Carbamazepine (Tegretol) can sometimes show subtherapeutic range due
to what? - ANSWER Carbamazepine auto-induces metabolism, leading to
lower levels despite good compliance
What are the black box warnings for Carbamazepine? - ANSWER
Dermatologic reactions
1. Steven's Johnson
2. Toxic epidermal necrolysis
What lab test should be ordered for patients on Carbamazepine? -
ANSWER CBC every 3-4 months because it can cause decreased WBC,
decreased platelets, and trouble with RBC
What kind of teaching needs to be done with families of patients who
have seizure disorders? - ANSWER Prevention is important, patient
safety is important, Do NOT abruptly stop taking medication.
Ethosuximide (Zarontin), an anti-seizure medication can cause what? -
ANSWER Blood dyscrasias
, Patients taking Topiramate need to be monitored for what electrolyte
imbalance? - ANSWER Decreased sodium bicarb leading to
hyperchloremic metabolic acidosis
Topiramate treats seizures and what is one common side effect? -
ANSWER Normal side effect is weight loss, especially in higher dose
patients
A child on Topiramate that wants to play sports should monitor what? -
ANSWER Don't get overheated. Topiramate may affect his ability to
sweat in the heat.
What should a pregnant patient be told about taking Valproate
(Depakote)? - ANSWER It is a known teratogen and category X
medication. It should not be used in the first trimester, it may be
restarted in second trimester.
What patient population should tricyclic antidepressants be used
cautiously in? - ANSWER Heart Disease patients
Phenelzine (Nardil) is a MAOI. What teaching needs to be done with this
medication? - ANSWER He should not use serotonergic drugs like
Imitrex. Also, this class of medication interacts with yogurt, sour cream,
soy sauce, etc.
Phenelzine (Nardil) may cause what if there is an interaction with known
contraindicated foods? - ANSWER Hypertensive crisis
to what? - ANSWER Carbamazepine auto-induces metabolism, leading to
lower levels despite good compliance
What are the black box warnings for Carbamazepine? - ANSWER
Dermatologic reactions
1. Steven's Johnson
2. Toxic epidermal necrolysis
What lab test should be ordered for patients on Carbamazepine? -
ANSWER CBC every 3-4 months because it can cause decreased WBC,
decreased platelets, and trouble with RBC
What kind of teaching needs to be done with families of patients who
have seizure disorders? - ANSWER Prevention is important, patient
safety is important, Do NOT abruptly stop taking medication.
Ethosuximide (Zarontin), an anti-seizure medication can cause what? -
ANSWER Blood dyscrasias
, Patients taking Topiramate need to be monitored for what electrolyte
imbalance? - ANSWER Decreased sodium bicarb leading to
hyperchloremic metabolic acidosis
Topiramate treats seizures and what is one common side effect? -
ANSWER Normal side effect is weight loss, especially in higher dose
patients
A child on Topiramate that wants to play sports should monitor what? -
ANSWER Don't get overheated. Topiramate may affect his ability to
sweat in the heat.
What should a pregnant patient be told about taking Valproate
(Depakote)? - ANSWER It is a known teratogen and category X
medication. It should not be used in the first trimester, it may be
restarted in second trimester.
What patient population should tricyclic antidepressants be used
cautiously in? - ANSWER Heart Disease patients
Phenelzine (Nardil) is a MAOI. What teaching needs to be done with this
medication? - ANSWER He should not use serotonergic drugs like
Imitrex. Also, this class of medication interacts with yogurt, sour cream,
soy sauce, etc.
Phenelzine (Nardil) may cause what if there is an interaction with known
contraindicated foods? - ANSWER Hypertensive crisis
