NR 566 MIDTERM EXAM 2025 UPDATE|| ACCURATE AND
FREQUENTLY TESTED QUESTIONS AND 100% CORRECT
ANSWERS WITH RATIONALES|| LATEST AND COMPLETE UPDATE
WITH EXPERT VERIFIED SOLUTIONS|| SURE PASS
When is orlistat contraindicated? - CORRECT ANS >> in those with
malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking orlistat...especially
if the patient is on coumadin? - CORRECT ANS >> monitor coumadin as
vitamin k deficiency may occur and intensify effect of coumadin.
A patient with a bmi of 27 would be considered: - CORRECT ANS >> overweight
Lorcaserin adverse effects - CORRECT ANS >> headache, uri, back pain,
hypoglycemia (in dm), blood dyscrasias, cognitive impairment, psychiatric
disorders, priapism, pulmonary hypertension, and valvular heart disease
Lorcaserin moa - CORRECT ANS >> reduces waist circumference, fasting
glucose, insulin, total cholesterol, ldl, triglycerides
When is lorcaserin contraindicated? - CORRECT ANS >> crcl <30
-not approved in children
Lorcaserin drug interactions - CORRECT ANS >> maoi inhibitors, ssris, snris,
st. Johns wart, and triptans
-increased risk for serotonin syndrome
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Naltrexone and bupropion black box warning - CORRECT ANS >> increased
risk for suicidal ideation and suicide attempts in children, adolescents, and young
adults
Do not take naltrexone and bupropion within weeks of taking a .-
CORRECT ANS >> two
-maoi
Due to naltrexone and bupropion antagonist effects, it can reduce effects of what?
- CORRECT ANS >> opioids
Naltrexone and bupropion contraindications - CORRECT ANS >> htn, seizure
disorders, eating disorders, alcohol or drug withdrawal
Liraglutide moa - CORRECT ANS >> promotes weight loss by slowing gastric
emptying
-increases satiety
-not approved children.
When taking liraglutide, it is not unusual for baseline hr to increase bpm
- CORRECT ANS >> 10-20
-monitor for tachycardia
When taking liraglutide, monitor for in patients with diabetes -
CORRECT ANS >> hypoglycemia
Baseline labs for liraglutide - CORRECT ANS >> lipids, cmp, hga1c q 6 months,
triglycerides
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Liraglutide black box warning - CORRECT ANS >> associated with a risk for
thyroid c- cell tumors based on studies in rodents
-contraindicated in people with multiple endocrine neoplasia syndrome type 2
(men 2) or personal/family history of medullary thyroid carcinoma
Which non-amphetamines are fda approved for weight loss that have lower abuse risk?
- CORRECT ANS >> phentermine and diethylpropion
How does phentermine and diethylpropion promote weight loss? - CORRECT ANS
>>
Promote weight loss by decreasing appetite
-they are central nervous system (cns) stimulants that suppress appetite by
increasing the availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? -
CORRECT ANS >> 3 months or less
What drug schedule are phentermine and diethylpropion under? - CORRECT ANS
>>
Schedule iv
What labs should be monitored with phentermine and diethylpropion? What
condition should we screen for? - CORRECT ANS >> baseline cmp (watch
electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - CORRECT ANS >> increase hr and bp
-dry mouth and constipation
What is role of topiramate in weight loss? - CORRECT ANS >> increases satiety
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What are some phentermine/topiramate contraindications for use? - CORRECT ANS
>>
Not approved in children and contraindicated with severe hepatic impairment
How should we educate patient to take phentermine/topiramate to avoid insomnia?
- CORRECT ANS >> given before 1600
What are some high-risk patient conditions that we should use
phentermine/topiramate with caution? - CORRECT ANS >> hx drug abuse,
glaucoma, pregnant, htn, hyperthyroidism
Phentermine/topiramate adverse effects - CORRECT ANS >> insomnia,
nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. - CORRECT ANS >> a) glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin d deficiency
F) A, b, e
Answer: a,c,d
Orlistat is a lipase inhibitor that acts on the and reduces absorption of
fat by 30%. - CORRECT ANS >> gi tract