ACTUAL Exam Questions and CORRECT
Answers
Is parthenogenesis an option in mammals? - CORRECT ANSWER - To date, no
What is sex determination? - CORRECT ANSWER - - male or female
- appropriate gonad is formed accordingly
What is sexual differentiation? - CORRECT ANSWER - - sexual phenotype
- hormone-induced differentiation on non-gonadal tissue (e.g. the ducts, etc)
Chromosome size and number are not indicative of... - CORRECT ANSWER - the
genome size (e.g. Indian muntjac 2n = 6)
Most aneuploidies are... - CORRECT ANSWER - embryonic lethals
The aneuplodies that are tolerated typically consist of - CORRECT ANSWER - trisomies
of small chromosomes
Normal male phenotype - CORRECT ANSWER - XY & XYY
Normal female phenotype - CORRECT ANSWER - XX & XXX (Trisomy X)
Anything with no x chromosome is a... - CORRECT ANSWER - embryonic lethal
Turner's syndrome - CORRECT ANSWER - XO (monosomy X)
, Klinefeller Syndrome - CORRECT ANSWER - XXY (phenotypically male)
Non-disjunction on the paternal side during MII results in a child with what kind of syndrome? -
CORRECT ANSWER - Kline feller Syndrome (XXY)
Disjunction in MI or MII on the parternal side results in Kline feller Syndrome (XXY)? -
CORRECT ANSWER - MII
What is the only gene on the Y chromosome required for testes determination and the generation
of a male? - CORRECT ANSWER - Sex-determining Region on Y (SrY)
Another name for Sry is... - CORRECT ANSWER - Testes-determining factor (TDF)
Sry is a member of which family of transcription factors? - CORRECT ANSWER - SOX
(Sry-related HMG box) family
What is common among members of the SOX (Sry-related HMG box) family? - CORRECT
ANSWER - They all contain a conserved high mobility group (HMG) box
SRY transcription factor is only found in what kinds of animals? - CORRECT ANSWER -
Mammals (eutherians, marsupials, but not monotremes)
Sry is expressed very transiently by - CORRECT ANSWER - The pre-Sertoli cells (cells
in the gential ridge that are derived from the coelomic epithelium cells)
SRY promotes the pre-Sertoli cells to form - CORRECT ANSWER - testes cords
Which transcription factor binds to many of the same targets as Sry? - CORRECT
ANSWER - SOX9