Antipsychotics NURS 752 exam questions with \| \| \| \| \| \|
answers
Concept of 1st Gen binding thresholds - CORRECT ANSWERS
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✔✔The degree of D2 receptor binding in the mesolimbic system
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is close to 80% to have best effects for relieving psychosis.
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PROBLEM - 1st gen don't discriminate and block D2 receptors
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everywhere in the brain. When D2 increases over 80% in the
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dorsal striatum EPS effects occur and in the pituitary
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hyperprolactemia occur. \|
Three main features of neurolepsis include: - CORRECT
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ANSWERS ✔✔Psychomotor slowing, emotional quieting and
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affective indifference. \|
Positive symptoms include: - CORRECT ANSWERS ✔✔Delusions,
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Hallucinations and Thought Disorder. \| \| \|
Negative symptoms include: - CORRECT ANSWERS ✔✔•Loss or
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diminution of normal function \| \| \|
•Lack•Loss or diminution of normal function \| \| \| \| \|
•Lack of motivation
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•Poverty of speech \| \|
•Blunted affect \|
•Poor self-care
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•Social withdrawal of motivation
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, Overactivity or Underactivity of the mesocortical dopamine
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systemmediate the negative, cognitive, and affective symptoms \| \| \| \| \| \| \|
of schizophrenia? - CORRECT ANSWERS ✔✔Underactivity
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Cognitive symptoms include: - CORRECT ANSWERS
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✔✔•Disordered thinking \|
•Reduced ability to focus attention \| \| \| \|
•Prominent learning and memory difficulties \| \| \| \|
•Subtle changes may appear years before symptoms become
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florid
•Florid changes: Thinking and speech may be completely
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incomprehensible to others \| \|
Which drugs reverse effects of Parkinsonism? - CORRECT
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ANSWERS ✔✔•diphenhydramine, trihexyphenidyl, and
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benztropine.
What is the first drug approved for Tardive Dyskinesia? -
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CORRECT ANSWERS ✔✔Valbenazine (Ingrezza)
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symptoms of neuroleptic malignant syndrome - CORRECT
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ANSWERS ✔✔•Lead pipe" rigidity, sudden high fever, sweating,
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autonomic instability, dysrhythmias, fluctuations in blood
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pressure, altered level of consciousness, and seizures or coma
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may develop
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•Death can result from respiratory failure, cardiovascular
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collapse, dysrhythmias, and other causes
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answers
Concept of 1st Gen binding thresholds - CORRECT ANSWERS
\| \| \| \| \| \| \| \| \|
✔✔The degree of D2 receptor binding in the mesolimbic system
\| \| \| \| \| \| \| \| \| \|
is close to 80% to have best effects for relieving psychosis.
\| \| \| \| \| \| \| \| \| \| \|
PROBLEM - 1st gen don't discriminate and block D2 receptors
\| \| \| \| \| \| \| \| \| \|
everywhere in the brain. When D2 increases over 80% in the
\| \| \| \| \| \| \| \| \| \| \|
dorsal striatum EPS effects occur and in the pituitary
\| \| \| \| \| \| \| \| \|
hyperprolactemia occur. \|
Three main features of neurolepsis include: - CORRECT
\| \| \| \| \| \| \| \|
ANSWERS ✔✔Psychomotor slowing, emotional quieting and
\| \| \| \| \| \|
affective indifference. \|
Positive symptoms include: - CORRECT ANSWERS ✔✔Delusions,
\| \| \| \| \| \| \|
Hallucinations and Thought Disorder. \| \| \|
Negative symptoms include: - CORRECT ANSWERS ✔✔•Loss or
\| \| \| \| \| \| \| \|
diminution of normal function \| \| \|
•Lack•Loss or diminution of normal function \| \| \| \| \|
•Lack of motivation
\| \|
•Poverty of speech \| \|
•Blunted affect \|
•Poor self-care
\|
•Social withdrawal of motivation
\| \| \|
, Overactivity or Underactivity of the mesocortical dopamine
\| \| \| \| \| \| \|
systemmediate the negative, cognitive, and affective symptoms \| \| \| \| \| \| \|
of schizophrenia? - CORRECT ANSWERS ✔✔Underactivity
\| \| \| \| \|
Cognitive symptoms include: - CORRECT ANSWERS
\| \| \| \| \| \|
✔✔•Disordered thinking \|
•Reduced ability to focus attention \| \| \| \|
•Prominent learning and memory difficulties \| \| \| \|
•Subtle changes may appear years before symptoms become
\| \| \| \| \| \| \| \|
florid
•Florid changes: Thinking and speech may be completely
\| \| \| \| \| \| \| \|
incomprehensible to others \| \|
Which drugs reverse effects of Parkinsonism? - CORRECT
\| \| \| \| \| \| \| \|
ANSWERS ✔✔•diphenhydramine, trihexyphenidyl, and
\| \| \| \|
benztropine.
What is the first drug approved for Tardive Dyskinesia? -
\| \| \| \| \| \| \| \| \| \|
CORRECT ANSWERS ✔✔Valbenazine (Ingrezza)
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symptoms of neuroleptic malignant syndrome - CORRECT
\| \| \| \| \| \| \|
ANSWERS ✔✔•Lead pipe" rigidity, sudden high fever, sweating,
\| \| \| \| \| \| \| \|
autonomic instability, dysrhythmias, fluctuations in blood
\| \| \| \| \| \|
pressure, altered level of consciousness, and seizures or coma
\| \| \| \| \| \| \| \| \|
may develop
\|
•Death can result from respiratory failure, cardiovascular
\| \| \| \| \| \| \|
collapse, dysrhythmias, and other causes
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