KU BIOL 600 EXAM 3 2025 QUESTIONS
AND ANSWERS
Which enzymes catalyze the synthesis of phosphoenolpyruvate from pyruvate and a phosphate
group during gluconeogenesis? - ANS pyruvate carboxylase and phosphoenol pyruvate
carboxykinase
What mitochondrial transport protein is utilized during the synthesis of phosphoenolpyruvate
from pyruvate and a phosphate group during gluconeogenesis? - ANS malate transporter
Prior to entry of gluconeogenesis, ________ is converted into pyruvate, and some _________
are converted to oxaloacetate - ANS lactate and amino acids
What are the three inhibitors of phophofructosekinase? - ANS ATP Citrate and H+
In gluconeogenesis, name the two inhibitors of fructose 1,6 bisphosphate - ANS AMP and
fructose 2,6 bisphosphate
In gluconeogenesis, pyruvate carboxylase is inhibited by _______ and stimulated by _________
- ANS ADP and acetyl coA
Complete this sentence that describes the Cori Cycle: ______ from ______ is transported in
________ to the ______ where it is converted to glucose - ANS lactate muscle blood liver
Pyvurate carboxylase requires the vitamin cofactor ____, which serves as a carrier of activated
CO2 - ANS biotin
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, What peptide hormone is released when blood glucose concentration is low? - ANS glucagon
This stimulates the increase of ______ which stimulates ______ and inhibits ________ - ANS
Where is glucose-6-phosphatase found? what does it supply? - ANS ER
Glucose
What is pyruvate carboxylase activated by? - ANS Acetyl CoA
What is pyruvate carboxylase inhibited by? - ANS ADP
What is the substrate for glycogen synthesis? - ANS UDP-glucose
What is the role of glycogenin? - ANS It makes the primer for glycogen synthesis
What is the enzyme that removes glucose units from the non-reducing ends of the glycogen
molecule called? - ANS glycogen phosphorylase
Glycogen phosphorylase is activated by what protein modification - ANS phosphorylation
What two hormones maintain blood glucose levels within a normal range? - ANS insulin and
glucagon
How does protein phosphate 1 regulate glycogen phosphorylate? - ANS by removing the
phosphate group from glycogen synthase, which activates glycogen synthase
2 Copyright ©2025 THESTAR ALL RIGHTS RESERVED
AND ANSWERS
Which enzymes catalyze the synthesis of phosphoenolpyruvate from pyruvate and a phosphate
group during gluconeogenesis? - ANS pyruvate carboxylase and phosphoenol pyruvate
carboxykinase
What mitochondrial transport protein is utilized during the synthesis of phosphoenolpyruvate
from pyruvate and a phosphate group during gluconeogenesis? - ANS malate transporter
Prior to entry of gluconeogenesis, ________ is converted into pyruvate, and some _________
are converted to oxaloacetate - ANS lactate and amino acids
What are the three inhibitors of phophofructosekinase? - ANS ATP Citrate and H+
In gluconeogenesis, name the two inhibitors of fructose 1,6 bisphosphate - ANS AMP and
fructose 2,6 bisphosphate
In gluconeogenesis, pyruvate carboxylase is inhibited by _______ and stimulated by _________
- ANS ADP and acetyl coA
Complete this sentence that describes the Cori Cycle: ______ from ______ is transported in
________ to the ______ where it is converted to glucose - ANS lactate muscle blood liver
Pyvurate carboxylase requires the vitamin cofactor ____, which serves as a carrier of activated
CO2 - ANS biotin
1 Copyright ©2025 THESTAR ALL RIGHTS RESERVED
, What peptide hormone is released when blood glucose concentration is low? - ANS glucagon
This stimulates the increase of ______ which stimulates ______ and inhibits ________ - ANS
Where is glucose-6-phosphatase found? what does it supply? - ANS ER
Glucose
What is pyruvate carboxylase activated by? - ANS Acetyl CoA
What is pyruvate carboxylase inhibited by? - ANS ADP
What is the substrate for glycogen synthesis? - ANS UDP-glucose
What is the role of glycogenin? - ANS It makes the primer for glycogen synthesis
What is the enzyme that removes glucose units from the non-reducing ends of the glycogen
molecule called? - ANS glycogen phosphorylase
Glycogen phosphorylase is activated by what protein modification - ANS phosphorylation
What two hormones maintain blood glucose levels within a normal range? - ANS insulin and
glucagon
How does protein phosphate 1 regulate glycogen phosphorylate? - ANS by removing the
phosphate group from glycogen synthase, which activates glycogen synthase
2 Copyright ©2025 THESTAR ALL RIGHTS RESERVED
