KU BIOL 600 EXAM 2 FINAL 2025
QUESTIONS AND ANSWERS
Why is triacylglycerol a more efficient storage form of energy compared to glycogen? -
ANS Triacylglycerol is nonpolar or hydrophobic and excludes water doesn't absorb it thus
lighter more energy per weight-more efficient
• Glycogen absorbs water is heavier because of water less energy per weight
Draw A double-reciprocal plot for a noncompetitive inhibition
Indicate which line is with and without inhibitor - ANS Lower Vmax
Km unchanged
Can't be overcome by increasing substrate concentration
What is a competitive inhibition plot defined and look like? - ANS inhibitor binds where
substrate binds, can be relieved by increasing the substrate- example Sulfa Drug
Larger Km Vmax Unchanged
What is a uncompetitive inhibition plot? - ANS binds only to ES complex, lower vmax, lower
km
Can't be overcome by more substrate
What are Lectins and what do they bind? - ANS lectins are proteins that bind carbohydrates
or sugars
In sickle-cell anemia amino acid ___GLU___ is mutated into _?____ - ANS VAL
1 Copyright ©2025 THESTAR ALL RIGHTS RESERVED
, Glu mutated into VAL causes ? - ANS Sickle-cell anemia
Why do we have an optimum pH? - ANS • Because there are 5 ionizable amino acids
HISTIDINE, ASPARTATE, GLUTAMATE, LYSINE, ARGININE
Hemoglobin with the proximal histadine mutated to glycine can bind oxygen when supplied
with imidazole. Draw the oxygen-binding curve - ANS (Has to be hyperbolic) - PROX. HIS can
be replaced by Glycine
NOT SIGMOIDAL
In hemoglobin what happens to the heme upon binding to oxygen? - ANS • Heme flattens
upon being to oxygen
or Fe becomes smaller and goes into plane of heme
What does hemagglutinin bind to on the surface of host cells?
Hemmagglutinin is on surface of influenze - ANS • Binds to sialic acid (sugar) that has a COO-
group which makes it acidic
Explain how anomers are formed? - ANS • Linear→ Cyclic form forms new chiral center
(cyclization of sugars)
Example of epimers? - ANS Glucose and mannose- differ in only 1 chiral carbon
Both cellulose and starch are polysaccharides of glucose.
2 Copyright ©2025 THESTAR ALL RIGHTS RESERVED
QUESTIONS AND ANSWERS
Why is triacylglycerol a more efficient storage form of energy compared to glycogen? -
ANS Triacylglycerol is nonpolar or hydrophobic and excludes water doesn't absorb it thus
lighter more energy per weight-more efficient
• Glycogen absorbs water is heavier because of water less energy per weight
Draw A double-reciprocal plot for a noncompetitive inhibition
Indicate which line is with and without inhibitor - ANS Lower Vmax
Km unchanged
Can't be overcome by increasing substrate concentration
What is a competitive inhibition plot defined and look like? - ANS inhibitor binds where
substrate binds, can be relieved by increasing the substrate- example Sulfa Drug
Larger Km Vmax Unchanged
What is a uncompetitive inhibition plot? - ANS binds only to ES complex, lower vmax, lower
km
Can't be overcome by more substrate
What are Lectins and what do they bind? - ANS lectins are proteins that bind carbohydrates
or sugars
In sickle-cell anemia amino acid ___GLU___ is mutated into _?____ - ANS VAL
1 Copyright ©2025 THESTAR ALL RIGHTS RESERVED
, Glu mutated into VAL causes ? - ANS Sickle-cell anemia
Why do we have an optimum pH? - ANS • Because there are 5 ionizable amino acids
HISTIDINE, ASPARTATE, GLUTAMATE, LYSINE, ARGININE
Hemoglobin with the proximal histadine mutated to glycine can bind oxygen when supplied
with imidazole. Draw the oxygen-binding curve - ANS (Has to be hyperbolic) - PROX. HIS can
be replaced by Glycine
NOT SIGMOIDAL
In hemoglobin what happens to the heme upon binding to oxygen? - ANS • Heme flattens
upon being to oxygen
or Fe becomes smaller and goes into plane of heme
What does hemagglutinin bind to on the surface of host cells?
Hemmagglutinin is on surface of influenze - ANS • Binds to sialic acid (sugar) that has a COO-
group which makes it acidic
Explain how anomers are formed? - ANS • Linear→ Cyclic form forms new chiral center
(cyclization of sugars)
Example of epimers? - ANS Glucose and mannose- differ in only 1 chiral carbon
Both cellulose and starch are polysaccharides of glucose.
2 Copyright ©2025 THESTAR ALL RIGHTS RESERVED
