Exam With Correct
Questions and Answers
2025/2026
Hypersensitivity: Type 1 - Correct Answers--Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2 - Correct Answers--Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
Hypersensitivity 2 - Correct Answers--Graves Disease (hyperthyroidism) -
alters function not destroy
-blood transfusions reaction- transfused erythrocytes are destroyed by
agglutination or lysis
-drug allergies
-hemolytic anemia
Hypersensitivity: type 3 - Correct Answers--Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was
released into the blood or bodily fluids, and the complex is then deposited in
the tissues
Hypersensitivity: Type 3 - Correct Answers--rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
Hives (urticaria) - Correct Answers-Hypersensitivity Type 1
First responders to innate the immune system - Correct Answers-Neutrophils
Allergic contact dermatitis - Correct Answers-Hypersensitivity Type IV
Type 2 cytotoxic hypersensitivity mediated by: - Correct Answers--IgG IgM
-macrophages are primary effort cells
, -
Serum Sickness - Correct Answers-type 3 hypersensitivity
Hypersensitivity IV, - Correct Answers--is more of a delayed immune
response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune - Correct Answers--diseases in which the body makes
antibodies directed against its own tissues
-
Primary immunodeficiency - Correct Answers--Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
secondary immunodeficiency - Correct Answers--acquired
Common cause of secondary immunodeficiency - Correct Answers-
Malnutrition
Most patients diagnosed with SLE will have a positive ? - Correct Answers-
antinuclear antibody (ANA)
SLE (lupus) - Correct Answers--Facial rash
-vasculitis
- tissue inflammation
Renal disease associated with autoimmunity? - Correct Answers-
Glomerulonephritis
Sjogren's syndrome - Correct Answers-Inflammation in salivary and lacrimal
glands
SLE - Correct Answers-Autoantibodies and auto-active t-cells against DNA
and nucleoprotein
Sjögren's syndrome immune changes: - Correct Answers-Autoantibodies and
auto-reactive t-cells against apoptotic cells
rheumatoid arthritis manifestations: - Correct Answers-Joint inflammation,
stiffness, pain, loss of range of motion
Rheumatoid Arthritis immune changes: - Correct Answers-T-cells and B cells
against joint associated antigens