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Exam (elaborations)

Advanced Pathophysiology Exam 1 Review Guide – NURS 5315 (UTA, 2025)

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This document is a comprehensive exam review guide for NURS 5315 – Advanced Pathophysiology at UTA, focused on Exam 1 content for 2025. It includes certified multiple-choice questions with correct answers, covering key topics such as cellular adaptation, fluid and electrolyte balance, acid-base disorders, genetics, and mechanisms of disease.

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Nurs 5315 advanced pathophysiology uta exam 1 2025




NURS 5315 Advanced Pathophysiology UTA
Exam 1 2025 ; certified exam questions with
correct answers




Atrophy - Correct-answer-E. Cells decrease in size
P. Still functional
Physiologic: thymus gland in early childhood Pathological: disuse




Hypertrophy - Correct-answer-E. Increase in cell size
P. Increased workload Physiologic: weightlifting
Pathologic: cardiomegaly from HTN




Hyperplasia - Correct-answer-E. Increase in cell number
P. Increased cellular division Physiologic: liver regeneration




Pathologic: endometrial- usually r/t hormones




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,Nurs 5315 advanced pathophysiology uta exam 1 2025



Dysplasia - Correct-answer-E. Cells change in size, shape, organization
P. AKA atypical hyperplasia, a disorderly proliferation Physiologic: N/A
Pathologic: squamous dysplasia of cervix from HPV




Metaplasia - Correct-answer-E. one cell type replaced with another
P. reprogramming of stem cells, reversible Physiologic: N/A
Pathologic: stratified squamous cells in bronchial lining r/t cigarette smoke




Hypoxia injury - Correct-answer-E. inadequate oxygenation of tissues
P. decrease in mitochondrial function, decreased production of ATP increases
anaerobic metabolism. eventual cell death.
C.M. hypoxia, cyanosis, cognitive impairment, lethargy




Free radical and ROS - Correct-answer-E. normal byproduct of ATP production,
will overwhelm the mitochondria- exhaust intracellular antioxidants
P. lipid peroxidation, damage proteins, fragment DNA
C.M. development in Alzheimer's, heart disease, Parkinson's disease, Amyotrophic
Lateral Sclerosis




Ethanol - Correct-answer-E. mood altering drug, long term effects on liver and
nutritional status
P. metabolized by liver, generates free radicals

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, Nurs 5315 advanced pathophysiology uta exam 1 2025

C.M. CNS depression, nutrient deficiencies-Mag, Vit B6, thiamine, PO4,
inflammation and fatty infiltration of liver, hepatomegaly, leads to liver failure
irreversible




Oncosis - Correct-answer-Na and H2O enter cell and cause swelling. Organ
increases in weight, becomes distended and pale. Associated with high fever,
hypocalcemia, certain infections




Fatty Infiltration - Correct-answer-intracellular accumulation of lipids in the liver
liver fails to metabolize lipids. usually from ETOH or high fat diet. can lead to
cirrhosis




Hydrostatic pressure - Correct-answer-Blood pressure- pushes fluid outside of the
vessels, the force of fluid against the walls of a compartment- venous obstruction,
Na and water retention




Oncotic pressure - Correct-answer-Colloid pressure keeps water inside the
compartment, attracts water from interstitial space back into the capillary- losses or
diminished albumin




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