NURS 5315 UTA EXAM 2|| ADVANCED PATHOPHYSIOLOGY UTA EXAM 2
2025
NURS 5315 UTA EXAM 2|| ADVANCED PATHOPHYSIOLOGY
UTA EXAM 2 ALL QUESTIONS AND CORRECT ANSWERS
ALREADY GRADED A+|| LATEST AND COMPLETE
VERSION 2024-2025 WITH VERIFIED SOLUTIONS||
ASSURED PASS!!
HIV EIA (3rd generation immunoassay) - ANSWER: can use urine, saliva, or
serum (most accurate), need to wait until 12 weeks post exposure to see
antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell - ANSWER: Cellular bags of granules located in loose connective
tisssue close to blood vessels. Activation initiates inflammatory process.
Histamine - ANSWER: Causes vasodilation, increases vascular permeability,
increases blood flow to the site of injury- causes erythema and swelling.
Cytokines - ANSWER: Soluble factors that contribute to the regulation of
innate or adaptive resistance by affecting other neighboring cells. Can be pro-
inflammatory or anti-inflammatory. Can react quickly or be more delayed.
Leukotrines - ANSWER: Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils, monocytes, and
eosinophils.target of inhibition for singular.
Prostaglandins - ANSWER: Released when mast cells degranulate, are
produced by the arachidonic pathway. Cause vasodilation, platelet aggregation
at site of injury, pain, and fever.
Chemotactic factors - ANSWER: Biochemical substance that attracts leukocyte
to the site of inflammation
1
, NURS 5315 UTA EXAM 2|| ADVANCED PATHOPHYSIOLOGY UTA EXAM 2
2025
Neutrophils - ANSWER: Predominant leukocyte at work during the early stages
of acute inflammation
Monocytes - ANSWER: Become macrophages when entering the tissue,
responsible for presenting antigens to the CD4 cell which triggers T-cell
immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function - ANSWER: Causes fever, activates phagocytes &
lymphocytes and also increases the release of IL6a
Cytokine IL6 function - ANSWER: Stimulates production of acute phase
reactants and promotes growth and stimulation of RBCs
Cytokine TNF function - ANSWER: Causes fever, increases synthesis of
proinflammatory proteins by liver, causes muscle wasting, induces thrombosis
Cytokine growth factor function - ANSWER: Promotes production and
maturation of neutrophils
Complement - ANSWER: Functions include bacterial lysis, vasodilation and
increased vascular permeability, triggers mast cell degranulation, chemotaxis,
and opsonization.
Kinin - ANSWER: Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and vasodilation.
Coagulation cascade - ANSWER: Factor XII activates kinin. Function is to
form fibrin mesh to stop bleeding and trap micro organisms.
COX1 - ANSWER: Prostaglandin of arachidonic pathway. Provides
gastroprotection, platelet aggregation, fluid/electrolyte balance
COX2 - ANSWER: Prostaglandin of arachidonic pathway. Responsible for
pain, fever, renal protection, tissue repair, reproduction development.
2
2025
NURS 5315 UTA EXAM 2|| ADVANCED PATHOPHYSIOLOGY
UTA EXAM 2 ALL QUESTIONS AND CORRECT ANSWERS
ALREADY GRADED A+|| LATEST AND COMPLETE
VERSION 2024-2025 WITH VERIFIED SOLUTIONS||
ASSURED PASS!!
HIV EIA (3rd generation immunoassay) - ANSWER: can use urine, saliva, or
serum (most accurate), need to wait until 12 weeks post exposure to see
antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell - ANSWER: Cellular bags of granules located in loose connective
tisssue close to blood vessels. Activation initiates inflammatory process.
Histamine - ANSWER: Causes vasodilation, increases vascular permeability,
increases blood flow to the site of injury- causes erythema and swelling.
Cytokines - ANSWER: Soluble factors that contribute to the regulation of
innate or adaptive resistance by affecting other neighboring cells. Can be pro-
inflammatory or anti-inflammatory. Can react quickly or be more delayed.
Leukotrines - ANSWER: Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils, monocytes, and
eosinophils.target of inhibition for singular.
Prostaglandins - ANSWER: Released when mast cells degranulate, are
produced by the arachidonic pathway. Cause vasodilation, platelet aggregation
at site of injury, pain, and fever.
Chemotactic factors - ANSWER: Biochemical substance that attracts leukocyte
to the site of inflammation
1
, NURS 5315 UTA EXAM 2|| ADVANCED PATHOPHYSIOLOGY UTA EXAM 2
2025
Neutrophils - ANSWER: Predominant leukocyte at work during the early stages
of acute inflammation
Monocytes - ANSWER: Become macrophages when entering the tissue,
responsible for presenting antigens to the CD4 cell which triggers T-cell
immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function - ANSWER: Causes fever, activates phagocytes &
lymphocytes and also increases the release of IL6a
Cytokine IL6 function - ANSWER: Stimulates production of acute phase
reactants and promotes growth and stimulation of RBCs
Cytokine TNF function - ANSWER: Causes fever, increases synthesis of
proinflammatory proteins by liver, causes muscle wasting, induces thrombosis
Cytokine growth factor function - ANSWER: Promotes production and
maturation of neutrophils
Complement - ANSWER: Functions include bacterial lysis, vasodilation and
increased vascular permeability, triggers mast cell degranulation, chemotaxis,
and opsonization.
Kinin - ANSWER: Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and vasodilation.
Coagulation cascade - ANSWER: Factor XII activates kinin. Function is to
form fibrin mesh to stop bleeding and trap micro organisms.
COX1 - ANSWER: Prostaglandin of arachidonic pathway. Provides
gastroprotection, platelet aggregation, fluid/electrolyte balance
COX2 - ANSWER: Prostaglandin of arachidonic pathway. Responsible for
pain, fever, renal protection, tissue repair, reproduction development.
2
