Ldst 120 Exam Revision Questions And Correct Answers

LFTI EXAM 2 QUESTIONS AND CORRECT
ANSWERS!!
Liver

- largest organ of the body
- receives dual blood supply (20% from hepatic artery, 80% from portal vein)

_______________ are the primary cells of the liver

hepatocytes (2/3 liver mass)

- Blood enters liver via the ______________ and drains through the _______________ of
the hepatic ____________.
- Bile flows in the _______________ direction

- enters via the portal triad
- drains through the sinusoidal space
- hepatic lobule
- opposite direction

Function of hepatocytes

- synthesis of serum proteins
- production of bile
- regulation of nutrients
- metabolism & conjugation of lipophilic compounds for excretion in bile or urine

What serum proteins do hepatocytes synthesize? (3)

- albumin
- coagulation factors (Protein C and S)
- growth factors

What do hepatocytes produce? (3)

, - bile acids
- cholesterol
- phospholipids

What processes do hepatocytes do to regulate nutrients?

- gluconeogenesis
- glycolysis
- lipogenesis

What kind of compounds undergo metabolism and conjugating for excretion in bile or
urine

- bilirubin
- urea

What are markers of hepatocellular function?

- serum bilirubin
- serum albumin
- coagulation factors-prothrombin time (INR)

Normal serum values of total bilirubin

0.3-1 mg/dL- comprised of direct and indirect bilirubin

Unconjugated (indirect) bilirubin

- insoluble in water, bound to albumin
- byproduct of heme degradation

What is elevation in indirect bilirubin typically due to?

other causes, such as hemolysis

Conjugated (direct) bilirubin

- water-soluble, excreted by kidney
- ULN= 0.3 mg/dL