TEST BANK FOR d d
Evolutionary Analysis 5th Edition by Herron Jon; Freeman Scott ISBN 9780321998378
d d d d d d d d d d
Chapter 1-20
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Chapter 1 d d d A Case for Evolutionary Thinking: Understanding HIV
d d d d d d
1) In which of the following regions has AIDS killed the largest number of individuals?
d d d d d d d d d d d d d
A) India
B) Sub-Saharan Africa d
C) United States d
D) China
E) United Kingdom d
Answer: B
d d
dSection: 1.1 d
Skill: Knowledge/Comprehension
d
2) The HIV virus contains all of the following components except
d d d d d d d d d d .
A) integrase
B) double-stranded RNA d
C) single-stranded RNA d
D) reverse transcriptase d
E) protease
Answer: B
d d
Section:
d
d1.1
Skill: Knowledge/Comprehension
d
3) The acronym HIV stands for which of the following?
d d d d d d d d
A) human intercellular virusd d
B) human immune virus d d
C) human immunodeficiency virus
d d
D) human immunity virus d d
E) human immunodeficiency vector
d d
Answer: C
d d
Section: 1.1 d
Skill: Knowledge/Comprehension
d
4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
d d d d d d d d d d d d
A) RNA polymerase d
B) reverse transcriptase d
C) DNA polymerase
d
D) reverse integrase d
E) RNA duplicased
Answer: B
d d
Section: 1.1
d d
Skill: Knowledge/Comprehension
d
1
Copyright © 2014 Pearson Education, Inc.
d d d d d
,5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On what
d d d d d d d d d d d d d d d d d
type of cells are these proteins typically observed?
d d d d d d d d
A) plasma cells d
B) dendritic cells d
C) effector helper T cells d d d
D) memory helper T cells d d d
E) both C and D d d d
Answer: E
d d
Section: 1.1
d d
Skill: Knowledge/Comprehension
d
6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the blood
d d d d d d d d d d d d d d d d
drops below what concentration?
d d d d
A) 2,000 cells per cubic millimeter
d d d d
B) 1,000 cells per cubic millimeter
d d d d
C) 500 cells per cubic millimeter
d d d d
D) 200 cells per cubic millimeter
d d d d
E) No CD4 T cells are observed.
d d d d d
Answer: D
d d
Section: 1.1 d
Skill: Knowledge/Comprehension
d
7) Which of the following drug categories are used to treat HIV infections?
d d d d d d d d d d d
A) integrase inhibitors d
B) protease inhibitors d
C) reverse transcriptase inhibitors d d
D) DNAse inhibitors d
E) fusion inhibitors d
Answer: D
d d
Section: 1.2
d d
Skill: Knowledge/Comprehension
d
8) Coreceptor inhibitors block HIV infection by preventing which of the following?
d d d d d d d d d d
A) binding of the HIV virion onto the plasma membrane
d d d d d d d d
B) binding of the HIV virion onto the CCR5 receptor
d d d d d d d d
C) binding of the HIV virion onto the gp120 protein
d d d d d d d d
D) degrading the coreceptor so the virion cannot attach d d d d d d d
E) binding of the HIV virion onto the CD4 receptor
d d d d d d d d
Answer: B
d d
Section: 1.2 d
Skill: Application/Analysis
d
9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
d d d d d d d d d d d d
A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell
d d d d d d d d d d d d d d d d d d
B) does not appear on the surface of CD4 T cells
d d d d d d d d d
C) appears on the surface of the CD4 T cells and inactivates the virion upon binding
d d d d d d d d d d d d d d
D) interferes with binding of the virion to the CD4 receptor protein
d d d d d d d d d d
2
Copyright © 2014 Pearson Education, Inc. d d d d d
,E) appears on the surface of the CD4 T cells and causes the virion to lyse upon binding
d d d d d d d d d d d d d d d d
Answer: B
d d
Section: 1.3 d
Skill: Application/Analysis
d
10) The ∆32 allele of CCR5 is found at the highest frequency in which of the following
d d d d d d d d d d d d d d d
populations?
d
A) Africans
B) Japanese
C) North Americans d
D) Europeans
E) South Americans d
Answer: D
d d
dSection: 1.3 d
Skill: Knowledge/Comprehension
d
11) HIV-1 is believed to have been transmitted to humans from which of the following
d d d d d d d d d d d d d
organisms?
d
A) gorillas
B) sooty mangabeys d
C) African green monkeys d d
D) chimpanzees
E) baboons
Answer: D
d d
Section:
d
d1.4
Skill: Knowledge/Comprehension
d
12) HIV-1 Group M is responsible for 95% of human infections. When is it estimated that HIV-1
d d d d d d d d d d d d d d d
Group M was transferred to humans?
d d d d d d
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer: C d
Section:
d
d1.4
Skill: Knowledge/Comprehension
d
13) Antibodies and killer T cells recognize HIV or HIV-infected cells by binding to short pieces
d d d d d d d d d d d d d d
of viral proteins displayed on the virus or the infected host cell. These short pieces of viral
d d d d d d d d d d d d d d d d d
proteins are called
d d . d d
A) coat proteinsd
B) virosomes
C) proteosomes
D) epitopes
3
Copyright © 2014 Pearson Education, Inc.
d d d d d
, E) episomes
Answer: D
d d
4
Copyright © 2014 Pearson Education, Inc.
d d d d d
Evolutionary Analysis 5th Edition by Herron Jon; Freeman Scott ISBN 9780321998378
d d d d d d d d d d
Chapter 1-20
d d
Chapter 1 d d d A Case for Evolutionary Thinking: Understanding HIV
d d d d d d
1) In which of the following regions has AIDS killed the largest number of individuals?
d d d d d d d d d d d d d
A) India
B) Sub-Saharan Africa d
C) United States d
D) China
E) United Kingdom d
Answer: B
d d
dSection: 1.1 d
Skill: Knowledge/Comprehension
d
2) The HIV virus contains all of the following components except
d d d d d d d d d d .
A) integrase
B) double-stranded RNA d
C) single-stranded RNA d
D) reverse transcriptase d
E) protease
Answer: B
d d
Section:
d
d1.1
Skill: Knowledge/Comprehension
d
3) The acronym HIV stands for which of the following?
d d d d d d d d
A) human intercellular virusd d
B) human immune virus d d
C) human immunodeficiency virus
d d
D) human immunity virus d d
E) human immunodeficiency vector
d d
Answer: C
d d
Section: 1.1 d
Skill: Knowledge/Comprehension
d
4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
d d d d d d d d d d d d
A) RNA polymerase d
B) reverse transcriptase d
C) DNA polymerase
d
D) reverse integrase d
E) RNA duplicased
Answer: B
d d
Section: 1.1
d d
Skill: Knowledge/Comprehension
d
1
Copyright © 2014 Pearson Education, Inc.
d d d d d
,5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On what
d d d d d d d d d d d d d d d d d
type of cells are these proteins typically observed?
d d d d d d d d
A) plasma cells d
B) dendritic cells d
C) effector helper T cells d d d
D) memory helper T cells d d d
E) both C and D d d d
Answer: E
d d
Section: 1.1
d d
Skill: Knowledge/Comprehension
d
6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the blood
d d d d d d d d d d d d d d d d
drops below what concentration?
d d d d
A) 2,000 cells per cubic millimeter
d d d d
B) 1,000 cells per cubic millimeter
d d d d
C) 500 cells per cubic millimeter
d d d d
D) 200 cells per cubic millimeter
d d d d
E) No CD4 T cells are observed.
d d d d d
Answer: D
d d
Section: 1.1 d
Skill: Knowledge/Comprehension
d
7) Which of the following drug categories are used to treat HIV infections?
d d d d d d d d d d d
A) integrase inhibitors d
B) protease inhibitors d
C) reverse transcriptase inhibitors d d
D) DNAse inhibitors d
E) fusion inhibitors d
Answer: D
d d
Section: 1.2
d d
Skill: Knowledge/Comprehension
d
8) Coreceptor inhibitors block HIV infection by preventing which of the following?
d d d d d d d d d d
A) binding of the HIV virion onto the plasma membrane
d d d d d d d d
B) binding of the HIV virion onto the CCR5 receptor
d d d d d d d d
C) binding of the HIV virion onto the gp120 protein
d d d d d d d d
D) degrading the coreceptor so the virion cannot attach d d d d d d d
E) binding of the HIV virion onto the CD4 receptor
d d d d d d d d
Answer: B
d d
Section: 1.2 d
Skill: Application/Analysis
d
9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
d d d d d d d d d d d d
A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell
d d d d d d d d d d d d d d d d d d
B) does not appear on the surface of CD4 T cells
d d d d d d d d d
C) appears on the surface of the CD4 T cells and inactivates the virion upon binding
d d d d d d d d d d d d d d
D) interferes with binding of the virion to the CD4 receptor protein
d d d d d d d d d d
2
Copyright © 2014 Pearson Education, Inc. d d d d d
,E) appears on the surface of the CD4 T cells and causes the virion to lyse upon binding
d d d d d d d d d d d d d d d d
Answer: B
d d
Section: 1.3 d
Skill: Application/Analysis
d
10) The ∆32 allele of CCR5 is found at the highest frequency in which of the following
d d d d d d d d d d d d d d d
populations?
d
A) Africans
B) Japanese
C) North Americans d
D) Europeans
E) South Americans d
Answer: D
d d
dSection: 1.3 d
Skill: Knowledge/Comprehension
d
11) HIV-1 is believed to have been transmitted to humans from which of the following
d d d d d d d d d d d d d
organisms?
d
A) gorillas
B) sooty mangabeys d
C) African green monkeys d d
D) chimpanzees
E) baboons
Answer: D
d d
Section:
d
d1.4
Skill: Knowledge/Comprehension
d
12) HIV-1 Group M is responsible for 95% of human infections. When is it estimated that HIV-1
d d d d d d d d d d d d d d d
Group M was transferred to humans?
d d d d d d
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer: C d
Section:
d
d1.4
Skill: Knowledge/Comprehension
d
13) Antibodies and killer T cells recognize HIV or HIV-infected cells by binding to short pieces
d d d d d d d d d d d d d d
of viral proteins displayed on the virus or the infected host cell. These short pieces of viral
d d d d d d d d d d d d d d d d d
proteins are called
d d . d d
A) coat proteinsd
B) virosomes
C) proteosomes
D) epitopes
3
Copyright © 2014 Pearson Education, Inc.
d d d d d
, E) episomes
Answer: D
d d
4
Copyright © 2014 Pearson Education, Inc.
d d d d d
