Page | 1
COMLEX Level 1 Questions with Detailed
Verified Answers
cysteine stone
⼀Answer:- - *Hexagonal* stones
- *Ground, glass appearance*
- *(+) urinary cyanide nitroprusside test
- Defect in renal transport of COLA: Cysteine, Ornithine, Lysine,
Arginine
- Does NOT respond to shock wave therapy
angiodysplasia
⼀Answer:- most common cause of lower GI bleeding in pt's >60
superior mesenteric artery
⼀Answer:- supplies the lower portion of the duodenum, jejunum,
ileum, cecum, ascending colon, and transverse colon to the splenic
flexure
pancreatic cancer
, Page | 2
⼀Answer:- -usually arises in the *head* of the pancreas
-is associated with *jaundice and pain* due to obstruction of the
common bile duct
- it is the *4th* most common cause of cancer
-has a very poor prognosis
1. Calcium channel blockers--> specifically smooth muscle
antagonists--> SM dilation
2. Alpha adrenergic receptor blockers --> cause dilation of vessels
instead of constriction
3. Beta 2 agonists: causes dilation of smooth muscle vessels
⼀Answer:- Patients with GERD normally have a dysfunction with LES
sphincter tone that allows acid to reflux into the esophagus, thus drugs
that affect sphincter tone would make GERD worse. What are the
name of three drug categories that do this?
celiac disease
⼀Answer:- malabsorption syndrome caused by an immune reaction
to gliadian protein in gluten
-Tissue transglutaminase
-results in villous atrophy of small intestine mucosa and causes
steatorrhea, diarrhea, bloating and abdominal pain
-*also associated with other autoimmune disorders like hashimotos
thyroiditis*
make NPO, Place on an NG tube and suction obstruction out-->
this will usually resolve obstruction
, Page | 3
⼀Answer:- after a patient comes to the ER with sudden onset of
pain and abdominal distention W/O peritoneal signs and after x-ray
you diagnose her with a small bowel obstruction. What do you do
next?
Low total calcium due to low albumin levels from cirrhosis (95%
of Ca2+ is bound to albumin) and normal ionized Ca2+ because
PTH regulates free ionized Ca2+ independently--> that is why
there are no signs go hypocalcemia
⼀Answer:- In a patient with liver cirrhosis what calcium levels would
you expect to see?
Would there be signs of hypocalcemia--> tetany, paresthesias,
abdominal cramps?
T5-T11
⼀Answer:- where would you find a viserosomatic reflex resulting in
placatory changes of the pancreas?
Deferoxamine (Desferal)
⼀Answer:- iron chelating agent used in the treatment of iron
intoxication
short leg syndrome
⼀Answer:- when a patient presents with a flexible scoliotic curve it
is important to evaluate for...
inferior trunk--> encompasses broadmann areas 22,39,40 which
are in the temporal region
, Page | 4
⼀Answer:- Infarct to what trunk of the Left MCA results in
Wernicke's aphasia?
Superior division--> encompasses brooks area, frontal eye field,
primary motor cortex and primary somatosensory cortex
⼀Answer:- Infarct to what trunk of the Left MCA results in Broca's
aphasia?
Osteosarcoma
⼀Answer:- bone tumor that is present in young adult males that
involves the metaphysis of the long bones
Ewing's sarcoma t(11;22)
⼀Answer:- bone tumor that is present in young adult males that
involves the *diaphysis(mid-shaft)* of the long bones.
fibrosarcoma
⼀Answer:- malignant fibroblasts within a collagenous matrix
chondrosarcoma
⼀Answer:- osseous sarcomas that affect older patients and has a
predilection for flat bones in the *shoulders and pelvis*
tyrosine, due to a defect in phenylalanine hydroxylase
⼀Answer:- PKU presents as failure to thrive, mental retardation,
gapped teeth, etc. What is the amino acid that needs to be
supplemented due to a defect in what enzyme?
Rib 2
COMLEX Level 1 Questions with Detailed
Verified Answers
cysteine stone
⼀Answer:- - *Hexagonal* stones
- *Ground, glass appearance*
- *(+) urinary cyanide nitroprusside test
- Defect in renal transport of COLA: Cysteine, Ornithine, Lysine,
Arginine
- Does NOT respond to shock wave therapy
angiodysplasia
⼀Answer:- most common cause of lower GI bleeding in pt's >60
superior mesenteric artery
⼀Answer:- supplies the lower portion of the duodenum, jejunum,
ileum, cecum, ascending colon, and transverse colon to the splenic
flexure
pancreatic cancer
, Page | 2
⼀Answer:- -usually arises in the *head* of the pancreas
-is associated with *jaundice and pain* due to obstruction of the
common bile duct
- it is the *4th* most common cause of cancer
-has a very poor prognosis
1. Calcium channel blockers--> specifically smooth muscle
antagonists--> SM dilation
2. Alpha adrenergic receptor blockers --> cause dilation of vessels
instead of constriction
3. Beta 2 agonists: causes dilation of smooth muscle vessels
⼀Answer:- Patients with GERD normally have a dysfunction with LES
sphincter tone that allows acid to reflux into the esophagus, thus drugs
that affect sphincter tone would make GERD worse. What are the
name of three drug categories that do this?
celiac disease
⼀Answer:- malabsorption syndrome caused by an immune reaction
to gliadian protein in gluten
-Tissue transglutaminase
-results in villous atrophy of small intestine mucosa and causes
steatorrhea, diarrhea, bloating and abdominal pain
-*also associated with other autoimmune disorders like hashimotos
thyroiditis*
make NPO, Place on an NG tube and suction obstruction out-->
this will usually resolve obstruction
, Page | 3
⼀Answer:- after a patient comes to the ER with sudden onset of
pain and abdominal distention W/O peritoneal signs and after x-ray
you diagnose her with a small bowel obstruction. What do you do
next?
Low total calcium due to low albumin levels from cirrhosis (95%
of Ca2+ is bound to albumin) and normal ionized Ca2+ because
PTH regulates free ionized Ca2+ independently--> that is why
there are no signs go hypocalcemia
⼀Answer:- In a patient with liver cirrhosis what calcium levels would
you expect to see?
Would there be signs of hypocalcemia--> tetany, paresthesias,
abdominal cramps?
T5-T11
⼀Answer:- where would you find a viserosomatic reflex resulting in
placatory changes of the pancreas?
Deferoxamine (Desferal)
⼀Answer:- iron chelating agent used in the treatment of iron
intoxication
short leg syndrome
⼀Answer:- when a patient presents with a flexible scoliotic curve it
is important to evaluate for...
inferior trunk--> encompasses broadmann areas 22,39,40 which
are in the temporal region
, Page | 4
⼀Answer:- Infarct to what trunk of the Left MCA results in
Wernicke's aphasia?
Superior division--> encompasses brooks area, frontal eye field,
primary motor cortex and primary somatosensory cortex
⼀Answer:- Infarct to what trunk of the Left MCA results in Broca's
aphasia?
Osteosarcoma
⼀Answer:- bone tumor that is present in young adult males that
involves the metaphysis of the long bones
Ewing's sarcoma t(11;22)
⼀Answer:- bone tumor that is present in young adult males that
involves the *diaphysis(mid-shaft)* of the long bones.
fibrosarcoma
⼀Answer:- malignant fibroblasts within a collagenous matrix
chondrosarcoma
⼀Answer:- osseous sarcomas that affect older patients and has a
predilection for flat bones in the *shoulders and pelvis*
tyrosine, due to a defect in phenylalanine hydroxylase
⼀Answer:- PKU presents as failure to thrive, mental retardation,
gapped teeth, etc. What is the amino acid that needs to be
supplemented due to a defect in what enzyme?
Rib 2
