzymes involved in drug
and the role of metabolism accounting for about 75% of the total
isoenzymes in the p450 metabolism.
system
https://quizlet.com/1066193972/maryville-nurs-615-pharm-exam-1-exam-questions-answers-100-verified-solutions-questions-with-correct-answers-2… 3/20
Maryville - Nurs 615 Pharm Exam 1 - EXAM
Questions & Answers | 100% Verified solutions
|Questions with Correct Answers 2025 latest
update!!
Save
Terms in this set (147)
How does Low albumin = more free drug (bc the drug can't bind
hypoalbuminemia affect to albumin aka protein) = increased adverse effects
the process of
prescribing?
What is a Black Box is considered a contraindication to administer that
Warning: drug.
Half-life specifically means the amount of time it takes
What is the drugs half-life? for an administered drug to be halfway cleared from
the system.
the time between drug administration and maximum
Peak of action: concentration of drug in the blood stream. Best
therapeutic effect.
the time between onset of action and metabolism of
Duration of action: drug below the minimum needed for an effect. The
length of time you have the drug in your system.
According to the WHO The first step is to define the patient's problem
what is the first step in the
prescribing process?
https://quizlet.com/1066193972/maryville-nurs-615-pharm-exam-1-exam-questions-answers-100-verified-solutions-questions-with-correct-answers-2… 1/20
,8/17/25, 11:28 AM Maryville - Nurs 615 Pharm Exam 1 - EXAM Questions & Answers | 100% Verified solutions |Questions with Correct Answers 2025…
The second step is to specify the therapeutic objective
The third step is to choose which drug or treatment is needed.
Step 4 of the WHO Start the treatment
approach:
Step 5 of the WHO Educate the patient
approach:
Step 6 of the WHO Monitor the treatment
approach:
Phase 1 of drug The drug is tested on healthy volunteers
development:
Phase 2 of drug trials with people who have the disease for which the
development: drug is thought to be effective
Large numbers of patients in medical research centers
receive the drug in phase 3. This larger sampling
Phase 3 of drug
provides information about infrequent or rare adverse
development:
effects. The FFA will approve a new drug application if
phase 3 studies are satisfactory.
This phase is voluntary and involves postmarket
surveillance of the drug's therapeutic effects at the
completion of phase 3. The pharmaceutical company
Phase 4 of drug receives reports from doctors and other health care
development: professionals about the therapeutic results and
adverse effects of the drug. Some medications, for
example, have been found to be toxic and have been
removed from the market after their initial release.
much of the drug is lost in the absorption process.
Explain first pass
The liver metabolizes many drugs, thus reduces the
metabolism
bioavailabilty of the drug.
What is the fasted route of The fastest route of absorption is inhalation, and not
absorption: as mistakenly considered the IV administration.
https://quizlet.com/1066193972/maryville-nurs-615-pharm-exam-1-exam-questions-answers-100-verified-solutions-questions-with-correct-answers-2… 2/20
, 8/17/25, 11:28 AM Maryville - Nurs 615 Pharm Exam 1 - EXAM Questions & Answers | 100% Verified solutions |Questions with Correct Answers 2025…
The GI tract is lined with epithelial cells; drugs must
Why does the GI tract take
permeate through these cells in order to be absorbed
longer to absorb?
into the circulatory system.
the cell membrane. Cell membranes are essentially
What is One particular lipid bilayers which form a semipermeable membrane.
cellular barrier that may Pure lipid bilayers are generally permeable only to
prevent absorption of a small and uncharged solutes, hence whether or not a
given drug? molecule is ionized will affect its absorption, since
ionic molecules are charged.
Solubility favors charged species, permeability favors
neutral species. Some molecules have special
What is solubility?
exchange proteins and channels to facilitate
movement from the lumen into the circulation.
Why does absorption Absorption occurs at a slower rate because the
occur at a slower rate for complex membrane systems of GI mucosal layers,
oral, IM, SQ routes? muscle, and skin delay drug passage.
whether the drug is water or lipid (fat) soluble. Lipid-
The ability of a drug to
soluble drugs easily cross through cell membranes;
cross a cell membrane
water-soluble drugs can't. Lipid-soluble drugs can
depends on:
also cross the blood-brain barrier and enter the brain.
proteins such as the plasma protein albumin. The drug
can remain free or bind to the protein. The portion of
As a drug travels through a drug that's bound to a protein is inactive and can't
the body, it comes in exert a therapeutic effect. Only the free, or unbound,
contact with? portion remains active. A drug is said to be highly
protein-bound if more than 80% of the drug is bound
to protein.
Identify drug metabolism CYPs are the are the major enzymes involved in drug
and the role of metabolism accounting for about 75% of the total
isoenzymes in the p450 metabolism.
system
https://quizlet.com/1066193972/maryville-nurs-615-pharm-exam-1-exam-questions-answers-100-verified-solutions-questions-with-correct-answers-2… 3/20
