BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION
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KATZUNG TREVOR TEST BANK
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INCLUSIVE lOF lCHAPTERS l1-66 lCOMPLETE lWITH lEXPLAINED lANSWERS
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapter l1. lIntroduction: lThe lNature lof lDrugs l& lDrug lDevelopment l& lRegulation
1. A lnurse lworking lin lradiology ladministers liodine lto la lpatient lwho lis lhaving
la lcomputed ltomography l(CT) lscan. lThe lnurse lworking lon lthe loncology
lunit ladministers lchemotherapy lto lpatients lwho lhave lcancer. lAt lthe lPublic
lHealth lDepartment, la lnurse ladministers la lmeasles-mumps-rubella l(MMR)
lvaccine lto la l14-month-old lchild las la lroutine limmunization. lWhich lbranch
lof lpharmacology lbest ldescribes lthe lactions lof lall lthree l nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
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Pharmacology lis lthe lstudy lof lthe lbiologic leffects lof lchemicals. lNurses lare
linvolved lwith lclinical lpharmacology lor lpharmacotherapeutics, lwhich lis la
lbranch lof lpharmacology lthat ldeals lwith lthe luses lof ldrugs lto ltreat, lprevent,
land ldiagnose ldisease. lThe lradiology lnurse lis ladministering la ldrug lto lhelp
ldiagnose la ldisease. lThe loncology lnurse lis ladministering la ldrug lto lhelp ltreat
la ldisease. lPharmacoeconomics lincludes lany lcosts linvolved lin ldrug
ltherapy.
Pharmacodynamics linvolves lhow la ldrug laffects lthe lbody land
lpharmacokinetics lis lhow lthe lbody lacts lon lthe lbody.
2. When linvolved lin lphase lIII ldrug levaluation lstudies,
lwhat lresponsibilities lwould lthe lnurse lhave?
A) Working lwith lanimals lwho lare lgiven lexperimental l drugs
B) Choosing lappropriate lpatients lto lbe linvolved lin lthe ldrug l study
C) Monitoring land lobserving lpatients lclosely lfor ladverse l effects
D) Conducting lresearch lto ldetermine leffectiveness lof lthe l drug
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Ans: C
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Phase lIII lstudies linvolve luse lof la ldrug lin la lvast lclinical lpopulation lin
lwhich lpatients lare lasked lto lrecord lany lsymptoms lthey lexperience lwhile
ltaking lthe ldrugs. lNurses lmay lbe lresponsible lfor lhelping lcollect l and
lanalyze l the linformation lto lbe lshared lwith lthe lFood land lDrug
lAdministration l(FDA) lbut lwould lnot lconduct lresearch lindependently
lbecause lnurses ldo lnot lprescribe lmedications. lUse lof lanimals lin ldrug
ltesting lis ldone l in lthe lpreclinical ltrials. lSelect lpatients lwho lare linvolved lin
lphase lII lstudies lto lparticipate lin lstudies lwhere lthe l participants lhave lthe
ldisease lthe ldrug lis l intended lto ltreat. lThese lpatients lare lmonitored lclosely
lfor ldrug laction land ladverse leffects. lPhase lI lstudies linvolve lhealthy lhuman
lvolunteers lwho lare lusually lpaid lfor ltheir lparticipation. lNurses lmay
lobserve lfor ladverse leffects land ltoxicity.
3. A lphysician lhas lordered lintramuscular l(IM) linjections lof lmorphine, la
lnarcotic, levery l4 lhours las lneeded lfor lpain lin la lmotor lvehicle laccident
lvictim. lThe lnurse lis laware lthis ldrug lhas la lhigh labuse lpotential. lUnder
lwhat lcategory lwould lmorphine lbe lclassified?
A) Schedule lI
B) Schedule lII
C) Schedule lIII
D) Schedule lIV
Ans: B
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Narcotics lwith la lhigh labuse lpotential lare lclassified las lSchedule lII ldrugs
lbecause lof lsevere ldependence lliability. lSchedule lI l drugs lhave lhigh labuse
lpotential land lno laccepted lmedical luse. lSchedule lIII ldrugs lhave la llesser
labuse lpotential lthan lII land lan laccepted lmedical luse. lSchedule lIV ldrugs
lhave llow labuse lpotential land llimited ldependence lliability.
4. What lconcept lis lconsidered lwhen lgeneric ldrugs lare lsubstituted lfor lbrand
lname ldrugs?
A) Bioavailability
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