CSO study guide/CSO Exam With complete solution 100% verified correct 2025/2026

CSO study guide/CSO Exam With complete solution
100% verified correct 2025/2026
*chemo-Epoetin alpha - Correct Answers Immunologic-hematopoietic Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




erthropoietin, EPO. Used to increase production of RBCs in the treatment of fatigue, anemia.
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fever, iron supplementation may be necessary
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Il` *chemo-Filgastrim - Correct Answers Immunologic-hematopoietic Il` Il` Il` Il` Il` Il` Il` Il` Il`




granulocytic colony-stimulating factor, G-CSF, stimulates production of WBC's.
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Fever, bone pain, flulike symptoms
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Il` *chemo-Monoclonal antibodies - Correct Answers Immunologic-biologic response modifiers Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




Rituximab, trastuzumab Il`




Myelosuppression, anorexia, N/V, fever, chills, rash Il` Il` Il` Il` Il`




Il` *chemo-Sargramostin - Correct Answers Immunologic-hematopoietic Il` Il` Il` Il` Il` Il` Il` Il` Il`




granulocytic macrophage-stimulating factor, GM-CSF Il` Il` Il`




Fever, bone pain, flulike symptoms
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Il` 5-Fluoracil (5-FU) - Correct Answers Low emetogenic
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Moderate myelosuppresion Il`




Severe--mucositis/esophagitis

Diarrhea, renal effects Il` Il`




Il` adjuvant - Correct Answers use of additional cancer treatment after the primary therapy
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,Il` Ageusia - Correct Answers Loss or absence of the sense of taste
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Il` Allogenic marrow transplantation - Correct Answers Transfer of marrow from donor to another
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Il` person who is not genetically identical
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Il` antiemetics : butyrophenone (Dopamine agonists) Il` Il` Il` Il`




droperidol/inapsine

haloperidol/haldol - Correct Answers side effects: Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




sedation

EPS

droperidol is more sedating Il` Il` Il`




Il` antiemetics-5-HT3 serotonin antagonists Il` Il`




dolasetron/anzemet

granisetron/kytril

ondansetron/zofran - Correct Answers most effective in the prevention and treatment of Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




chemotherapy-induced nausea and vomiting (CINV), esp caused by highly emetogenic drugs such
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as cisplatin; when used for this purpose, they may be given alone or, more frequently, with
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glucocorticoid, usually dexamethasone.
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They are usually given intravenously, shortly before administration of the chemotherapeutic
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agent. The concomitant administration of a NK1 receptor antagonist, such as aprepitant,
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increases the efficacy of 5-HT3 antagonists in preventing both acute and delayed CINV.
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The 5-HT3 antagonists are also indicated in the prevention and treatment of radiation-induced
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nausea and vomiting (RINV) and post-op nausea and vomiting (PONV).
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,side effects: headache, diarrhea, constipation, possible EKG changes, somnolence
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Il` antiemetics, guideline for use: - Correct Answers An antiemetic regimen administered before
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Il` chemotherapy is recommended to prevent acute nausea and vomiting. This three-drug
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Il` combination is recommended by ASCO (American Society of Clinical Oncology) for highly
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Il` emetogenic chemotherapy medications: Il` Il`




1. Serotonin 5-HT3 receptor antagonist (Ondansetron, dolasetron, granisetron, palonosetron)
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2. Dexamethasone (corticosteroid)
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3. Aprepitant (NK1 receptor antagonist)
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Il` antiemetics: anticholernigics (anticholinergic)
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scopolamine transderm patch - Correct Answers side effects:
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urinary retention Il`




dry eyes Il`




constipation



effective for nausea related to motion, useful with bowel obstructions
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Il` antiemetics: benzamides (Dopamine agonists or 5HT3)
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metoclopramide/reglan - Correct Answers dopamine agonist or 5HT3 at high doses Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




side effects: Il`




sedation

fatigue

diarrhea

nausea

, also used in early satiety and anorexia
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Il` antiemetics: benzodiazepines (benzodiazepine) Il` Il`




lorazapam/ativan

diazepam/valium - Correct Answers side effects: Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




sedation

confusion

amnesia

slurred speech Il`




effective for anticipatory nausea/anxiety. Lorazepam may be placed under the tongue.
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Il` antiemetics: cannabinoids (unknown mechanism) Il` Il` Il`




dronabinol/marinol - Correct Answers side effects: Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




mood changes (vivid dreams)
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increased appetite Il`




hypotension

tachycardia



well tolerated in younger patients, may be crushed. Less tolerated in older patients.
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Il` antiemetics: corticosteroids (unknown mechanism of action)
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dexamethasone/decadron - Correct Answers side effects: Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




increased appetite Il`




anxiety

mood changes Il`