Walden 6630 Psychopharmacology Midterm Study Guide Questions with Detailed Verified Answers

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Walden 6630 Psychopharmacology
Midterm Study Guide Questions with
Detailed Verified Answers

Question: Serotonin regulates


Ans: Mood, emotion, feeding, and reproductive behavior


Question: This class of antidepressants binds to presynaptic SERT and
inhibits them from reuptake of serotonin to increase levels in the synaptic cleft
to bind with postsysnaptic 5HT2 receptors


Ans: SSRIs


Question: First line therapy for MDD due to milder side effect profiles


Ans: SSRIs


Question: Six Common SSRIs


Ans: citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline, paroxetine


Question: Onset of therapeutic benefit from SSRIs


Ans: 4-6 weeks

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Question: In addition to MDD, SSRIs also treat


Ans: Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)


Question: Five Common side effects of SSRIs include


Ans: Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH


Question: Severe side effect of SSRIs in children/adolescents under age 25
years old


Ans: suicidal ideation


Question: Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.)


Ans: Serotonin Syndrome


Question: Excess accumulation of serotonin resulting in overstimulation of
the nervous system


Ans: Serotonin Syndrome


Question: Seven symptoms of Serotonin Syndrome


Ans: Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia


Question: The treatment for serotonin syndrome

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Ans: Cyproheptadine (5-HT2 receptor antagonist)


Question: Cyproheptadine treats serotonin syndrome by


Ans: blocking 5-HT2 receptors (serotonin antagonist)


Question: When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include


Ans: Irritability, headaches, and insomnia


Question: Medicine specific side effect of citalopram


Ans: Prolonged QT interval (normal=0.4.-0.44 seconds)


Question: This SSRI is pregnancy category D due to associations with
congenital heart defects


Ans: Paroxetine


Question: All SSRIs but paroxetine (D) are pregnancy category


Ans: C


Question: Three SSRIs that are inhibitors of Cytochrome P450 enzymes


Ans: fluoxetine, fluvoxamine, and paroxetine


Question: Five common SNRIs include

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Ans: duloxetine, venlafaxine, desvenlafaxine, milnacipran, levomilnacipran


Question: This antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of serotonin and
norepinephrine to increase their levels in the synaptic cleft


Ans: SNRIs


Question: In addition to MDD SNRIs treat


Ans: Anxiety and neuropathic pain (peripheral neuropathy)


Question: Medication specific indications of duloxetine:


Ans: urinary incontinence and Fibromyalgia


Question: Medication specific indications of venlafaxine:


Ans: social anxiety, panic disorders, PTSD, OCD, postmenopausal hot flashes


Question: Six common side effects of SNRIs include:


Ans: Insomnia, nausea, sexual dysfunction, hypertension, sweating,
headaches


Question: Severe side effect of SNRIs in children/adolescents under age 25
years old: