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SCHOLARVAULT
, Chapter 1: Principles of Pharmacology
Multiple Choice
1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action
2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action
4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action
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Page 1 #weof
#we
SCHOLARVAULT 247 #we
,5. The administration #weof #weoxytocin #wehas #webeen #weproposed #weas #wea #wetreatment #wefor
#weautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: #wec
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
6. Which #wefactor #wedoes #wenot #weaffect #wethe #wepharmacokinetics #weof #wea #wedrug?
a. Route #weof #weadministration
b. Lipid #wesolubility
c. Depot #webinding
d. Drug #weaction
Answer: #wed
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
7. First-pass #wemetabolism #weoccurs #wewhen #wedrugs #weare #wetaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: #wea
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
8. The #wearea #wepostrema #weis #weone #wearea #wein #wethe #webrain #wewhere #wethe is #wenot #wecomplete.
a. cerebrospinal #wefluid
b. blood–brain #webarrier
c. choroid #weplexus
d. phospholipid #wemembrane
Answer: #web
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
9. First-pass #wemetabolism #weoccurs #wewith #weorally #weadministered #wedrugs #webecause
a. their #weabsorption #weis #weslowed #weby #wefood.
b. drugs #weabsorbed #weinto #wethe #webloodstream #wefrom #wethe #westomach #wego #weto #wethe #weliver
#weon #wethe #weway #weto #wegeneral #wecirculation.
c. drugs #wemust #wefirst #wesurvive #wethe #weacidic #weenvironment #weof #wethe #westomach.
d. salivary #weenzymes #wein #wethe #wemouth #webegin #wethe #weprocess #weof #wemetabolism.
Answer: #web
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
10. Toxic #wesubstances #wein #wethe #weblood #wetrigger #wea #wevomiting #weresponse #weby #weactivating #wethe
a. blood–brain #webarrier.
b. choroid #weplexus.
c. area #wepostrema.
d. median #weeminence.
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Page 2 #weof
#we
SCHOLARVAULT 247 #we
, Answer: #wec
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
11. Drugs #weadministered #we_ have #wethe #wemost #werapid #weonset #weof #weaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: #wed
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
12. Ionization #weof #wea #wedrug #wedepends #weon #wethe of #wethe #wesolution #weand #wethe of
#wethe #wedrug.
a. pH; #wepKa
b. pKa; #wepH
c. concentration; #welipid #wesolubility
d. pH; #weconcentration
Answer: #wea
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
13. The #weabsorption #weof #wea #wedrug #wedepends #weon #weall #weof #wethe #wefollowing #weexcept
a. lipid #wesolubility.
b. ionization.
c. body #wetemperature.
d. the #weconcentration #weof #wethe #wedrug.
Answer: #wec
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
14. Drugs #wethat #weare should #webe #weavoided #weby #wewomen #weof #wechildbearing #weage.
a. teratogenic
b. able #weto #wecross #wethe #weplacental #webarrier
c. psychoactive
d. highly #welipid-soluble
Answer: #wea
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
15. Agents #wethat #weinduce #wedevelopmental #weabnormalities #wein #wea #wefetus #weare #weknown #weas
a. psychoactive #wedrugs.
b. illicit #wedrugs.
c. teratogens.
d. placental #wedrugs.
Answer: #wec
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
16. Depot #webinding #weis #wesaid #weto #weoccur #wewhen #wedrugs
a. bind #weto #wetheir #wetarget #wesites.
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Page 3 #weof
#we
SCHOLARVAULT 247 #we
#we
#we
SCHOLARVAULT
, Chapter 1: Principles of Pharmacology
Multiple Choice
1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action
2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action
4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action
WWW.THENURSINGMASTERY.COM
Page 1 #weof
#we
SCHOLARVAULT 247 #we
,5. The administration #weof #weoxytocin #wehas #webeen #weproposed #weas #wea #wetreatment #wefor
#weautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: #wec
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
6. Which #wefactor #wedoes #wenot #weaffect #wethe #wepharmacokinetics #weof #wea #wedrug?
a. Route #weof #weadministration
b. Lipid #wesolubility
c. Depot #webinding
d. Drug #weaction
Answer: #wed
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
7. First-pass #wemetabolism #weoccurs #wewhen #wedrugs #weare #wetaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: #wea
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
8. The #wearea #wepostrema #weis #weone #wearea #wein #wethe #webrain #wewhere #wethe is #wenot #wecomplete.
a. cerebrospinal #wefluid
b. blood–brain #webarrier
c. choroid #weplexus
d. phospholipid #wemembrane
Answer: #web
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
9. First-pass #wemetabolism #weoccurs #wewith #weorally #weadministered #wedrugs #webecause
a. their #weabsorption #weis #weslowed #weby #wefood.
b. drugs #weabsorbed #weinto #wethe #webloodstream #wefrom #wethe #westomach #wego #weto #wethe #weliver
#weon #wethe #weway #weto #wegeneral #wecirculation.
c. drugs #wemust #wefirst #wesurvive #wethe #weacidic #weenvironment #weof #wethe #westomach.
d. salivary #weenzymes #wein #wethe #wemouth #webegin #wethe #weprocess #weof #wemetabolism.
Answer: #web
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
10. Toxic #wesubstances #wein #wethe #weblood #wetrigger #wea #wevomiting #weresponse #weby #weactivating #wethe
a. blood–brain #webarrier.
b. choroid #weplexus.
c. area #wepostrema.
d. median #weeminence.
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Page 2 #weof
#we
SCHOLARVAULT 247 #we
, Answer: #wec
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
11. Drugs #weadministered #we_ have #wethe #wemost #werapid #weonset #weof #weaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: #wed
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
12. Ionization #weof #wea #wedrug #wedepends #weon #wethe of #wethe #wesolution #weand #wethe of
#wethe #wedrug.
a. pH; #wepKa
b. pKa; #wepH
c. concentration; #welipid #wesolubility
d. pH; #weconcentration
Answer: #wea
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
13. The #weabsorption #weof #wea #wedrug #wedepends #weon #weall #weof #wethe #wefollowing #weexcept
a. lipid #wesolubility.
b. ionization.
c. body #wetemperature.
d. the #weconcentration #weof #wethe #wedrug.
Answer: #wec
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
14. Drugs #wethat #weare should #webe #weavoided #weby #wewomen #weof #wechildbearing #weage.
a. teratogenic
b. able #weto #wecross #wethe #weplacental #webarrier
c. psychoactive
d. highly #welipid-soluble
Answer: #wea
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
15. Agents #wethat #weinduce #wedevelopmental #weabnormalities #wein #wea #wefetus #weare #weknown #weas
a. psychoactive #wedrugs.
b. illicit #wedrugs.
c. teratogens.
d. placental #wedrugs.
Answer: #wec
Textbook #weReference: #wePharmacokinetic #weFactors #weDetermining #weDrug #weAction
16. Depot #webinding #weis #wesaid #weto #weoccur #wewhen #wedrugs
a. bind #weto #wetheir #wetarget #wesites.
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Page 3 #weof
#we
SCHOLARVAULT 247 #we