Top 50 Drugs- ATI Pharm Questions &
Answers Correct/ Verified
Celecoxib - ANSWER-NSAIDs, COX-2 inhibitor
Therapeutic Effects: Analgesic, anti- inflammatory, & anti- pyretic
A/R: GI BLEEDING, dermal rash, GI effects
Assess pain, ROM and swelling. Do not give if allergic to sulfonamides, aspirin or
NSAIDs. Watch for tarry stools.
Losartan - ANSWER-Classification: Angiotensin II receptor blocker
Therapeutic Effects: Antihypertensive. Decreases risk of stroke.
A/R & S/E:
Orthostatic hypotension, diarrhea. Dizziness, ANGIOEDEMA. Use cautiously in CHF
Nursing Implications & teaching: Assess orthostatic blood pressures. Use care when
changing positions to prevent orthostatic hypotension. Monitor BUN/Creatinine for
possible early renal failure.
Warfarin - ANSWER-Classification:Anticoagulant. Interferes with hepative syntheses of
Vitamin K- dependant clotting factors
Therapeutic Effects: Prophylaxis/Treatment of venous &/or pulmonary embolism (PE)
and atrial fibrillation w/ embolization. Antidote = Vitamin K
Adverse Reactions & side effects: Bleeding. Numerous drugs and natural products
affect the activity of warfarin!
Nursing Implications & teaching: Asses for bleeding, or increased thrombosis. Check
INR/PT before administration and regularly. PT may be 1.3-1.5 times greater than
control. INR goal dependent on medical diagnosis. Maintain consistent vitamin K, Take
in evening. Avoid ETOH & OTC medications. High Alert Medication
Prednisone - ANSWER-Anti-inflammatory (intermediate acting) corticosteroid
Therapeutic Effects: inflammation & modification of the normal immune response;
replacement therapy in adrenal insufficiency. Management of cerebral edema.
Potentiates anti-N/V action of Zofran.
A/R: PEPTIC ULCERATION, THROMBOEMBOLISM, mood changes, hypertension,
anorexia, nausea, acne, decreased wound healing, ecchymosis, fragility, hirsutism,
petechiae, adrenal suppression, muscle wasting, osteoporosis, cushingoid appearance,
GI effects
, Monitor for: fluid retention, hyperglycemia, infections, bleeding, steady weight gain,
crackles, dyspnea.
Do not D/C abruptly. Monitor serum electrolytes, cholesterol/lipids
Avoid people w/contagious illnesses, TAKE WITH FOOD
Dexamethasone - ANSWER-Anti-inflammatory (long acting) corticosteroid
Therapeutic Effects: inflammation & modification of the normal immune response;
replacement therapy in adrenal insufficiency. Management of cerebral edema.
Potentiates anti-N/V action of Zofran.
Adverse Reactions & side effects: PEPTIC ULCERATION, THROMBOEMBOLISM,
mood changes, hypertension, anorexia, nausea, acne, decreased wound healing,
ecchymosis, fragility, hirsutism, petechiae, adrenal suppression, muscle wasting,
osteoporosis, cushingoid appearance, GI effects
Nursing Implications & teaching:Monitor for fluid retention, hyperglycemia, infections,
bleeding, steady weight gain, crackles, dyspnea. Do not D/C abruptly. Monitor serum
electrolytes, cholesterol/lipids. avoid people w/contagious illnesses, TAKE WITH FOOD
Phenytoin - ANSWER-Antiarrhythmic/ Anticonvulsant
Therapeutic Effects: Decrease seizures & pain, control arrhythmias
A/R: Aganulocytosis, aplastic anemia, Stevens-Johnson syndrome. diplopia,
nystagmus, hypotension, gingival hyperplasia, nausea, rashes
Nursing Implications & teaching: Assess for hypersensitivity syndrome; monitor CBC,
platelet count, avoid driving till MD ok; avoid ETOH & OTC meds; maintain oral hygiene;
urine can be pink/red;
Diabetic-monitor glucose closely;
Avoid taking within 2-3hr of antacids/antidiarrheals; decrease contraceptive(hormonal),
TAKE WITH FOOD
Metronidazole (Flagyl) - ANSWER-Antiinfective, antiulcer, Antiprotozoal
Therapeutic Effects: Treatment of anaerobic and parasitic infections
A/R: SEIZURES, dizziness, HA, anorexia, nausea, GI effects
Monitor WBC, neurological status, and I/Os, TAKE WITH FOOD
Tamsulosin (Flomax) - ANSWER-Classification: Peripherally acting anti-adrenergic.
Therapeutic Effects: Decreased symptoms of prostatic hyperplasia, i.e. male urinary
outflow obstruction
Adverse Reactions & side effects: Dizziness, headache, orthostatic hypotension,
retrograde/ diminished ejaculation. Cautious in patients at risk for prostate carcinoma
Nursing Implications & teaching: Monitor for dizziness, hypotension. Have patient
change positions slowly to minimize symptoms.
Alendronate - ANSWER-Bone resorption inhibitor. Bisphosphonate
Therapeutic Effects: TX and prevention of post-menopausal and cortico-steroid-induced
osteoporosis,
Answers Correct/ Verified
Celecoxib - ANSWER-NSAIDs, COX-2 inhibitor
Therapeutic Effects: Analgesic, anti- inflammatory, & anti- pyretic
A/R: GI BLEEDING, dermal rash, GI effects
Assess pain, ROM and swelling. Do not give if allergic to sulfonamides, aspirin or
NSAIDs. Watch for tarry stools.
Losartan - ANSWER-Classification: Angiotensin II receptor blocker
Therapeutic Effects: Antihypertensive. Decreases risk of stroke.
A/R & S/E:
Orthostatic hypotension, diarrhea. Dizziness, ANGIOEDEMA. Use cautiously in CHF
Nursing Implications & teaching: Assess orthostatic blood pressures. Use care when
changing positions to prevent orthostatic hypotension. Monitor BUN/Creatinine for
possible early renal failure.
Warfarin - ANSWER-Classification:Anticoagulant. Interferes with hepative syntheses of
Vitamin K- dependant clotting factors
Therapeutic Effects: Prophylaxis/Treatment of venous &/or pulmonary embolism (PE)
and atrial fibrillation w/ embolization. Antidote = Vitamin K
Adverse Reactions & side effects: Bleeding. Numerous drugs and natural products
affect the activity of warfarin!
Nursing Implications & teaching: Asses for bleeding, or increased thrombosis. Check
INR/PT before administration and regularly. PT may be 1.3-1.5 times greater than
control. INR goal dependent on medical diagnosis. Maintain consistent vitamin K, Take
in evening. Avoid ETOH & OTC medications. High Alert Medication
Prednisone - ANSWER-Anti-inflammatory (intermediate acting) corticosteroid
Therapeutic Effects: inflammation & modification of the normal immune response;
replacement therapy in adrenal insufficiency. Management of cerebral edema.
Potentiates anti-N/V action of Zofran.
A/R: PEPTIC ULCERATION, THROMBOEMBOLISM, mood changes, hypertension,
anorexia, nausea, acne, decreased wound healing, ecchymosis, fragility, hirsutism,
petechiae, adrenal suppression, muscle wasting, osteoporosis, cushingoid appearance,
GI effects
, Monitor for: fluid retention, hyperglycemia, infections, bleeding, steady weight gain,
crackles, dyspnea.
Do not D/C abruptly. Monitor serum electrolytes, cholesterol/lipids
Avoid people w/contagious illnesses, TAKE WITH FOOD
Dexamethasone - ANSWER-Anti-inflammatory (long acting) corticosteroid
Therapeutic Effects: inflammation & modification of the normal immune response;
replacement therapy in adrenal insufficiency. Management of cerebral edema.
Potentiates anti-N/V action of Zofran.
Adverse Reactions & side effects: PEPTIC ULCERATION, THROMBOEMBOLISM,
mood changes, hypertension, anorexia, nausea, acne, decreased wound healing,
ecchymosis, fragility, hirsutism, petechiae, adrenal suppression, muscle wasting,
osteoporosis, cushingoid appearance, GI effects
Nursing Implications & teaching:Monitor for fluid retention, hyperglycemia, infections,
bleeding, steady weight gain, crackles, dyspnea. Do not D/C abruptly. Monitor serum
electrolytes, cholesterol/lipids. avoid people w/contagious illnesses, TAKE WITH FOOD
Phenytoin - ANSWER-Antiarrhythmic/ Anticonvulsant
Therapeutic Effects: Decrease seizures & pain, control arrhythmias
A/R: Aganulocytosis, aplastic anemia, Stevens-Johnson syndrome. diplopia,
nystagmus, hypotension, gingival hyperplasia, nausea, rashes
Nursing Implications & teaching: Assess for hypersensitivity syndrome; monitor CBC,
platelet count, avoid driving till MD ok; avoid ETOH & OTC meds; maintain oral hygiene;
urine can be pink/red;
Diabetic-monitor glucose closely;
Avoid taking within 2-3hr of antacids/antidiarrheals; decrease contraceptive(hormonal),
TAKE WITH FOOD
Metronidazole (Flagyl) - ANSWER-Antiinfective, antiulcer, Antiprotozoal
Therapeutic Effects: Treatment of anaerobic and parasitic infections
A/R: SEIZURES, dizziness, HA, anorexia, nausea, GI effects
Monitor WBC, neurological status, and I/Os, TAKE WITH FOOD
Tamsulosin (Flomax) - ANSWER-Classification: Peripherally acting anti-adrenergic.
Therapeutic Effects: Decreased symptoms of prostatic hyperplasia, i.e. male urinary
outflow obstruction
Adverse Reactions & side effects: Dizziness, headache, orthostatic hypotension,
retrograde/ diminished ejaculation. Cautious in patients at risk for prostate carcinoma
Nursing Implications & teaching: Monitor for dizziness, hypotension. Have patient
change positions slowly to minimize symptoms.
Alendronate - ANSWER-Bone resorption inhibitor. Bisphosphonate
Therapeutic Effects: TX and prevention of post-menopausal and cortico-steroid-induced
osteoporosis,
