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NURS 8024 Pharm Exam 3 (antimicrobial part 2) 2025 COMPLETE QUESTIONS With 100% Verified Solutions,

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NURS 8024 Pharm Exam 3 (antimicrobial part 2) 2025 COMPLETE QUESTIONS With 100% Verified Solutions,

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NURS 8024 Pharm Exam 3 (antimicrobial part 2) 2025
COMPLETE QUESTIONS With 100% Verified Solutions,
Bacterial protein synthesis inhibitors - (ANSWER)Clindamycin



Clindamycin - (ANSWER)Time dependent killing

Inhibits protein synthesis

Bacteriostatic

90% bioavailability



Clindamycin mechanism of resistance - (ANSWER)Altered target sites

Active efflux (pushes drug out of the cell)



Clindamycin ADE - (ANSWER)GI upset

Skin rash

Neutropenia

Superinfections such a c diff pseudomembranous

- don't use if patient has history of c diff



Clindamycin indications - (ANSWER)Gram positive

Prophylaxis of endocarditis in valve patients with PCN allergy



Oxazolidinones - (ANSWER)New class of bacterial protein synthesis inhibitors

, Time dependent killing

Prevents formation of ribosome complex

Bacteriostatic & Bactericidal against strep



Linezolid - (ANSWER)Protein synthesis inhibitor

100% bioavailability orally

30% CSF penetration



Linezolid ADE - (ANSWER)Hematologic

Increased thrombocytopenia risk

Anemia, neutropenia, neuropathy

Optic & peripheral neuropathy

Serotonin syndrome with SSRIs



Linezolid Indications - (ANSWER)Gram positive resistant

VRE, HCAP, CAP

Complicated skin & tissue infections

Off label use for TB

No resistance currently



Fluoroquinolones - (ANSWER)Norfloxacin (1st gen)

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