2025 Actual with Questions & Answers (Latest
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1. Morphine:Opioid agonist:binds to the opioid mu-1 and mu-2 and kappa
y
g gy y
g gy gy gy gy gy gy gy gy
receptors in the CNS and alters pain perception and response
gy gy gy gy gy gy gy gy gy gy
Sideeffects:confusion,sedation,constipation,hypotension,respiratorydepression
y
g y
g y
g y
g y
g y
g y
g
Antidote= naloxene
gy gy
2. •Demerol:Opioidagonistmu-1andmu-2andkappareceptors. side
gy y
g gy gy gy gy gy gy gy gy
effects:
gy
-Nausea
- Vomiting
- Euphoria
- Dysphoria
gy gy
, - RespiratoryDepression y
g
Adverse effect: seizures
gy gy gy
Antidote= naloxene
gy gy
3. • Ativan gy
• :Potentiates action of GABA, resulting in increased neuronal inhibition and CNS
y
g gy gy gy gy gy gy gy gy gy gy
gy depression,
Side effects: gy
CNS:dizziness,drowsiness,lethargy,hangover,headache,ataxia,slurredspeech,
y
g y
g y
g y
g y
g y
g y
g y
g
forgetfulness, confusion, mental depression,
gy gy gy gy
4. Dilantin: 1. Anticonvulsant: stabilizes neuronal membranes and limits seizure
y
g y
g y
g gy gy gy gy gy
activity by either increasing efflux or decreasing influx of sodium ions across cell
gy gy gy gy gy gy gy gy gy gy gy gy gy
membranes in the motor cortex during generation of nerve impulses.
gy gy gy gy gy gy gy gy gy gy
2.Antiarrhythmic:normalizes sodium influx to Purkinje's fibers in patients with induced
y
g y
g gy gy gy gy gy gy gy gy gy
dysrhythmias.
gy
Side effects: gy
1. nausea, vomiting gy
2. CNS depression gy
3. respiratory depression gy
4. heart blocks g y
5. hypotension
6. dysrhythmias
5. • Nitroglycerine:-Reducesvenoustone.(Bloodpoolinginperiphveins,decreas- ing
gy gy y
g y
g y
g y
g y
g y
g y
g y
g gy
venous return to the heart.
gy gy gy gy gy
-Decreased periph.vascular resistance. gy y
g gy
-Dilation of coronary arteries and relief of coronary artery spasm.
gy gy gy gy gy gy gy gy gy
-Vasodilation of cerebral arteries, increasing O2 to brain. gy gy gy gy gy gy gy
gy gy