PHARMACOLOGY NBME EXAM
2025 QUESTIONS AND ANSWERS
Types of smooth muscle - ....ANSWER ...-vasculature
bladder
reproductive tracts
GI tract
respiratory tract
skin
eye
Types of Muscarinic receptors - ....ANSWER ...-M1, M2, M3
QIQ
Location and function of M1 - ....ANSWER ...-multiple functions in Nerve
endings
Location and function of M2 - ....ANSWER ...-decelerates the heart rate
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 1
,Location and function of M3 - ....ANSWER ...-contracts smooth muscle
including bladder wall and bronchi
relaxes sphincters (increases GI motility)
increases secretions in glands
vasodilates
contracts the circular and ciliary muscle for near vision accommodation
Location and function of alpha1 - ....ANSWER ...-constricts smooth muscle
and sphincters
Location and function of alpha2 - ....ANSWER ...-decreases transmitter
release at nerve endings
Location and function of beta1 - ....ANSWER ...-increases heart rate and
contractibility in cardiac muscle
Increases renin secretion in kidney
Location and function of beta2 - ....ANSWER ...-relaxes smooth muscle
including bronchi and bladder wall,
increases glucose availability in liver and skeletal muscle
Location and function of beta3 - ....ANSWER ...-increases lipolysis in
adipose
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 2
, Tone at rest - ....ANSWER ...-most organs are controlled by PNS but
cardiac ventricle and vascular smooth muscle are controlled by SNS
Different effects on receptors for epinephrine and norepinephrine -
....ANSWER ...-Epinephrine can act on B2 receptors along with alpha and
beta1
But norepinephrine cannot act on B2
SLUD-BBAM - ....ANSWER ...-Salivation
Lacrimation
Urination
Diarrhea
Bradycardia
Bronchoconstriction
Abdominal Cramps
Miosis
Direct Acting Muscarinic Agonists effect - ....ANSWER ...-Induce PNS like
control (SLUD-BBAM)
Direct Acting Muscarinic Agonists - ....ANSWER ...-Bethanechol- ileus and
urinary rentention
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 3
2025 QUESTIONS AND ANSWERS
Types of smooth muscle - ....ANSWER ...-vasculature
bladder
reproductive tracts
GI tract
respiratory tract
skin
eye
Types of Muscarinic receptors - ....ANSWER ...-M1, M2, M3
QIQ
Location and function of M1 - ....ANSWER ...-multiple functions in Nerve
endings
Location and function of M2 - ....ANSWER ...-decelerates the heart rate
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 1
,Location and function of M3 - ....ANSWER ...-contracts smooth muscle
including bladder wall and bronchi
relaxes sphincters (increases GI motility)
increases secretions in glands
vasodilates
contracts the circular and ciliary muscle for near vision accommodation
Location and function of alpha1 - ....ANSWER ...-constricts smooth muscle
and sphincters
Location and function of alpha2 - ....ANSWER ...-decreases transmitter
release at nerve endings
Location and function of beta1 - ....ANSWER ...-increases heart rate and
contractibility in cardiac muscle
Increases renin secretion in kidney
Location and function of beta2 - ....ANSWER ...-relaxes smooth muscle
including bronchi and bladder wall,
increases glucose availability in liver and skeletal muscle
Location and function of beta3 - ....ANSWER ...-increases lipolysis in
adipose
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 2
, Tone at rest - ....ANSWER ...-most organs are controlled by PNS but
cardiac ventricle and vascular smooth muscle are controlled by SNS
Different effects on receptors for epinephrine and norepinephrine -
....ANSWER ...-Epinephrine can act on B2 receptors along with alpha and
beta1
But norepinephrine cannot act on B2
SLUD-BBAM - ....ANSWER ...-Salivation
Lacrimation
Urination
Diarrhea
Bradycardia
Bronchoconstriction
Abdominal Cramps
Miosis
Direct Acting Muscarinic Agonists effect - ....ANSWER ...-Induce PNS like
control (SLUD-BBAM)
Direct Acting Muscarinic Agonists - ....ANSWER ...-Bethanechol- ileus and
urinary rentention
....COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED...TRUSTED & VERIFIED 3