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1. pulmonary disorder seen in childhood, noted increase in production of a protein producing thick
mucus that blocks the airway, pancreatic ducts, sweat gland ducts and vas deferens - CORRECT
ANSWER-cystic fibrosis AKA fibrocystic disease of pancreas
,a severe respiratory disease that is characterized by rapid respiratory failure, increased pulmonary
resistance and surfactant deficiency - CORRECT ANSWER-respiratory distress syndrome (RDS)
- anti-inflammatory, antipyretic, and analgesic properties
- used for reducing pain, stiffness, swelling, redness, and fever associated with local inflammation
- pros: fewer side effects and longer duration of actions
-NSAIDs are associated with an increased risk of adverse cardio events like stroke, MI, and hypertension
- CORRECT ANSWER-NSAIDs
analgesic, antipyretic but does not reduce inflammation - CORRECT ANSWER-Acetaminophen
(Tylenol)
NSAID
safe for patient with heart disease - CORRECT ANSWER-Naproxen (Aleve)
Nsaids and corticosteriods to reduce inflammation
Allopurinol - Reduces uric acid. Doesn't relieve acute gout attacks. Increase fluid intake May cause
hypoglycemia.
Colchicine - Used for initial prevention and chronic attacks. Decreases WBCs response to urate crystals.
Avoid grapefruit juice.
Allopurinol and febuxostat work on pathophysiological cause of gout - CORRECT ANSWER-
Gout Medications
renal calculi - CORRECT ANSWER-Comorbid condition in patient with gout
1. reduces inflammation by inhibiting synthesis of leukocyte microtubules
2. reduces pain in acute attack
, 3. does not stop gout from becoming chronic gout arthritis
4. efficacy is affected by incidence of adverse effects - CORRECT ANSWER-Colchicine (Colcrys)
- Inhibits production of uric acid and only anti gout to inhibit xanthine oxidase
- Used to treat gout and/or kidney stones of that nature
- Watch for kidney toxicity
- Contraindicated with Warfarin & oral hypoglycemic (increases effects of meds) - CORRECT
ANSWER-Allupurinol
1. can initiate an acute gout attack
2. colchcine, NSAIDs or corticosteroids are used with ULT drugs to decrease the incidence of ULT induced
gout attacks - CORRECT ANSWER-Urate lowering therapy
1. gout
2. high serum urate levels with underlying renal dysfunction
3. urinary calculi
4. histor of tophaceous gout - CORRECT ANSWER-Allupurinol (Zyloprim) Treats
NSAIDs : indomethacin ibuprofen, naproxen and sulindac - CORRECT ANSWER-Acute gout
attacks preferred treatment
1. GI bleed ( dark stools and epigastric pain)
2. to reduce side effects switch to COX2 inhibitor or Celecoxib - CORRECT ANSWER-NSAID side
effects
chronic, progressive arthritis with stiffening and fusion of joints, primarily of the spine and sacroiliac
joints - CORRECT ANSWER-ankylosing spondylitis
1. caused by acetaminophen overdoses