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Radiation Therapy Exam (Questions & Answers) Rated 100% Correct!!

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Radiation Therapy Exam (Questions & Answers) Rated 100% Correct!! Fractionation Schedules - Answer- Standard Hyper fractionation Hypo fractionation Accelerated Fractionation Standard fractionation - Answer- daily single doses typically between 1.8-2.0 Gy per day, delivered 5 days per week Hyper fractionation - Answer- - smaller than standard doses - Given more than once daily (separated by at least 6 hours) - done over the standard treatment time - allows increased dose delivery - reduces late complication Hypo fractionation - Answer- - use of larger daily doses, which - less total dose over a shorter treatment time - allows treatment over a shorter period of time; - increased risk of late toxicity Accelerated fractionation - Answer- Standard doses are given more than once daily over a shortened treatment time (minimizes tumor cell repopulation) Radio sensitizing chemotherapeutic agents include: - Answer- - Mitomycin - Cisplatin - Vinorelbine - Paclitaxel - Docetaxel - 5FU Radio protectors such as amifostine and dexrazoxane. - Answer- protect cells that are well oxygenated, such as normal cells, but do not have much effect on hypoxic cells, such as tumor cells Low dose radiation (LDR) - Answer- continuous treatment administered over several hours or days in a protected lead shielded room High dose radiation (HDR) - Answer- source used rapidly deposits energy and treatment may be given over a few minutes in either one or several doses (at least six hours apart) Standard Dose Range for radical radiation of solid tumors - Answer- 60-80 Gy (over 30-40 fractions) Standard Dose Ranges for adjuvant radiation of solid tumors - Answer- 45-46 Gy (over 25-30 fractions) Standard Dose Ranges for radical radiation of lymphomas - Answer- 20-50 Gy (over 10-25 fractions) Standard Dose Ranges for palliative radiation - Answer- 4-30 Gy (over 1-15 fractions) Gross tumor volume versus clinical tumor volume - Answer- - gross = extrent of malignant growth as outline by imaging - clinical = gross + margin to accomodate for subclinical (miroscopic) disease Intensity modulated radiation therapy (IMRT) - Answer- allows for different parts of the area to be treated to receive different doses.

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Radiation Therapy Exam (Questions &
Answers) Rated 100% Correct!!
Fractionation Schedules - Answer- Standard
Hyper fractionation
Hypo fractionation
Accelerated Fractionation

Standard fractionation - Answer- daily single doses typically between 1.8-2.0 Gy per
day, delivered 5 days per week

Hyper fractionation - Answer- - smaller than standard doses
- Given more than once daily (separated by at least 6 hours)
- done over the standard treatment time
- allows increased dose delivery
- reduces late complication

Hypo fractionation - Answer- - use of larger daily doses, which
- less total dose over a shorter treatment time
- allows treatment over a shorter period of time;
- increased risk of late toxicity

Accelerated fractionation - Answer- Standard doses are given more than once daily
over a shortened treatment time (minimizes tumor cell repopulation)

Radio sensitizing chemotherapeutic agents include: - Answer- - Mitomycin
- Cisplatin
- Vinorelbine
- Paclitaxel
- Docetaxel
- 5FU

Radio protectors such as amifostine and dexrazoxane. - Answer- protect cells that are
well oxygenated, such as normal cells, but do not have much effect on hypoxic cells,
such as tumor cells

Low dose radiation (LDR) - Answer- continuous treatment administered over several
hours or days in a protected lead shielded room

High dose radiation (HDR) - Answer- source used rapidly deposits energy and
treatment may be given over a few minutes in either one or several doses (at least six
hours apart)

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