AND ANSWERS
The second round of fa synthesis involves the condensation reaction of __________ and
__________ - ANS malonyl acp, butyryl acp
the reaction of acetyl acp with malonyl acp produces a __________ compound
calledacetoacetyl acp - ANS 4 c
fa synthesis requires what for molecules - ANS acetyl coa, atp, co2, nadph
fa synthase is multifunctional enzyme where all the components are located on a polypeptide
chin but exists a __________ dimer - ANS single, homo
the er performs what two key functions in fa synthesis - ANS elongation past c16, introduces
double bonds into saturated fa
phosphatidate is converted to __________ as the active precursor to the synthesis of cadiolipin
and phosphotidylinositol 4,5-bisphosphate - ANS cdp diacylglycerol
if an alcohol is the active precursor and not diacylglycerol, the phospholipids __________ and
__________ are synthesized - ANS phosphatidylethanoalamine, phosphatidylcholine
ceramide has __________ as its backbone structure instead of glycerol - ANS sphingosine
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, the key regulatory enzyme in lipid synthesis is - ANS phosphatidic acid phosphatase
what are the three stages of cholesterol - ANS mevalonate to isopentyl pyrophosphate, six
molecules of isopentyl pyrophosphate are condensed to squalene, squalene is cyclized and
converted into cholesterol
how does the formation of ketone bodies contribute to cholesterol synthesis - ANS with the
breakdown of fatty acids into ketone bodies which are then converted to acetoacetyl coa,
which can then react with acetyl coa to form the precursor of cholesterol, called hmc coa
one regulation method is transcriptional regulation. describe this process when cholesterol
levels are low - ANS when cholesterol levels are low the scap protein attached to the srebp
proteins move to the golgi complex where the srebp is cleaved twice to cleave off the sre. sre
then moves to the nucleus and binds to dna resulting in the increase of those enzymes involved
in cholesterol production
what separates ldl's from hdl's - ANS ldl's have a higher lipid/protein ratio than hdl's
ldl's are delivered into the cellular cytoplasm by what method - ANS receptor mediated
endocytosis
what vitamin made from cholesterol uses sunlight for its synthesis - ANS vitamin d
name enzymes involved in the digestion of fats - ANS lipases
name enzymes involved in the digestion of proteins - ANS trypsin, chymotrypsin, pepsin
name enzymes involved in the digestion of starch - ANS elastase
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