NR 511 Final Anemia & Men's Health

NRnj511njFinalnjAnemianj&njMen'snjHea
lth
1.MeannjCorpuscularnjVolume
1. MCVnjindicatesnjthenjaveragenjsizenjofnjindividualnjrednjbloodnjcellsnj(RBCs).njT
henjnormalnj(normocytic)njrange:nj1.njisnj76njtonj96njfL.
2.Macrocyticnjvsnjmicrocyticnjvsnjnormocyticnjanemianj(causes,njsymptoms,njte
st-njing)
1. Mico-njsmallnjsizenjofnjRBCs,
2. Micronjcauses
3. Macro-
4. Macronjcauses
5. Normocytic
6. Normocyticnjcauses-:nj1.njMCVnjvaluenjofnjlessnjthannj80njfL.
2.nutritionalnjdeficiency=iron.njanemianjofnjchronicnjdisease,njthalassemias,njs
ideroblastic.njLeadnjpoisoning-(microcytic/hypochromic),njRA
3.MCVnj>100njfL
4.vitaminnjb12,njfolicnjacid,njmedication-
inducednj(allopurinol,njASA,njantacids,njPPIs,njAbx:njtetracycline,njerythromyci
n,njzidovudine),njperniciousnjanemia,njhypothyroidism,njlivernjdisease/ETOH,
5.MCVnj80-100njfL
6.sepsis,njhemorrhage,njhemolysis,njdrug-
induced,njaplastic,njradiation,njornjhereditarynjspherocytosis.
3.Julianjasksnjhownjsmokingnjincreasesnjthenjrisknjofnjfolicnjacidnjdeficiency.njY
ounjrespondnjthatnjsmoking:
1. Causesnjsmallnjvesselnjdiseasenjandnjconstrictsnjallnjvesselsnjthatnjtransp
ortnjessentialnjnutrients.
2. DecreasesnjvitaminnjCnjabsorption.
3. Affectsnjthenjliver'snjabilitynjtonjstorenjfolicnjacid.
4. Causesnjnausea,njtherebynjinhibitingnjthenjappetitenjandnjingestionnjofnjfoodsnjri
chnjinnjfolicnjacid:nj2.njDecreasesnjvitaminnjCnjabsorption.
4.Macrocyticnjnormochromicnjanemiasnjarenjcausednjby:
1. Acutenjbloodnjloss.
2. Annjinfectionnjornjtumor.
3. Anjnutritionalnjdeficiencynjofnjiron.
4. Anjdeficiencynjofnjfolicnjacid:nj4.njAnjdeficiencynjofnjfolicnjacid
5.Risks,njdiagnosisnjandnjtreatmentnjofnjhematologicalnjdisorders:


6.ListnjtypesnjofnjanemianjassociatednjwithnjMicrocyticnj(MCV<80njfL):njIronnjdefici
encynjAnemia
Sideroblastic
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lth
Thalassemia
Anemianjofnjchronicnjdisease

7.IdentifynjifnjeachnjitemnjbelownjisnjHypochromic,njNormochromic,njornjHyp
er-njchromic:
Ironnjdeficiency
AnemianjofnjinflammationnjandnjchronicnjdiseasenjSid
eroblastic
HereditarynjspherocytosisnjThalassemi
a:njMicrocyticnjHypochromicnjIronnjdefi
ciency
SideroblasticnjT
halassemia
MicrocyticnjNormochromic
AnemianjofnjinflammationnjandnjchronicnjdiseasenjM
icrocyticnjHyperchromic
Hereditarynjspherocytosis
8.Anj28-year-
oldnjfemalenjpresentsnjtonjyournjprimarynjcarenjofficenjfornjannjannualnjphysical.njSh
enjdeniesnjanynjcomplaintsnjothernjthannjheavynjmenstrualnjbleeding,njwhichnjisnjs
omethingnjshenjhasnjexperiencednjhernjwholenjlife.njOnnjroutinenjcompletenjbloodnj
countnj(CBC)njevaluation,njhernjhemoglobinnjisnj11.0.njOthernjpertinentnjvaluesnjincl
udenjanjdecreasednjserumnjferritinnjandnjelevatednjtotalnjiron-
bindingnjcapacitynj(TIBC).njHernjmeannjcorpuscularnjvolumenj(MCV)njisnj75.njWhich
njofnjthenjfollowingnjisnjthenjlikelynjcausenjofnjhernjanemia?

1. Ironnjdeficiencynjanemia.
2. Thalassemia.
3. Sideroblasticnjanemia.
4. Anemianjofnjchronicnjdiseasenj(ACD).:nj1.njIronnjdeficiencynjanemia.
9.52.njYournjclientnjShirleynjhasnjannjelevatednjmeannjcorpuscularnjvolumenj(MC
V).njWhatnjshouldnjyounjbenjconsideringnjinnjtermsnjofnjdiagnosis?
1. Ironnjdeficiencynjanemias.
2. Hemolyticnjanemias.
3. Leadnjpoisoning.
4. Livernjdisease:nj4.njLivernjdisease
10.Sherri'snjbloodnjworknjreturnsnjwithnjanjdecreasednjmeannjcorpuscularnjvolum
enj(MCV)njandnjanjdecreasednjmeannjcorpuscularnjhemoglobinnjconcentrationnj(MC
HC).njWhatnjshouldnjyounjdonjnext?
1. Ordernjanjserumnjironnjlevelnjandnjanjtotalnjiron-bindingnjcapacitynj(TIBC)njlevel.
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2. Ordernjanjserumnjferritinnjlevel.




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3. Ordernjanjserumnjfolatenjlevel.
4. Ordernjanjserumnjironnjlevel,njanjtotalnjiron-
bindingnjcapacitynj(TIBC)njlevel,njandnjanjserumnjferritinnjlevel.:nj4.njOrdernjanjserum
njironnjlevel,njanjtotalnjiron-

bindingnjcapacitynj(TIBC)njlevel,njandnjanjserumnjferritinnjlevel.
11.Reticulocytenjcount
1. Thenjreticulocytenjcountnjindicatesnjthenjpercentagenjof
2. Thenjreticulocytenjcountnjisnjelevatednjinnjcasesnjof
3. itnjmightnjalsonjbenjelevatednjduringnjtreatmentnjofnjanemiasnj(eg,:nj1.njnewlynjmat
uringnjRBCsnjreleasednjintonjthenjcirculatingnjbloodnjfromnjthenjbonenjmarrow.
2.bloodnjlossnjasnjthenjbodynjtriesnjtonjreplacenjthenjloss;
3.iron,njfolicnjacid,njandnjvitaminnjB12njandnjbonenjmarrownjdisorders,njwhennjim
maturenjRBCsnjarenjdisplacednjbynjothernjproliferatingnjcells
12.X-
linkednjdisordersnjinnjAfricannjAmericannjmales:njGDPnjDeficiency;njItnjisnjannjen
zymenjdefectnjthatnjcausesnjepisodicnjhemolyticnjanemianjbecausenjofnjthenjd
ecreasednjabilitynjofnjrednjbloodnjcellsnjtonjdealnjwithnjoxidativenjstress
Sarcoidosis,njAIDS
IBSnjD
MnjH
TN,
Kidneynjdisease,njAl
zheimer's,njProst
atenjcancer,njpan
creaticnjcancer
13.WhichnjofnjthenjfollowingnjconditionsnjisnjannjX-
linkednjrecessivenjdisordernjcom-njmonlynjseennjinnjAfricannjAmericannjmales?
1. Sicklenjcellnjanemia.
2. Glucose-6-phosphatenjdehydrogenasenjdeficiency.
3. Pyruvatenjkinasenjdeficiency.
4. Bernard-Souliernjsyndrome:nj2.njGlucose-6-
phosphatenjdehydrogenasenjdeficiency.
14.1.njSplenicnjsequestration/hypersplenismnjisnja
2. SignsnjandnjsymptomsnjofnjsplenicnjsequestrationnjHINT:nj(abdnjpain,njpalor,njtach
)
3. ManagementnjofnjSplenicnjsequestration
4. Earlynjrecognitionnjofnjsplenicnjsequestrationnjcannjbenjanjlifesavingnjskill.njPar-
njentsnjcannjbenjtaughtnjto:nj1.njfearednjcomplication njofnjsicklenjcellnjanemia njthat

njprimarilynjaffectsnjyoungnjchildren.njItnjisnjannjacutenjdropnjinnjhemoglobinnjofnj


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