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CHEM 219 Module 56– Principles of Organic Chemistry Study Guide | 2025 | Portage Learning

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This document is a comprehensive study guide for CHEM 219 Module 6: Principles of Organic Chemistry, updated for 2025 and aligned with Portage Learning standards. It includes practice-style questions, concept explanations, and worked examples to reinforce understanding of advanced organic chemistry topics such as reaction mechanisms, functional groups, molecular structure, stereochemistry, and common organic reactions.

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CHEM 219 Module 6 Exams: Principles of
Organic Chemistry (2025) | Portage Learning
– Verified Q&A



1. Nucleophilic Acyl Substitution ANS Amines function as nitrogen

nucleophiles and the amine is acylated to create an amide

2. Nitrile functional group ANS C triple bond N

3. 2,4-diaminobenzoic acid ANS Name this molecule

4. Solubility decreases ANS As the size of the alkyl groups attached to the

nitrile group increases, what happens to the solubility?

5. Pyridine or non-nucleophilic bases ANS What is used to neutralize the acid

byproduct of nucleophilic acyl substitution?

6. Primary amines ANS What do nitriles reduce to?

7. Carboxylic acid and ammonium ion ANS Nitrile + water + acid =

8. 4-amino-2-butanone ANS Name this molecule

, 2


9. Can produce all degrees of amines ANS What is the advantage of alkylation

of amines?

10. Alkyl: 3-4, aromatic: 9 (resonance sharing in aromatic) ANS pKb of alkyl

amines vs aromatic amines

11. Carboxylic acids ANS What are amides derivatives of?

12. 1st, 2nd, and 3rd degree amines ANS What type of amines can be

produced by reducing amides?

13. Relatively high boiling points ANS Do nitriles have high or low boiling

points?

14. Sn2 reaction of cyanide ion with an unhindered primary or secondary

alkyl halide ANS What is the most common preparation of nitriles?

15. 1,4-diaminobutane ANS Name this molecule

16. Amides ANS Nucleophilic acyl substitution turns ammonia and amines

into?

17. Secondary amine (R2NH) ANS What does a primary amine alkylate to?

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