Regis: NU643 Module 4 questions with
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answers
Positive Symptoms of Psychosis - CORRECT ANSWERS
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✔✔"dramatic symptoms" such as delusions, and hallucinations
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Negative Symptoms of Psychosis - CORRECT ANSWERS
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✔✔Symptoms that mark the absence of features that would |\ |\ |\ |\ |\ |\ |\ |\ |\
normally be present, include alogia and avolition
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Stress diathesis Model of schizophrenia - CORRECT ANSWERS
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✔✔Genetic biases combined with environmental stressors lead to
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the development of schizophrenia
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D2 Receptor - CORRECT ANSWERS ✔✔Dopamine receptor most
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commonly targeted by antipsychotic medications.
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Mesolimbic dopamine pathway - CORRECT ANSWERS
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✔✔Originates is the ventral tegmental area of the brainstem and
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terminates in the nuclease accumbens of the ventral striatum.
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Mesolimbic dopamine pathway - CORRECT ANSWERS
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✔✔Important for motivation, pleasure and reward, as well as
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implicated in positive symptoms of psychosis.
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, Mesocortical dopamine pathway - CORRECT ANSWERS|\ |\ |\ |\ |\ |\
✔✔Hypoactivity of this pathway is thought to be associated with
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negative and cognitive symptoms of schizophrenia
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Nigrostriatal dopamine pathway - CORRECT ANSWERS ✔✔Plays a
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key role in regulating movements
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Tuberoinfundibular dopamine pathway - CORRECT ANSWERS |\ |\ |\ |\ |\ |\
✔✔Regulates prolactin secretion. |\ |\
Glutamate - CORRECT ANSWERS ✔✔The major excitatory
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neurotransmitter in the central nervous system. |\ |\ |\ |\ |\
The NMDA receptor hypofunction hypothesis of schizophrenia. -
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CORRECT ANSWERS ✔✔Neurodevelopmental abnormalities in the
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formation of glutamate synapses
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Long term potentiation (LTP) - CORRECT ANSWERS
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✔✔"strengthening" of a synapse through structural and functional |\ |\ |\ |\ |\ |\ |\
changes, making neurotransmission more efficient
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D2 Receptor Antagonism - CORRECT ANSWERS ✔✔The primary
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mechanism of action of conventional antipsychotics
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Clozapine, Olanzapine - CORRECT ANSWERS ✔✔Atypical
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antipsychotics with the highest metabolic risk |\ |\ |\ |\ |\
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answers
Positive Symptoms of Psychosis - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\
✔✔"dramatic symptoms" such as delusions, and hallucinations
|\ |\ |\ |\ |\ |\
Negative Symptoms of Psychosis - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\
✔✔Symptoms that mark the absence of features that would |\ |\ |\ |\ |\ |\ |\ |\ |\
normally be present, include alogia and avolition
|\ |\ |\ |\ |\ |\
Stress diathesis Model of schizophrenia - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\
✔✔Genetic biases combined with environmental stressors lead to
|\ |\ |\ |\ |\ |\ |\
the development of schizophrenia
|\ |\ |\ |\
D2 Receptor - CORRECT ANSWERS ✔✔Dopamine receptor most
|\ |\ |\ |\ |\ |\ |\ |\
commonly targeted by antipsychotic medications.
|\ |\ |\ |\
Mesolimbic dopamine pathway - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\
✔✔Originates is the ventral tegmental area of the brainstem and
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
terminates in the nuclease accumbens of the ventral striatum.
|\ |\ |\ |\ |\ |\ |\ |\
Mesolimbic dopamine pathway - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\
✔✔Important for motivation, pleasure and reward, as well as
|\ |\ |\ |\ |\ |\ |\ |\ |\
implicated in positive symptoms of psychosis.
|\ |\ |\ |\ |\
, Mesocortical dopamine pathway - CORRECT ANSWERS|\ |\ |\ |\ |\ |\
✔✔Hypoactivity of this pathway is thought to be associated with
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
negative and cognitive symptoms of schizophrenia
|\ |\ |\ |\ |\
Nigrostriatal dopamine pathway - CORRECT ANSWERS ✔✔Plays a
|\ |\ |\ |\ |\ |\ |\ |\
key role in regulating movements
|\ |\ |\ |\
Tuberoinfundibular dopamine pathway - CORRECT ANSWERS |\ |\ |\ |\ |\ |\
✔✔Regulates prolactin secretion. |\ |\
Glutamate - CORRECT ANSWERS ✔✔The major excitatory
|\ |\ |\ |\ |\ |\ |\
neurotransmitter in the central nervous system. |\ |\ |\ |\ |\
The NMDA receptor hypofunction hypothesis of schizophrenia. -
|\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔Neurodevelopmental abnormalities in the
|\ |\ |\ |\ |\
formation of glutamate synapses
|\ |\ |\ |\
Long term potentiation (LTP) - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\
✔✔"strengthening" of a synapse through structural and functional |\ |\ |\ |\ |\ |\ |\
changes, making neurotransmission more efficient
|\ |\ |\ |\ |\
D2 Receptor Antagonism - CORRECT ANSWERS ✔✔The primary
|\ |\ |\ |\ |\ |\ |\ |\
mechanism of action of conventional antipsychotics
|\ |\ |\ |\ |\
Clozapine, Olanzapine - CORRECT ANSWERS ✔✔Atypical
|\ |\ |\ |\ |\ |\
antipsychotics with the highest metabolic risk |\ |\ |\ |\ |\
