NURS 5334 Pharm Final Exam Review[ACTUAL EXAM] LATEST
VERSION [QUESTIONS AND ANSWERS] WITH PRACTICE EXAM
DETAILED AND VERIFIED FOR GUARANTEED PASS- LATEST
UPDATE 2025 GRADED A
Lamotrigine and OCPs Interaction - CORRECT ANSWER OCPs can reduce
lamotrigine levels, requiring an increase in the dose of lamotrigine.
Tricyclic Antidepressants Caution - CORRECT ANSWER Should be prescribed
cautiously in patients with CAD.
Onset of Action Symptoms for SSRIs - CORRECT ANSWER Patients may feel a bit
of nausea, which resolves in about 1 week.
Pediatric Dosing Information - CORRECT ANSWER There is a lack of evidence-
based literature on the safe and effective use of medications in children.
Neonates and Protein-Bound Drugs - CORRECT ANSWER Protein binding is
decreased in neonates, increasing the amount of free drug available.
Adult Renal Function Age - CORRECT ANSWER Adult levels of renal function are
achieved at 12 months.
Beers List - CORRECT ANSWER A list that identifies drugs with a high likelihood of
causing adverse effects in the elderly.
Gastric Acidity in Pediatric Patients - CORRECT ANSWER Gastric acidity does not
reach adult values for 2 years.
Complications to Drug Therapy in the Elderly - CORRECT ANSWER Include altered
pharmacokinetics, multiple and severe illnesses, multiple-drug therapy, and poor
adherence.
Altered Absorption in the Elderly - CORRECT ANSWER May result in a delay in drug
response.
Factors Altering Drug Distribution in the Elderly - CORRECT ANSWER Include
increased body fat, decreased percentage of lean body mass, decreased total body
water, and reduced concentration of serum albumin.
Adverse Drug Reactions in the Elderly - CORRECT ANSWER The most important
cause of adverse drug reactions in the elderly is polypharmacy.
,Bupropion - CORRECT ANSWER An alternative medication that can be added to
help with erectile dysfunction caused by SSRIs.
Increased Seizure Activity with Ethosuximide - CORRECT ANSWER Ethosuximide
can induce seizures, so increased seizure activity should be monitored.
Renal Dysfunction Monitoring - CORRECT ANSWER Patients on ethosuximide
should be monitored for renal dysfunction.
Weight Gain with OCPs - CORRECT ANSWER OCPs can cause weight gain, which
may be a concern for patients taking lamotrigine.
Hepatotoxicity with Ethosuximide - CORRECT ANSWER Hepatotoxicity is a potential
risk, but uncommon.
Contraceptive Failure with OCPs - CORRECT ANSWER OCPs may lead to
contraceptive failure when interacting with lamotrigine.
Insomnia with SSRIs - CORRECT ANSWER Patients may experience insomnia for a
week after starting SSRIs.
FDA and Pediatric Dosing - CORRECT ANSWER The FDA does not require pediatric
dosing information for all medications.
Free Drug Availability in Neonates - CORRECT ANSWER Decreased protein binding
in neonates increases the amount of free drug available.
Proper index of renal function in the elderly - CORRECT ANSWER Creatinine
clearance or GFR.
Factors underlying increase in adverse reactions in geriatric population - CORRECT
ANSWER Polypharmacy, severe illness, multiple pathologies, greater use of drugs
that have a low therapeutic index, inadequate supervision, poor patient adherence.
Maximum amount of Sumatriptan that can be taken in 1 day - CORRECT ANSWER
200 mg.
Properties determining anesthetic penetration of axon membrane - CORRECT
ANSWER Molecular size, lipid solubility, degree of ionization at tissue pH.
Medication that will not cause rebound headaches from overuse - CORRECT
ANSWER Propranolol.
Best option for menstrual migraine - CORRECT ANSWER Low dose estrogen about
3 days prior to menses.
, Food that can trigger migraines - CORRECT ANSWER Hot dog.
Medication that is a Serotonin 1B1D receptor agonist - CORRECT ANSWER
Sumatriptan.
Side effect of Butterbur in migraine therapy - CORRECT ANSWER Liver damage.
Three main classes of opioid receptors - CORRECT ANSWER Mu, Kappa, Delta.
Reversal of effects caused by opioid agonists - CORRECT ANSWER Naloxone.
Medications used to treat OIC - CORRECT ANSWER Naloxegol, Methylinaltrexone,
Lubiprostone.
Definition of tolerance - CORRECT ANSWER Increased doses of a med needed to
obtain the same response.
Medication used for opioid abuse - CORRECT ANSWER Naltrexone.
Euphoria induced by morphine - CORRECT ANSWER An exaggerated sense of well-
being caused by the activation of mu receptors.
Medication given nasally for migraines - CORRECT ANSWER Butorphanol.
Mechanism of NSAIDs - CORRECT ANSWER Inhibition of the cyclo-oxygenase
enzyme.
Second generation Cox 2 inhibitors - CORRECT ANSWER Suppress inflammation
and cause less risk for gastric ulceration than Cox 1.
Glucocorticoids - CORRECT ANSWER Medications that should not be given with
ASA include Glucocorticoids.
Acetaminophen overdose treatment - CORRECT ANSWER The medication given for
acetaminophen overdose is Acetylcysteine.
Nonendocrine therapeutic uses for glucocorticoids - CORRECT ANSWER Uses
include RA, SLE, IBS, Bursitis, OA, Gout, and Disorders of the eye.
Prolonged use of glucocorticoids - CORRECT ANSWER The danger of prolonged
use is adrenal insufficiency.
Methotrexate toxicities - CORRECT ANSWER Methotrexate can cause fatal toxicities
of bone marrow, liver, kidneys, lungs, hemorrhagic enteritis, and GI perforation.
Etanercept monitoring - CORRECT ANSWER Jane should be checked for TB yearly.
VERSION [QUESTIONS AND ANSWERS] WITH PRACTICE EXAM
DETAILED AND VERIFIED FOR GUARANTEED PASS- LATEST
UPDATE 2025 GRADED A
Lamotrigine and OCPs Interaction - CORRECT ANSWER OCPs can reduce
lamotrigine levels, requiring an increase in the dose of lamotrigine.
Tricyclic Antidepressants Caution - CORRECT ANSWER Should be prescribed
cautiously in patients with CAD.
Onset of Action Symptoms for SSRIs - CORRECT ANSWER Patients may feel a bit
of nausea, which resolves in about 1 week.
Pediatric Dosing Information - CORRECT ANSWER There is a lack of evidence-
based literature on the safe and effective use of medications in children.
Neonates and Protein-Bound Drugs - CORRECT ANSWER Protein binding is
decreased in neonates, increasing the amount of free drug available.
Adult Renal Function Age - CORRECT ANSWER Adult levels of renal function are
achieved at 12 months.
Beers List - CORRECT ANSWER A list that identifies drugs with a high likelihood of
causing adverse effects in the elderly.
Gastric Acidity in Pediatric Patients - CORRECT ANSWER Gastric acidity does not
reach adult values for 2 years.
Complications to Drug Therapy in the Elderly - CORRECT ANSWER Include altered
pharmacokinetics, multiple and severe illnesses, multiple-drug therapy, and poor
adherence.
Altered Absorption in the Elderly - CORRECT ANSWER May result in a delay in drug
response.
Factors Altering Drug Distribution in the Elderly - CORRECT ANSWER Include
increased body fat, decreased percentage of lean body mass, decreased total body
water, and reduced concentration of serum albumin.
Adverse Drug Reactions in the Elderly - CORRECT ANSWER The most important
cause of adverse drug reactions in the elderly is polypharmacy.
,Bupropion - CORRECT ANSWER An alternative medication that can be added to
help with erectile dysfunction caused by SSRIs.
Increased Seizure Activity with Ethosuximide - CORRECT ANSWER Ethosuximide
can induce seizures, so increased seizure activity should be monitored.
Renal Dysfunction Monitoring - CORRECT ANSWER Patients on ethosuximide
should be monitored for renal dysfunction.
Weight Gain with OCPs - CORRECT ANSWER OCPs can cause weight gain, which
may be a concern for patients taking lamotrigine.
Hepatotoxicity with Ethosuximide - CORRECT ANSWER Hepatotoxicity is a potential
risk, but uncommon.
Contraceptive Failure with OCPs - CORRECT ANSWER OCPs may lead to
contraceptive failure when interacting with lamotrigine.
Insomnia with SSRIs - CORRECT ANSWER Patients may experience insomnia for a
week after starting SSRIs.
FDA and Pediatric Dosing - CORRECT ANSWER The FDA does not require pediatric
dosing information for all medications.
Free Drug Availability in Neonates - CORRECT ANSWER Decreased protein binding
in neonates increases the amount of free drug available.
Proper index of renal function in the elderly - CORRECT ANSWER Creatinine
clearance or GFR.
Factors underlying increase in adverse reactions in geriatric population - CORRECT
ANSWER Polypharmacy, severe illness, multiple pathologies, greater use of drugs
that have a low therapeutic index, inadequate supervision, poor patient adherence.
Maximum amount of Sumatriptan that can be taken in 1 day - CORRECT ANSWER
200 mg.
Properties determining anesthetic penetration of axon membrane - CORRECT
ANSWER Molecular size, lipid solubility, degree of ionization at tissue pH.
Medication that will not cause rebound headaches from overuse - CORRECT
ANSWER Propranolol.
Best option for menstrual migraine - CORRECT ANSWER Low dose estrogen about
3 days prior to menses.
, Food that can trigger migraines - CORRECT ANSWER Hot dog.
Medication that is a Serotonin 1B1D receptor agonist - CORRECT ANSWER
Sumatriptan.
Side effect of Butterbur in migraine therapy - CORRECT ANSWER Liver damage.
Three main classes of opioid receptors - CORRECT ANSWER Mu, Kappa, Delta.
Reversal of effects caused by opioid agonists - CORRECT ANSWER Naloxone.
Medications used to treat OIC - CORRECT ANSWER Naloxegol, Methylinaltrexone,
Lubiprostone.
Definition of tolerance - CORRECT ANSWER Increased doses of a med needed to
obtain the same response.
Medication used for opioid abuse - CORRECT ANSWER Naltrexone.
Euphoria induced by morphine - CORRECT ANSWER An exaggerated sense of well-
being caused by the activation of mu receptors.
Medication given nasally for migraines - CORRECT ANSWER Butorphanol.
Mechanism of NSAIDs - CORRECT ANSWER Inhibition of the cyclo-oxygenase
enzyme.
Second generation Cox 2 inhibitors - CORRECT ANSWER Suppress inflammation
and cause less risk for gastric ulceration than Cox 1.
Glucocorticoids - CORRECT ANSWER Medications that should not be given with
ASA include Glucocorticoids.
Acetaminophen overdose treatment - CORRECT ANSWER The medication given for
acetaminophen overdose is Acetylcysteine.
Nonendocrine therapeutic uses for glucocorticoids - CORRECT ANSWER Uses
include RA, SLE, IBS, Bursitis, OA, Gout, and Disorders of the eye.
Prolonged use of glucocorticoids - CORRECT ANSWER The danger of prolonged
use is adrenal insufficiency.
Methotrexate toxicities - CORRECT ANSWER Methotrexate can cause fatal toxicities
of bone marrow, liver, kidneys, lungs, hemorrhagic enteritis, and GI perforation.
Etanercept monitoring - CORRECT ANSWER Jane should be checked for TB yearly.
