GMS 6401 TEST 1 QUESTIONS AND 100% VERIFIED CORRECT ANSWERS!!

GMS 6401 TEST 1 QUESTIONS AND 100%
VERIFIED CORRECT ANSWERS!!
where is 99% of total body calcium found

in ICF/bone

what % of renal calcium is bound to protein

40%

what % of renal calcium is filterable

60%
mostly ionized

calcium reabsorption in the proximal tubule

-65-70%
-bulk reabsorption so not regulated
-mostly passive, paracellular reabsorption
-driven by sodium reabsorption

calcium reabsorption in the TALH

-20-25%
-passive, paracellular
-driven by lumen + transepithelial
-generated by K+ reabsorption/secretion vis the NKCC2/ROMK channels
-major site of regulation

calcium reabsorption in the distal nephron

-9% reabsorbed
-active reabsorption, via luminal calcium channels
-major site of regulation

what helps increase calcium reabsorption in the TALH and distal tubule

, -PTH (most important)
-calciferol/1-25 (OH)2 vitamin D
-calcitonin

what inhibits calcium reabsorption in the kidney

-high plasma calcium bc it activates the calcium sensing receptor
-this inhibits NKCC2
-furosemide also inhibits reabsorption

what is given to people who form calcium stones

-thiazide diuretics
-they inhibit distal tubule NaCl reabsorption

where is most of the phosphate in the body found

85% is found in bone
14% is in cells
less than 1% is in ECF

what % of plasma phosphate is freely filtered

90%

proximal tubule phosphate reabsorption

-80%
-through secondary, active co-transport with sodium

what can decrease phosphate reabsorption

-PTH

what is phosphaturia

when phosphate is in the urine

how does phosphate behave in the collecting duct