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NURS 305 Final Exam: Questions, Answers, and Rationales

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This document is a NURS 305 final exam review that includes multiple-choice questions with answers and explanations. It covers key nursing topics like pharmacology, patient care, and clinical decision-making, making it a helpful study tool for exam preparation.

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NURS 305 Final Exam Questions And Answers With Complete
Solutions
NURS 305 Final Exam Questions And Answers With Complete Solutions


During therapy with hemtopoietic drugs, the nurse will monitor the patient for which adverse
effects? SATA
A. diarrhea
B. edema
C. nausea and vomiting
D. hypotension
E. headache
F. black tarry stools
Answer: A,B,C,E


A patient is to receive filgrastim (Neupogen) 5 mcg/kg/day. The patient weighs 198 lbs.
Calculate how many micrograms of medication this patient will receive each day.
A. 450 mcg
B. 4.5 mcg
C. 45 mcg
D. 4500 mcg
Answer: A


What is the general action of immunosuppressants?
A. they inhibit T-lymphocytes
B. they increase natural killer cellular activity
C. they increase antibody response
D. they re hepatic metabolism of steroids
Answer: A


The nurse should teach the client about which expected adverse effect of filgastrim (Neupogen)?
A. insomnia
B. constipation
C. bone pain
D. hypotension
Answer: C


NURS 305 Final Exam QuestionS 1

, NURS 305 Final Exam Questions And Answers With Complete
Solutions
Which client finding would the nurse hold the prescribed dose of filgastrim (Neupogen) for and
notify the health care provider about?
A. blood pressure of 142/88 mm Hg
B. absolute neutrophil count (ANC) 12,000
C. temperature of 99.5 F
D. WBC count of 4.5
Answer: B


A patient is prescribed monoclonal antibody therapy for the treatment of rheumatoid arthritis.
What patient condition should alter the nurse to question the prescription for this class of drug?
A. Nephrotic syndrome
B. acquired immune deficiency syndrome (AIDS)
C. Chronic obstructive pulmonary disease
D. hypertensive emergency
Answer: B


What are the functional cells of the humoral immune system that mature into immunoglobulins?
A. RBCs
B. anulocytes
C. B cells
D. T cells
Answer: C


What is the mechanism of action of biologic response modifying drugs? SATA
A. interuption of the cell lifecycle at the genetic level to interfere with growth of the cancer
cell
B. direct toxic effect on tumor cells, causing them to rupture
C. enhancement or restoration of the host's immune system defenses against a tumor
D. regulation of genes expression that occurs during transcription
E. adverse modification of a tumor's biology, making it harder for the tumor cells to survive
and reproduce
Answer: B, C, E




NURS 305 Final Exam QuestionS 2

, NURS 305 Final Exam Questions And Answers With Complete
Solutions
When monitoring a patient's response to interferon therapy, the nurse notes that the major dose-
limiting factors for interferon therapy is which condition?
A. nausea and vomiting
B. fatigue
C. diarrhea
D. anxiety
Answer: B


A patient asks about his cancer treatment with monoclonal antibodies. The nurse tell him that
which is the major advantage of treating certain cancers with monoclonal antibodies?
A. they are more effective against metastatic tumors
B. they will help the patient improve more quickly than will other antineoplastic drugs
C. there are fewer incidences of opportunistic infections with monoclonal antibodies
D. monoclonal antibodies target certain tumor cells and bypass normal cells
Answer: D


During a patient's therapy with interleukins, the nurse monitors the patient for capillary leak
syndrome. Which assessment finding, if present, would indicate this problem?
A. a dry cough
B. bruising on the skin
C. bradycardia
D. a sudden 15 pound weight gain
Answer: D


A patient who has received chemotherapy has a steadily decreasing white blood cell count. The
chemotherapy will end on Tuesday afternoon. The oncologist has mentioned that a colony-
stimulating factor will be started soon. The nurse knows that the appropriate time to start this
medication is when?
A. a.in 2 to 4 days, after the white blood cells have reached their nadir
B. b. two hours after the chemotherapy ends
C. c. while the patient is still receiving chemotherapy
D. d. Wednesday afternoon 24 hours after the chemotherapy ends
Answer: D



NURS 305 Final Exam QuestionS 3

, NURS 305 Final Exam Questions And Answers With Complete
Solutions
A patient has an order for the monoclonal antibody. The nurse notes that the patient does not
have a history of cancer. What is another possible reason for administering this drug?
A. thrombocytopenia
B. rheumatoid arthritis
C. severe anemia
D. osteoporosis
Answer: B


During interleukin drug therapy, a patient is showing signs of severe fluid retention, with
increasing dyspnea and severe peripheral edema. The next dose of the interleukin is due now.
Which action will the nurse take next?
A. give the drug and notify the prescriber
B. monitor the patient for 2 hours and then give the drug if the patient's condition improves
C. hold the drug and notify the prescriber
D. give the drug along with acetaminophan and diphendhydramine (Benadryl)
Answer: C


The nurse would anticipate administering which medication to a client demonstrating acute
organ rejection?
A. basiliximab (Simulect)
B. muromonab-CD3 (Orthoclone OKT3)
C. sirolimus (Rapamune)
D. azathioprine (Imuran)
Answer: B


The nurse would teach a client prescribed cyclosporine (Sandimmune) to avoid which substance?
A. acetominophen
B. grapefruit juice
C. sunscreen
D. chocolate milk
Answer: B


Before administration of an immunosuppressant drug, the nurse, should perform which actions?
SATA

NURS 305 Final Exam QuestionS 4

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