2025-2026
consuming recommended amounts of calcium and Vit D/ monitor levels - Answers General
teaching related to osteoporosis
daily weight-bearing exercises - Answers General teaching related to osteoporosis
Bone Density testing - Answers General teaching related to osteoporosis
raloxifene (Evista) - Answers Prototype(s) of SERMS- Selective Estrogen Receptor Modulators
tamoxifen - Answers Prototype(s) of SERMS- Selective Estrogen Receptor Modulators
When estrogen levels decrease in menopause, osteoclast activity (bone destroyers) increase.
Supplementing estrogen can help but will increase risk of cancers of breast and endometrium.
The SERMS are similar by activating estrogen receptors but do not provide extra estrogen -
Answers MOA for raloxifene (Evista); tamoxifen
Prevention and Tx of Postmenopausal Osteoporosis (female only) - Answers Appropriate
therapeutic use for raloxifene (Evista); tamoxifen
Also used for estrogen dependent breast CA (usually tamoxifen) - Answers Appropriate
therapeutic use for raloxifene (Evista); tamoxifen
AE: PE, DVT, occ. menopausal type sx (hot flashes): - Answers Nursing implication of raloxifene
(Evista); tamoxifen
Monitor clotting (SOB, chest, pain, tachycardia, leg pain) - Answers Nursing implication of
raloxifene (Evista); tamoxifen
Contraindicated with any hx of PE, DVT, or patients at risk for MI/CVA - Answers Nursing
implication of raloxifene (Evista); tamoxifen
Increased risk for endometrial cancer and blood clots, induces hot flashes - Answers Nursing
implication of tamoxifen
Pregnancy Category X - Answers Nursing implication of raloxifene (Evista); tamoxifen
alendronate (Fosamax) - Answers Prototype(s) of Biphosphonates "-dronate"
risedronate (Actonel) - Answers Prototype(s) of Biphosphonates "-dronate"
ibandronate (Boniva) - Answers Prototype(s) of Biphosphonates "-dronate"
↓ bone reabsorption by decreasing ↓ osteoclasts - Answers MOA for alendronate (Fosamax),
risedronate (Actonel, bandronate (Boniva)