NR 566 Midterm Questions With Complete Solutions
Extended spectrum
Piperacillin
• narrow-spectrum- penicillinase sensitive:
Streptococci, Neisseria, anaerobes
Narrow spectrum penicillin resistant
A. Aureus, Streptococci
Broad spectrum
Haemophililus influenza, E. Colin, proteus mirabilis,
enterococcu, neisseria gonorrhoea
Extended spectrum
Haemophilus influenza, E. Coli, proteus mirabilis, enterococci,
pseudomonas, enterobactor, klebsiella
Treatment of Acne Mild
Benzoyl peroxide (BP) or topical retinoid or combination
Treatment of Acne Moderate
Oral antibiotics Doxyсуcline Minocycline
Treatment of Acne Moderate
Comedolytics Retinoids Azelaic acid
Treatment of Acne Moderate
Combination • clindamycin/b enzoyl peroxide and tretinoin
,Treatment of Acne Severe
Oral antibiotic + Topical combination therapy Oral isotretinoin
Combination Doxycycline and topical retinoid
Treatment of Acne
Topical Drugs for Acne Oral Drugs for Acne Benzoyl peroxide
Isotretinoin Tretinoin Doxycycline
Isotretinoin (Accutane)
МОА • Derivative of Vitamin A Decreases • Sebum production
• Sebaceous gland size • Inflammation • Keratinization
Isotretinoin (Accutane)
Adverse Reactions - Avoid prolonged exposure to sunlight •
Decreased vision • Mood changes · Hepatitis • Significant
hyperlipidemia • Stop tetracycline
Isotretinoin (Accutane)
Monitoring • Lipids & LFTS every 2 weeks until stable • Birth
control measures • Vision & Hearing changes • Pain • Nausea
Alternations in mood
Isotretinoin (Accutane)
Black Box • Severe structural and cognitive defects in
developing fetus • Increased risk for spontaneous abortion
Isotretinoin (Accutane)
Contraindications • Women who may become pregnant • Those
not fully grown • History of • Diabetes • Hyperlipidemia •
Depression • Mental illness
, Isotretinoin (Accutane)
Baseline • CBC w/ Differential • Glucose Lipid panel • LFT •
Vision • Mental Health • Height if under 18
Cephalosporins
Instruct patients to report increase in stool frequency.
Tetracyclines
Advise patients to avoid prolonged exposure to sunlight
Macrolides
Patients should be instructed that GI disturbances can be
reduced by administering with meals.
Aminoglycosides
Patients must be instructed to report symptoms of ototoxicity.
Trimethoprim should be avoided in patients with which
deficiency?
Folate
Cephalosporins
Commonly used to treat bacterial infections, including otitis
media and gonococcal and pneumococcal infections.
Penicillins
Common drug used to treat bacterial infections.
Tetracyclines
Extended spectrum
Piperacillin
• narrow-spectrum- penicillinase sensitive:
Streptococci, Neisseria, anaerobes
Narrow spectrum penicillin resistant
A. Aureus, Streptococci
Broad spectrum
Haemophililus influenza, E. Colin, proteus mirabilis,
enterococcu, neisseria gonorrhoea
Extended spectrum
Haemophilus influenza, E. Coli, proteus mirabilis, enterococci,
pseudomonas, enterobactor, klebsiella
Treatment of Acne Mild
Benzoyl peroxide (BP) or topical retinoid or combination
Treatment of Acne Moderate
Oral antibiotics Doxyсуcline Minocycline
Treatment of Acne Moderate
Comedolytics Retinoids Azelaic acid
Treatment of Acne Moderate
Combination • clindamycin/b enzoyl peroxide and tretinoin
,Treatment of Acne Severe
Oral antibiotic + Topical combination therapy Oral isotretinoin
Combination Doxycycline and topical retinoid
Treatment of Acne
Topical Drugs for Acne Oral Drugs for Acne Benzoyl peroxide
Isotretinoin Tretinoin Doxycycline
Isotretinoin (Accutane)
МОА • Derivative of Vitamin A Decreases • Sebum production
• Sebaceous gland size • Inflammation • Keratinization
Isotretinoin (Accutane)
Adverse Reactions - Avoid prolonged exposure to sunlight •
Decreased vision • Mood changes · Hepatitis • Significant
hyperlipidemia • Stop tetracycline
Isotretinoin (Accutane)
Monitoring • Lipids & LFTS every 2 weeks until stable • Birth
control measures • Vision & Hearing changes • Pain • Nausea
Alternations in mood
Isotretinoin (Accutane)
Black Box • Severe structural and cognitive defects in
developing fetus • Increased risk for spontaneous abortion
Isotretinoin (Accutane)
Contraindications • Women who may become pregnant • Those
not fully grown • History of • Diabetes • Hyperlipidemia •
Depression • Mental illness
, Isotretinoin (Accutane)
Baseline • CBC w/ Differential • Glucose Lipid panel • LFT •
Vision • Mental Health • Height if under 18
Cephalosporins
Instruct patients to report increase in stool frequency.
Tetracyclines
Advise patients to avoid prolonged exposure to sunlight
Macrolides
Patients should be instructed that GI disturbances can be
reduced by administering with meals.
Aminoglycosides
Patients must be instructed to report symptoms of ototoxicity.
Trimethoprim should be avoided in patients with which
deficiency?
Folate
Cephalosporins
Commonly used to treat bacterial infections, including otitis
media and gonococcal and pneumococcal infections.
Penicillins
Common drug used to treat bacterial infections.
Tetracyclines
