Page | 1
NU 545 ch 7 Questions with Detailed
Verified Answers
Question: Cathelicidins
Ans: Family of antimicrobial peptides that in humans has one member.
Question:Defensins
Ans: antimicrobial peptides that inhibit microbial growth
Question:Mannose-binding lectin (MBL)
Ans: soluble acute-phase protein in the blood that binds to mannose
residues on pathogen surfaces and, when bound, activates the
complement system by the lectin pathway
Question:Resistin-like molecule beta
Ans: Found in intestinal goblet cells, where it appears to protect against
helminth infections.
Question:Antimicrobial lectins
Ans: Lectin (carbohydrate binding protein) family with activity against
Gram+ bacteria; C-type lectins
, Page | 2
Question:Bactericidal/permeability-inducing protein (BPI)
Ans: Stored in neutrophils and intestinal epithelium. Reacts with
lipopolysaccharide on the surface of gram-negative bacteria, resulting in
bacterial lysis.
Question:inflammatory response
Ans: nonspecific defense reaction to tissue damage caused by injury or
infection
Question:acute inflammatory response
Ans: series of cellular changes that bring blood to the site of an injury or
infection.
1)vasodilation
2)increased vascular permeability
3)diapedesis
Question:Diapedesis
Ans: Passage of white blood cells through intact vessel walls into tissue
Question:3 plasma protein systems
, Page | 3
Ans: complement, clotting, kinin
Question:proenzyme
Ans: an inactive precursor of an enzyme
Question:complement system
Ans: A group of about 30 blood proteins that may amplify the
inflammatory response, enhance phagocytosis, or directly lyse
extracellular pathogens.
Question:3 pathways of complement system
Ans: classical, alternative, lectin
Question:classical pathway
Ans: activated by antibodies bound to antigen, which interact with
complement system. Begins with activation of complement protein C1
Question:lectin pathway
Ans: mannose-binding lectin binds to pathogen surface. It is antibody
independent.
Question:Anaphylaxotoxins
NU 545 ch 7 Questions with Detailed
Verified Answers
Question: Cathelicidins
Ans: Family of antimicrobial peptides that in humans has one member.
Question:Defensins
Ans: antimicrobial peptides that inhibit microbial growth
Question:Mannose-binding lectin (MBL)
Ans: soluble acute-phase protein in the blood that binds to mannose
residues on pathogen surfaces and, when bound, activates the
complement system by the lectin pathway
Question:Resistin-like molecule beta
Ans: Found in intestinal goblet cells, where it appears to protect against
helminth infections.
Question:Antimicrobial lectins
Ans: Lectin (carbohydrate binding protein) family with activity against
Gram+ bacteria; C-type lectins
, Page | 2
Question:Bactericidal/permeability-inducing protein (BPI)
Ans: Stored in neutrophils and intestinal epithelium. Reacts with
lipopolysaccharide on the surface of gram-negative bacteria, resulting in
bacterial lysis.
Question:inflammatory response
Ans: nonspecific defense reaction to tissue damage caused by injury or
infection
Question:acute inflammatory response
Ans: series of cellular changes that bring blood to the site of an injury or
infection.
1)vasodilation
2)increased vascular permeability
3)diapedesis
Question:Diapedesis
Ans: Passage of white blood cells through intact vessel walls into tissue
Question:3 plasma protein systems
, Page | 3
Ans: complement, clotting, kinin
Question:proenzyme
Ans: an inactive precursor of an enzyme
Question:complement system
Ans: A group of about 30 blood proteins that may amplify the
inflammatory response, enhance phagocytosis, or directly lyse
extracellular pathogens.
Question:3 pathways of complement system
Ans: classical, alternative, lectin
Question:classical pathway
Ans: activated by antibodies bound to antigen, which interact with
complement system. Begins with activation of complement protein C1
Question:lectin pathway
Ans: mannose-binding lectin binds to pathogen surface. It is antibody
independent.
Question:Anaphylaxotoxins
