CHEM 219 Module 4 Exams: Principles of
Organic Chemistry (2025) | Portage Learning
– Verified Q&A
1. Substrate ANS Molecule on which substitution occurs
2. SN2 nucleophiles ANS Large, negative, low electronegativity, non-bulky
3. Cyanide ANS Nitrile
4. SN1 solvent ANS Polar protic
5. When is elimination possible ANS When there is at least one hydrogen
attached to the carbon attached to C-X
6. Elimination logistics ANS Removes hydrogen and halogen and creates an
alkene
7. E1 ANS 1. Carbocation forms (slow) 2. Nucleophile attacks hydrogen (fast)
8. Number of alkene products depends on ANS The beta sites
9. SN2 ANS Concerted, backside attack, inversion of tetrahedral, bimolecular
1
, 10. Functional group interconversion ANS Substitution, an alkyl halide is
converted into another functional group
11. Secondary alkyl halide mechanisms ANS All 4 can be mixture
12. Tertiary alkyl halide weak/acidic ANS SN1 and E1 mix
13. Ammonia ANS Amine
14. SN1 kinetics ANS Unimolecular, only substrate can speed up
15. Secondary alkyl halide weak bases ANS SN2
16. Nucleophile in elimination ANS Acts as a base and removes hydrogen
from beta carbon
17. Amide ANS Amine
18. Carboxylate ANS Ester
19. Which molecules cannot use substitution ANS Aryl and vinyl due to
non-sp3 hybridization
20. Water ANS Alcohol
21. Secondary alkyl halide strong bases ANS E2
2
Organic Chemistry (2025) | Portage Learning
– Verified Q&A
1. Substrate ANS Molecule on which substitution occurs
2. SN2 nucleophiles ANS Large, negative, low electronegativity, non-bulky
3. Cyanide ANS Nitrile
4. SN1 solvent ANS Polar protic
5. When is elimination possible ANS When there is at least one hydrogen
attached to the carbon attached to C-X
6. Elimination logistics ANS Removes hydrogen and halogen and creates an
alkene
7. E1 ANS 1. Carbocation forms (slow) 2. Nucleophile attacks hydrogen (fast)
8. Number of alkene products depends on ANS The beta sites
9. SN2 ANS Concerted, backside attack, inversion of tetrahedral, bimolecular
1
, 10. Functional group interconversion ANS Substitution, an alkyl halide is
converted into another functional group
11. Secondary alkyl halide mechanisms ANS All 4 can be mixture
12. Tertiary alkyl halide weak/acidic ANS SN1 and E1 mix
13. Ammonia ANS Amine
14. SN1 kinetics ANS Unimolecular, only substrate can speed up
15. Secondary alkyl halide weak bases ANS SN2
16. Nucleophile in elimination ANS Acts as a base and removes hydrogen
from beta carbon
17. Amide ANS Amine
18. Carboxylate ANS Ester
19. Which molecules cannot use substitution ANS Aryl and vinyl due to
non-sp3 hybridization
20. Water ANS Alcohol
21. Secondary alkyl halide strong bases ANS E2
2
