Perio II - Test 1 Questions and Answers Already Passed
blood - Answers mature lymphocytes are found where?
tissue - Answers mature dendritic cells are found where?
antibodies - Answers Extracellular pathogens are eliminated chiefly by ______________
T cells, macrophages - Answers intracellular pathogens require __________ and _____________ for
elimination.
cell-mediated immunity - Answers The function of T cells is sometimes referred to as
_________________
Antigen presenting cells - Answers __________________, such as dendritic cells in the skin and
macrophages are critical in initiating the activation of B and T cells.
neutrophils - Answers make up approximately 60% of all white blood cells
neutrophils - Answers most active phagocytic cells in the body
neutrophils - Answers serve as the primary effector cell in inflammation.
eosinophils - Answers destroy parasites and are a major component of allergic reactions.
basophils - Answers role is unclear although it is known that they release many of the chemicals involved
in the inflammatory process.
monocytes - Answers extremely phagocytic. Those that have left the blood stream and settled in the
tissues are called macrophages.
macrophages - Answers monocytes that have left the blood stream and settled in the tissues are called
_______________
B lymphocytes - Answers Antibodies, are the antigen-specific proteins produced by ________________
in response to contact with antigen.
antibodies - Answers _________________ circulate in the blood and lymph as plasma components
light, heavy - Answers antibodies are made up of what two chains?
2, 2 - Answers In the basic immunoglobulin, there are __________ heavy and _________ light chains
linked together by intermolecular bonds.
antigen - Answers The primary function of all antibodies is to bind to an ______________.
agglutination - Answers clumping together
, phagocytic cells - Answers If bacteria are coated with antibodies, this can enhance the likelihood that
they will be engulfed by ___________________
activate compliment & lytic - Answers Antibodies can also ____________________ and initiate a
_______________ reaction that destroys the cell to which the antibody is bound
IgM - Answers This is the predominant antibody early in an immune response.
IgM - Answers It has ten potential antigen-binding sites and because of this it is the most efficient
antibody at agglutinating bacteria and activating complement.
IgG - Answers This is the most prevalent antibody molecule in serum.
IgG - Answers survives intact in serum for the longest time (has the longest half-life), and it is able to
cross the placental to allow maternal protection of the newborn.
IgA - Answers This is the main immunoglobulin in secretions such as saliva, milk and tears, and it is
IgA - Answers immunoglobulin heavily represented in the mucosal epithelia of the respiratory, genital
and intestinal tracts.
IgD - Answers Chiefly found on the surface of B cells as a receptor molecule and is involved in cell
activation.
IgE - Answers Binding of ______ to an Fc receptor on mast cells and basophils in the presence of antigen
triggers an allergic reaction by the activation of the mast cell and release of mediators such as histamine.
IgE - Answers originally evolved to protective host response to foreign antigens.
virus - Answers CD8+ infection
bacteria - Answers CD4+ infection
adaptive immune response - Answers If a foreign organism or antigen (such as a toxin) gains entry, the
protective systems of the innate immune system (e.g., phagocytic cells) may destroy the antigen before
it is encountered by B or T cells and induces an _________________.
macrophags, B-cells, dendritic cells - Answers examples of antigen-presenting cells
CD4 - Answers helper T cell
CD8 - Answers cytotoxic T cell
II & I - Answers CD4 T cell-APC interaction is MHC class ________ restricted and the CD8 T cell-target cell
interaction is MHC class ________ restricted.
extracellular or exogenous antigen - Answers protein derived from a pathogen in a cytoplasmic vesicle
after uptake.
blood - Answers mature lymphocytes are found where?
tissue - Answers mature dendritic cells are found where?
antibodies - Answers Extracellular pathogens are eliminated chiefly by ______________
T cells, macrophages - Answers intracellular pathogens require __________ and _____________ for
elimination.
cell-mediated immunity - Answers The function of T cells is sometimes referred to as
_________________
Antigen presenting cells - Answers __________________, such as dendritic cells in the skin and
macrophages are critical in initiating the activation of B and T cells.
neutrophils - Answers make up approximately 60% of all white blood cells
neutrophils - Answers most active phagocytic cells in the body
neutrophils - Answers serve as the primary effector cell in inflammation.
eosinophils - Answers destroy parasites and are a major component of allergic reactions.
basophils - Answers role is unclear although it is known that they release many of the chemicals involved
in the inflammatory process.
monocytes - Answers extremely phagocytic. Those that have left the blood stream and settled in the
tissues are called macrophages.
macrophages - Answers monocytes that have left the blood stream and settled in the tissues are called
_______________
B lymphocytes - Answers Antibodies, are the antigen-specific proteins produced by ________________
in response to contact with antigen.
antibodies - Answers _________________ circulate in the blood and lymph as plasma components
light, heavy - Answers antibodies are made up of what two chains?
2, 2 - Answers In the basic immunoglobulin, there are __________ heavy and _________ light chains
linked together by intermolecular bonds.
antigen - Answers The primary function of all antibodies is to bind to an ______________.
agglutination - Answers clumping together
, phagocytic cells - Answers If bacteria are coated with antibodies, this can enhance the likelihood that
they will be engulfed by ___________________
activate compliment & lytic - Answers Antibodies can also ____________________ and initiate a
_______________ reaction that destroys the cell to which the antibody is bound
IgM - Answers This is the predominant antibody early in an immune response.
IgM - Answers It has ten potential antigen-binding sites and because of this it is the most efficient
antibody at agglutinating bacteria and activating complement.
IgG - Answers This is the most prevalent antibody molecule in serum.
IgG - Answers survives intact in serum for the longest time (has the longest half-life), and it is able to
cross the placental to allow maternal protection of the newborn.
IgA - Answers This is the main immunoglobulin in secretions such as saliva, milk and tears, and it is
IgA - Answers immunoglobulin heavily represented in the mucosal epithelia of the respiratory, genital
and intestinal tracts.
IgD - Answers Chiefly found on the surface of B cells as a receptor molecule and is involved in cell
activation.
IgE - Answers Binding of ______ to an Fc receptor on mast cells and basophils in the presence of antigen
triggers an allergic reaction by the activation of the mast cell and release of mediators such as histamine.
IgE - Answers originally evolved to protective host response to foreign antigens.
virus - Answers CD8+ infection
bacteria - Answers CD4+ infection
adaptive immune response - Answers If a foreign organism or antigen (such as a toxin) gains entry, the
protective systems of the innate immune system (e.g., phagocytic cells) may destroy the antigen before
it is encountered by B or T cells and induces an _________________.
macrophags, B-cells, dendritic cells - Answers examples of antigen-presenting cells
CD4 - Answers helper T cell
CD8 - Answers cytotoxic T cell
II & I - Answers CD4 T cell-APC interaction is MHC class ________ restricted and the CD8 T cell-target cell
interaction is MHC class ________ restricted.
extracellular or exogenous antigen - Answers protein derived from a pathogen in a cytoplasmic vesicle
after uptake.
